Publications by authors named "Leopold Flohe"

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50 Years of Organoselenium Chemistry, Biochemistry and Reactivity: Mechanistic Understanding, Successful and Controversial Stories.
Andrea Madabeni, Marco Bortoli, Pablo A Nogara, Giovanni Ribaudo, Marco Dalla Tiezza

Chemistry· December 2024

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The glutathione peroxidase family: Discoveries and mechanism.
Leopold Flohé, Stefano Toppo, Laura Orian

Free Radic Biol Med· July 2022

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Fifty years of selenoenzyme research: Discoveries, state-of-the-art and future directions.
Leopold Flohé, Matilde Maiorino, Fulvio Ursini

Free Radic Biol Med· April 2022

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Selenium-Catalyzed Reduction of Hydroperoxides in Chemistry and Biology.
Laura Orian, Leopold Flohé

Antioxidants (Basel)· September 2021

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Proton Transfer and S 2 Reactions as Steps of Fast Selenol and Thiol Oxidation in Proteins: A Model Molecular Study Based on GPx.
Marco Dalla Tiezza, F Matthias Bickelhaupt, Leopold Flohé, Laura Orian

Chempluschem· April 2021

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Proton Transfer and S 2 Reactions as Steps of Fast Selenol and Thiol Oxidation in Proteins: A Model Molecular Study Based on GPx.
Marco Dalla Tiezza, F Matthias Bickelhaupt, Leopold Flohé, Laura Orian

Chempluschem· April 2021

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Looking Back at the Early Stages of Redox Biology.
Leopold Flohé

Antioxidants (Basel)· December 2020

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Regulatory Phenomena in the Glutathione Peroxidase Superfamily.
Regina Brigelius-Flohé, Leopold Flohé

Antioxid Redox Signal· September 2020

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Selenium and redox signaling.
Regina Brigelius-Flohé, Leopold Flohé

Arch Biochem Biophys· March 2017

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Selenoprotein Gene Nomenclature.
Vadim N Gladyshev, Elias S Arnér, Marla J Berry, Regina Brigelius-Flohé, Elspeth A Bruford

J Biol Chem· November 2016

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Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids.
Diego Benítez, Andrea Medeiros, Lucía Fiestas, Esteban A Panozzo-Zenere, Franziska Maiwald

PLoS Negl Trop Dis· April 2016

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Helmut Sies and the compartmentation of hydroperoxide metabolism.
Leopold Flohé

Arch Biochem Biophys· April 2016

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Selenocysteine oxidation in glutathione peroxidase catalysis: an MS-supported quantum mechanics study.
Laura Orian, Pierluigi Mauri, Antonella Roveri, Stefano Toppo, Louise Benazzi

Free Radic Biol Med· October 2015

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Genetic and chemical analyses reveal that trypanothione synthetase but not glutathionylspermidine synthetase is essential for Leishmania infantum.
André F Sousa, Ana G Gomes-Alves, Diego Benítez, Marcelo A Comini, Leopold Flohé

Free Radic Biol Med· August 2014

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Redox regulation by glutathione needs enzymes.
Carsten Berndt, Christopher H Lillig, Leopold Flohé

Front Pharmacol· August 2014

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Molecular dynamics reveal binding mode of glutathionylspermidine by trypanothione synthetase.
Oliver Koch, Daniel Cappel, Monika Nocker, Timo Jäger, Leopold Flohé

PLoS One· September 2013

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Identification of M. tuberculosis thioredoxin reductase inhibitors based on high-throughput docking using constraints.
Oliver Koch, Timo Jäger, Kristin Heller, Purushothama Chary Khandavalli, Jette Pretzel

J Med Chem· June 2013

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The fairytale of the GSSG/GSH redox potential.
Leopold Flohé

Biochim Biophys Acta· May 2013

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The trypanothione system and its implications in the therapy of trypanosomatid diseases.
Leopold Flohé

Int J Med Microbiol· October 2012

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The trypanothione system and the opportunities it offers to create drugs for the neglected kinetoplast diseases.
Leopold Flohé

Biotechnol Adv· July 2012

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Basic principles and emerging concepts in the redox control of transcription factors.
Regina Brigelius-Flohé, Leopold Flohé

Antioxid Redox Signal· October 2011

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A fast virtual screening approach to identify structurally diverse inhibitors of trypanothione reductase.
Giorgio Maccari, Timo Jaeger, Francesca Moraca, Mariangela Biava, Leopold Flohé

Bioorg Med Chem Lett· September 2011

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A comparison of thiol peroxidase mechanisms.
Leopold Flohé, Stefano Toppo, Giorgio Cozza, Fulvio Ursini

Antioxid Redox Signal· August 2011

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