Publications by authors named "Leonard C Edelstein"

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Human and mouse PAR4 are functionally distinct receptors: Studies in novel humanized mice.
Stephanie A Renna, James V Michael, Xianguo Kong, Lin Ma, Peisong Ma, Leonard C Edelstein

J Thromb Haemost· May 2022

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PCTP contributes to human platelet activation by enhancing dense granule secretion.
Shaji Abraham, Lin Ma, Xianguo Kong, Shayan Askari, Leonard C Edelstein

Thromb Res· June 2021

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miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin.
Seema Bhatlekar, Bhanu K Manne, Indranil Basak, Leonard C Edelstein, Emilia Tugolukova

Blood· October 2020

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Bayesian modelling of high-throughput sequencing assays with malacoda.
Andrew R Ghazi, Xianguo Kong, Ed S Chen, Leonard C Edelstein, Chad A Shaw

PLoS Comput Biol· July 2020

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Anti-apoptotic increases megakaryocyte proplatelet formation in cultures of human cord blood.
Seema Bhatlekar, Indranil Basak, Leonard C Edelstein, Robert A Campbell, Cory R Lindsey

Haematologica· October 2019

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Horizontal RNA transfer goes deep: platelet consumption and microRNA utilization by vascular smooth muscle cells.
Lawrence E Goldfinger, Leonard C Edelstein

J Thromb Haemost· July 2019

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Functionalization of CD36 cardiovascular disease and expression associated variants by interdisciplinary high throughput analysis.
Namrata Madan, Andrew R Ghazi, Xianguo Kong, Edward S Chen, Chad A Shaw, Leonard C Edelstein

PLoS Genet· July 2019

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Identification of the Regulatory Elements and Target Genes of Megakaryopoietic Transcription Factor MEF2C.
Xianguo Kong, Lin Ma, Edward Chen, Chad A Shaw, Leonard C Edelstein

Thromb Haemost· May 2019

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miR-15a-5p regulates expression of multiple proteins in the megakaryocyte GPVI signaling pathway.
Indranil Basak, Seema Bhatlekar, Bhanu K Manne, Micelle Stoller, Sarah Hugo, Leonard C Edelstein

J Thromb Haemost· March 2019

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Effects of genetic variation in protease activated receptor 4 after an acute coronary syndrome: Analysis from the TRACER trial.
Pierluigi Tricoci, Megan Neely, Michael J Whitley, Leonard C Edelstein, Lukas M Simon

Blood Cells Mol Dis· September 2018

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Design tools for MPRA experiments.
Andrew R Ghazi, Edward S Chen, David M Henke, Namrata Madan, Leonard C Edelstein

Bioinformatics· August 2018

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Genetic Variant in Human PAR (Protease-Activated Receptor) 4 Enhances Thrombus Formation Resulting in Resistance to Antiplatelet Therapeutics.
Benjamin E Tourdot, Hannah Stoveken, Derek Trumbo, Jennifer Yeung, Yogendra Kanthi, Leonard C Edelstein

Arterioscler Thromb Vasc Biol· July 2018

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Platelet microparticles infiltrating solid tumors transfer miRNAs that suppress tumor growth.
James V Michael, Jeremy G T Wurtzel, Guang Fen Mao, A Koneti Rao, Mikhail A Kolpakov, Leonard C Edelstein

Blood· August 2017

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The role of platelet microvesicles in intercellular communication.
Leonard C Edelstein

Platelets· May 2017

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Identification of a functional genetic variant driving racially dimorphic platelet gene expression of the thrombin receptor regulator, PCTP.
Xianguo Kong, Lukas M Simon, Michael Holinstat, Chad A Shaw, Paul F Bray, Leonard C Edelstein

Thromb Haemost· May 2017

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TULA-2 (T-Cell Ubiquitin Ligand-2) Inhibits the Platelet Fc Receptor for IgG IIA (FcγRIIA) Signaling Pathway and Heparin-Induced Thrombocytopenia in Mice.
Yuhang Zhou, Shaji Abraham, Stephanie Renna, Leonard C Edelstein, Carol A Dangelmaier

Arterioscler Thromb Vasc Biol· December 2016

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Integrative Multi-omic Analysis of Human Platelet eQTLs Reveals Alternative Start Site in Mitofusin 2.
Lukas M Simon, Edward S Chen, Leonard C Edelstein, Xianguo Kong, Seema Bhatlekar

Am J Hum Genet· May 2016

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MicroRNAs in Platelet Physiology and Function.
Cory R Lindsay, Leonard C Edelstein

Semin Thromb Hemost· April 2016

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Anti-miR-148a regulates platelet FcγRIIA signaling and decreases thrombosis in vivo in mice.
Yuhang Zhou, Shaji Abraham, Pierrette Andre, Leonard C Edelstein, Chad A Shaw

Blood· December 2015

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MicroRNA expression differences in human hematopoietic cell lineages enable regulated transgene expression.
Raul Teruel-Montoya, Xianguo Kong, Shaji Abraham, Lin Ma, Satya P Kunapuli, Leonard C Edelstein

PLoS One· March 2015

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Mechanism of race-dependent platelet activation through the protease-activated receptor-4 and Gq signaling axis.
Benjamin E Tourdot, Stanley Conaway, Katrin Niisuke, Leonard C Edelstein, Paul F Bray

Arterioscler Thromb Vasc Biol· December 2014

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Common variants in the human platelet PAR4 thrombin receptor alter platelet function and differ by race.
Leonard C Edelstein, Lukas M Simon, Cory R Lindsay, Xianguo Kong, Raúl Teruel-Montoya

Blood· November 2014

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Human platelet microRNA-mRNA networks associated with age and gender revealed by integrated plateletomics.
Lukas M Simon, Leonard C Edelstein, Srikanth Nagalla, Angela B Woodley, Edward S Chen

Blood· April 2014

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Racial differences in human platelet PAR4 reactivity reflect expression of PCTP and miR-376c.
Leonard C Edelstein, Lukas M Simon, Raúl Teruel Montoya, Michael Holinstat, Edward S Chen

Nat Med· December 2013

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The complex transcriptional landscape of the anucleate human platelet.
Paul F Bray, Steven E McKenzie, Leonard C Edelstein, Srikanth Nagalla, Kathleen Delgrosso

BMC Genomics· January 2013

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