Publications by authors named "Lena Backlund"

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Pathway-Specific Polygenic Scores for Predicting Clinical Lithium Treatment Response in Patients With Bipolar Disorder.
Nigussie T Sharew, Scott R Clark, Sergi Papiol, Urs Heilbronner, Franziska Degenhardt, Lena Backlund

Biol Psychiatry Glob Open Sci· September 2025

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Immune, Developmental, and Synaptic Pathways Define Bipolar Disorder Clinical Heterogeneity.
Tracey van der Veen, Markos Tesfaye, Jessica Mei Kay Yang, Toni Boltz, Friederike S David, Lena Backlund

medRxiv· June 2025

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On-chip colorimetric assay for determining serum lithium concentration from whole blood.
Carl Olsson, Janosch Hauser, Federico Ribet, Fredrik Wikström, André Görgens, Lena Backlund

Lab Chip· April 2025

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Genomics yields biological and phenotypic insights into bipolar disorder.
Kevin S O'Connell, Maria Koromina, Tracey van der Veen, Toni Boltz, Friederike S David, Lena Backlund

Nature· March 2025

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Pathway-Specific Polygenic Scores for Lithium Response for Predicting Clinical Lithium Treatment Response in Patients with Bipolar Disorder.
Nigussie T Sharew, Scott R Clark, Sergi Papiol, Urs Heilbronner, Franziska Degenhardt, Lena Backlund

medRxiv· March 2025

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Lithium response in bipolar disorder is associated with focal adhesion and PI3K-Akt networks: a multi-omics replication study.
Anna H Ou, Sara B Rosenthal, Mazda Adli, Kazufumi Akiyama, Nirmala Akula, Lena Backlund

Transl Psychiatry· February 2024

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Association of polygenic score and the involvement of cholinergic and glutamatergic pathways with lithium treatment response in patients with bipolar disorder.
Azmeraw T Amare, Anbupalam Thalamuthu, Klaus Oliver Schubert, Janice M Fullerton, Muktar Ahmed, Lena Backlund

Mol Psychiatry· December 2023

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Lithium Response in Bipolar Disorder is Associated with Focal Adhesion and PI3K-Akt Networks: A Multi-omics Replication Study.
John Kelsoe, Anna Ou, Sara Rosenthal, Mazda Adli, Kazufumi Akiyama, Lena Backlund

Res Sq· October 2023

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Lithium and risk of cardiovascular disease, dementia and venous thromboembolism.
Katja Ponzer, Vincent Millischer, Martin Schalling, Mika Gissler, Catharina Lavebratt, Lena Backlund

Bipolar Disord· August 2023

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Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder.
Marisol Herrera-Rivero, Karina Gutiérrez-Fragoso, Anbupalam Thalamuthu, Azmeraw T Amare, Mazda Adli, Lena Backlund

Res Sq· June 2023

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Prevalence and characteristics of unipolar mania in a low-income country setting: population-based data from the Butajira cohort, rural Ethiopia.
Fredrik Wikström, Hugo Zeberg, Rosie Mayston, Lena Backlund, Abebaw Fekadu

Soc Psychiatry Psychiatr Epidemiol· April 2023

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Determination of lithium concentration in capillary blood using volumetric dried blood spots.
Fredrik Wikström, Carl Olsson, Bonita Palm, Niclas Roxhed, Lena Backlund

J Pharm Biomed Anal· April 2023

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Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder.
Azmeraw Amare, Anbupalam Thalamuthu, Klaus Oliver Schubert, Janice Fullerton, Muktar Ahmed, Lena Backlund

Res Sq· February 2023

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Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach - CORRIGENDUM.
Micah Cearns, Azmeraw T Amare, Klaus Oliver Schubert, Anbupalam Thalamuthu, Joseph Frank, Lena Backlund

Br J Psychiatry· August 2022

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Correction: Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.
Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T Amare, Joseph Frank, Fabian Streit, Lena Backlund

Transl Psychiatry· July 2022

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Using polygenic scores and clinical data for bipolar disorder patient stratification and lithium response prediction: machine learning approach.
Micah Cearns, Azmeraw T Amare, Klaus Oliver Schubert, Anbupalam Thalamuthu, Joseph Frank, Lena Backlund

Br J Psychiatry· April 2022

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Association of Attention-Deficit/Hyperactivity Disorder and Depression Polygenic Scores with Lithium Response: A Consortium for Lithium Genetics Study.
Brandon J Coombes, Vincent Millischer, Anthony Batzler, Beth Larrabee, Liping Hou, Lena Backlund

Complex Psychiatry· December 2021

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Combining schizophrenia and depression polygenic risk scores improves the genetic prediction of lithium response in bipolar disorder patients.
Klaus Oliver Schubert, Anbupalam Thalamuthu, Azmeraw T Amare, Joseph Frank, Fabian Streit, Lena Backlund

Transl Psychiatry· November 2021

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HLA-DRB1 and HLA-DQB1 genetic diversity modulates response to lithium in bipolar affective disorders.
Sigrid Le Clerc, Laura Lombardi, Bernhard T Baune, Azmeraw T Amare, Klaus Oliver Schubert, Lena Backlund

Sci Rep· September 2021

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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
Niamh Mullins, Andreas J Forstner, Kevin S O'Connell, Brandon Coombes, Jonathan R I Coleman, Lena Backlund

Nat Genet· June 2021

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Prediction of lithium response using genomic data.
William Stone, Abraham Nunes, Kazufumi Akiyama, Nirmala Akula, Raffaella Ardau, Lena Backlund

Sci Rep· January 2021

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