Publications by authors named "Lesley A Pearce"

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CUB Domain-Containing Protein 1 (CDCP1) is a rational target for the development of imaging tracers and antibody-drug conjugates for cancer detection and therapy.
Tashbib Khan, Nicholas J Lyons, Madeline Gough, Kayden K X Kwah, Tahleesa J Cuda, Lesley A Pearce

Theranostics· October 2022

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Preclinical Evaluation of a Fluorescent Probe Targeting Receptor CDCP1 for Identification of Ovarian Cancer.
Yaowu He, Tashbib Khan, Thomas Kryza, Martina L Jones, Justin B Goh, Lesley A Pearce

Mol Pharm· September 2021

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Enzyme mediated incorporation of zirconium-89 or copper-64 into a fragment antibody for same day imaging of epidermal growth factor receptor.
Stacey E Rudd, Jessica K Van Zuylekom, Anna Raicevic, Lesley A Pearce, Carleen Cullinane

Chem Sci· July 2021

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Dual Site-Specific Labeling of an Antibody Fragment through Sortase A and π-Clamp Conjugation.
Michael D Lee, Wing Yin Tong, Thomas Nebl, Lesley A Pearce, Tam M Pham

Bioconjug Chem· October 2019

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CD52 glycan binds the proinflammatory B box of HMGB1 to engage the Siglec-10 receptor and suppress human T cell function.
Esther Bandala-Sanchez, Naiara G Bediaga, Ethan D Goddard-Borger, Katrina Ngui, Gaetano Naselli, Lesley A Pearce

Proc Natl Acad Sci U S A· July 2018

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Structural characterization by transmission electron microscopy and immunoreactivity of recombinant Hendra virus nucleocapsid protein expressed and purified from Escherichia coli.
Lesley A Pearce, Meng Yu, Lynne J Waddington, Jennifer A Barr, Judith A Scoble

Protein Expr Purif· December 2015

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Structural studies of the tethered N-terminus of the Alzheimer's disease amyloid-β peptide.
Rebecca M Nisbet, Stewart D Nuttall, Remy Robert, Joanne M Caine, Olan Dolezal, Lesley A Pearce

Proteins· October 2013

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Biochemical characterization of individual human glycosylated pro-insulin-like growth factor (IGF)-II and big-IGF-II isoforms associated with cancer.
Sameer A Greenall, John D Bentley, Lesley A Pearce, Judith A Scoble, Lindsay G Sparrow

J Biol Chem· January 2013

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Engineering of an anti-epidermal growth factor receptor antibody to single chain format and labeling by Sortase A-mediated protein ligation.
Mariusz P Madej, Gregory Coia, Charlotte C Williams, Joanne M Caine, Lesley A Pearce

Biotechnol Bioeng· June 2012

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Germline humanization of a murine Abeta antibody and crystal structure of the humanized recombinant Fab fragment.
Remy Robert, Victor A Streltsov, Janet Newman, Lesley A Pearce, Kim L Wark

Protein Sci· February 2010

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Kinetic screening of antibody-Im7 conjugates by capture on a colicin E7 DNase domain using optical biosensors.
Ralf J Hosse, Leigh Tay, Meghan K Hattarki, Luisa Pontes-Braz, Lesley A Pearce

Anal Biochem· February 2009

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