Publications by authors named "Leslie Obert"

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Pharmaceutical Practice Considerations Regarding Adoption of the Race-Free Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) 2021 Equations.
Ruth Tarzi, Jennifer McKenzie, Michel Reid, Sophia Goodison, James Oyee, Leslie A Obert

Am J Kidney Dis· December 2025

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Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses .
Rocio Montes de Oca, Alireza S Alavi, Nick Vitali, Sabyasachi Bhattacharya, Christina Blackwell, Leslie Obert

Mol Cancer Ther· October 2021

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A Review of Specific Biomarkers of Chronic Renal Injury and Their Potential Application in Nonclinical Safety Assessment Studies.
Leslie A Obert, Susan A Elmore, Daniela Ennulat, Kendall S Frazier

Toxicol Pathol· July 2021

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Congenital Unilateral Renal Aplasia in a Cynomolgus Monkey () With Investigation Into Potential Pathogenesis.
Leslie A Obert, Andrew Suttie, Mohamoud Abdi, Tracy Gales, David Dwyer, Nicola Robertson

Toxicol Pathol· August 2020

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Expression of Hematopoietic Stem and Endothelial Cell Markers in Canine Hemangiosarcoma.
Satoko Kakiuchi-Kiyota, Leslie A Obert, Danielle M Crowell, Shuhua Xia, Marc D Roy

Toxicol Pathol· April 2020

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Author Correction: Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer.
Guoyun Zhu, Davide Foletti, Xiaohui Liu, Sheng Ding, Jody Melton Witt, Leslie Obert

Sci Rep· November 2019

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Intrarenal Renin-Angiotensin System Involvement in the Pathogenesis of Chronic Progressive Nephropathy-Bridging the Informational Gap Between Disciplines.
Leslie A Obert, Kendall S Frazier

Toxicol Pathol· October 2019

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Targeting CLDN18.2 by CD3 Bispecific and ADC Modalities for the Treatments of Gastric and Pancreatic Cancer.
Guoyun Zhu, Davide Foletti, Xiaohui Liu, Sheng Ding, Jody Melton Witt, Leslie Obert

Sci Rep· June 2019

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Kidney Pathology and Investigative Nephrotoxicology Strategies Across Species.
Kendall S Frazier, Anne M Ryan, Richard A Peterson, Leslie A Obert

Semin Nephrol· March 2019

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Drug-induced Glomerulonephritis: The Spectre of Biotherapeutic and Antisense Oligonucleotide Immune Activation in the Kidney.
Kendall S Frazier, Leslie A Obert

Toxicol Pathol· December 2018

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From the Cover: Fenretinide, Troglitazone, and Elmiron Add to Weight of Evidence Support for Hemangiosarcoma Mode-of-Action From Studies in Mice.
Jon C Cook, Leslie A Obert, Petra Koza-Taylor, Timothy M Coskran, Alan C Opsahl

Toxicol Sci· January 2018

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Induction of endogenous retroelements as a potential mechanism for mouse-specific drug-induced carcinogenicity.
Timothy M Coskran, Zhijie Jiang, James E Klaunig, Dixie L Mager, Leslie Obert, Andrew Robertson

PLoS One· September 2017

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Liver Microvascular Injury and Thrombocytopenia of Antibody-Calicheamicin Conjugates in Cynomolgus Monkeys-Mechanism and Monitoring.
Magali Guffroy, Hadi Falahatpisheh, Kathleen Biddle, John Kreeger, Leslie Obert

Clin Cancer Res· April 2017

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Hemodynamic correlates of drug-induced vascular injury in the rat using high-frequency ultrasound imaging.
Terri A Swanson, Teri Conte, Ben Deeley, Susan Portugal, John M Kreeger, Leslie A Obert

Toxicol Pathol· June 2014

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Pregabalin induces hepatic hypoxia and increases endothelial cell proliferation in mice, a process inhibited by dietary vitamin E supplementation.
Kay A Criswell, Jon C Cook, Dennis Morse, Michael Lawton, Christopher Somps, Leslie Obert

Toxicol Sci· July 2012

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Increased serum enzyme levels associated with kupffer cell reduction with no signs of hepatic or skeletal muscle injury.
Zaher A Radi, Petra H Koza-Taylor, Rosonald R Bell, Leslie A Obert, Herbert A Runnels

Am J Pathol· July 2011

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Effects of the histamine H1 antagonist chlorcyclizine on rat fetal palate development.
Brian P Enright, Yi-Zhong Gu, Ronald D Snyder, Ravi R Dugyala, Leslie A Obert, Robert W Veneziale

Birth Defects Res B Dev Reprod Toxicol· December 2010

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Towards consensus practices to qualify safety biomarkers for use in early drug development.
Frank D Sistare, Frank Dieterle, Sean Troth, Daniel J Holder, David Gerhold, Leslie Ann Obert

Nat Biotechnol· May 2010

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Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium.
Frank Dieterle, Frank Sistare, Federico Goodsaid, Marisa Papaluca, Josef S Ozer, Leslie Obert

Nat Biotechnol· May 2010

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The role of hypoxia in 2-butoxyethanol-induced hemangiosarcoma.
Daphna Laifenfeld, Annalyn Gilchrist, David Drubin, Milena Jorge, Sean F Eddy, Leslie A Obert

Toxicol Sci· January 2010

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Targeted disruption of murine organic anion-transporting polypeptide 1b2 (Oatp1b2/Slco1b2) significantly alters disposition of prototypical drug substrates pravastatin and rifampin.
Hani Zaher, Henriette E Meyer zu Schwabedissen, Rommel G Tirona, Melissa L Cox, Leslie A Obert

Mol Pharmacol· August 2008

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Expression of Ki-67 in the uterus during various stages of the estrous cycle in rats.
Rosemary A Marusak, Zaher A Radi, Leslie Obert

Exp Toxicol Pathol· November 2007

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An immunohistochemical approach to differentiate hepatic lipidosis from hepatic phospholipidosis in rats.
Leslie A Obert, Gregg P Sobocinski, Walter F Bobrowski, Alan L Metz, Mark D Rolsma, Robert W Dunstan

Toxicol Pathol· August 2007

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A practical method to determine the amount of tissue to analyze using laser scanning cytometry.
John A Wijsman, Leslie A Obert, Jerome Paulissen, Rosario Garrido, Katherine A Toy, Robert W Dunstan

Cytometry A· July 2007

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Detection of cytokine protein expression in mouse lung homogenates using suspension bead array.
Eric McDuffie, Leslie Obert, Jonathan Chupka, Robert Sigler

J Inflamm (Lond)· November 2006

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