Publications by authors named "Leslie Elsner"

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Sensitivity of Pancreatic Cancer Cell Lines to Clinically Approved FAK Inhibitors: Enhanced Cytotoxicity Through Combination with Oncolytic Coxsackievirus B3.
Anja Geisler, Babette Dieringer, Leslie Elsner, Maxim Girod, Sophie Van Linthout

Int J Mol Sci· July 2025

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Optimized Directed Virus Evolution to Accelerate the Generation of Oncolytic Coxsackievirus B3 Adapted to Resistant Colorectal Cancer Cells.
Leslie Elsner, Babette Dieringer, Anja Geisler, Maxim Girod, Sophie Van Linthout

Viruses· December 2024

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Oncolytic Coxsackievirus B3 Strain PD-H Is Effective Against a Broad Spectrum of Pancreatic Cancer Cell Lines and Induces a Growth Delay in Pancreatic KPC Cell Tumors In Vivo.
Anja Geisler, Babette Dieringer, Leslie Elsner, Robert Klopfleisch, Jens Kurreck

Int J Mol Sci· October 2024

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Combination of FOLFOXIRI Drugs with Oncolytic Coxsackie B3 Virus PD-H Synergistically Induces Oncolysis in the Refractory Colorectal Cancer Cell Line Colo320.
Maxim Girod, Anja Geisler, Luisa Hinze, Leslie Elsner, Babette Dieringer

Int J Mol Sci· May 2024

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Fast Track Adaptation of Oncolytic Coxsackie B3 Virus to Resistant Colorectal Cancer Cells - a Method to Personalize Virotherapy.
Leslie Elsner, Lisanne Heimann, Anja Geisler, Babette Dieringer, Klaus-Peter Knoch

Biol Proced Online· April 2024

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Lipid nanoparticle-encapsulated, chemically modified anti-adenoviral siRNAs inhibit hepatic adenovirus infection in immunosuppressed Syrian hamsters.
Anja Geisler, Babette Dieringer, Leslie Elsner, Karin Klingel, Robert Klopfleisch

Mol Ther Nucleic Acids· June 2023

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Generation of a microRNA-Regulated Oncolytic Coxsackievirus B3.
Babette Dieringer, Leslie Elsner, Ahmet Hazini, Jens Kurreck, Henry Fechner

Methods Mol Biol· June 2022

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Cr-release to monitor NK cell cytotoxicity.
Leslie Elsner, Ralf Dressel

Methods Enzymol· January 2021

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CD8-T Cells With Specificity for a Model Antigen in Cardiomyocytes Can Become Activated After Transverse Aortic Constriction but Do Not Accelerate Progression to Heart Failure.
Carina Gröschel, André Sasse, Sebastian Monecke, Charlotte Röhrborn, Leslie Elsner

Front Immunol· October 2019

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T helper cells with specificity for an antigen in cardiomyocytes promote pressure overload-induced progression from hypertrophy to heart failure.
Carina Gröschel, André Sasse, Charlotte Röhrborn, Sebastian Monecke, Michael Didié, Leslie Elsner

Sci Rep· November 2017

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Immunological Properties of Murine Parthenogenetic Stem Cells and Their Differentiation Products.
Hannah Johannsen, Vijayakumar Muppala, Carina Gröschel, Sebastian Monecke, Leslie Elsner

Front Immunol· August 2017

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Efficient Killing of Murine Pluripotent Stem Cells by Natural Killer (NK) Cells Requires Activation by Cytokines and Partly Depends on the Activating NK Receptor NKG2D.
Carina Gröschel, Daniela Hübscher, Jessica Nolte, Sebastian Monecke, André Sasse, Leslie Elsner

Front Immunol· July 2017

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The Tumorigenicity of Multipotent Adult Germline Stem Cells Transplanted into the Heart Is Affected by Natural Killer Cells and by Cyclosporine A Independent of Its Immunosuppressive Effects.
Daniela Hübscher, Diana Kaiser, Leslie Elsner, Sebastian Monecke, Ralf Dressel

Front Immunol· February 2017

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Human Induced Pluripotent Stem Cells Are Targets for Allogeneic and Autologous Natural Killer (NK) Cells and Killing Is Partly Mediated by the Activating NK Receptor DNAM-1.
Vanessa Kruse, Carina Hamann, Sebastian Monecke, Lukas Cyganek, Leslie Elsner

PLoS One· April 2016

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The MICA-129Met/Val dimorphism affects plasma membrane expression and shedding of the NKG2D ligand MICA.
Antje Isernhagen, Daniela Schilling, Sebastian Monecke, Pranali Shah, Leslie Elsner

Immunogenetics· February 2016

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The MICA-129 dimorphism affects NKG2D signaling and outcome of hematopoietic stem cell transplantation.
Antje Isernhagen, Dörthe Malzahn, Elena Viktorova, Leslie Elsner, Sebastian Monecke

EMBO Mol Med· November 2015

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Pluripotent stem cells are highly susceptible targets for syngeneic, allogeneic, and xenogeneic natural killer cells.
Ralf Dressel, Jessica Nolte, Leslie Elsner, Peter Novota, Kaomei Guan

FASEB J· July 2010

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The exocytosis of lytic granules is impaired in Vti1b- or Vamp8-deficient CTL leading to a reduced cytotoxic activity following antigen-specific activation.
Ralf Dressel, Leslie Elsner, Peter Novota, Namita Kanwar, Gabriele Fischer von Mollard

J Immunol· July 2010

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The endogenous danger signals HSP70 and MICA cooperate in the activation of cytotoxic effector functions of NK cells.
Leslie Elsner, Perris F Flügge, Jingky Lozano, Vijayakumar Muppala, Britta Eiz-Vesper

J Cell Mol Med· April 2010

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Multipotent adult germ-line stem cells, like other pluripotent stem cells, can be killed by cytotoxic T lymphocytes despite low expression of major histocompatibility complex class I molecules.
Ralf Dressel, Kaomei Guan, Jessica Nolte, Leslie Elsner, Sebastian Monecke

Biol Direct· August 2009

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The tumorigenicity of mouse embryonic stem cells and in vitro differentiated neuronal cells is controlled by the recipients' immune response.
Ralf Dressel, Jan Schindehütte, Tanja Kuhlmann, Leslie Elsner, Peter Novota

PLoS One· July 2008

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The heat shock protein HSP70 promotes mouse NK cell activity against tumors that express inducible NKG2D ligands.
Leslie Elsner, Vijayakumar Muppala, Mathias Gehrmann, Jingky Lozano, Dörthe Malzahn

J Immunol· October 2007

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