Publications by authors named "Lester Manly"

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Electron Capture Dissociation for Discovery Top-Down Proteomics of Peptides and Small Proteins on Chromatographic Time Scales.
Lester S Manly, Anne M Roberts, Joseph S Beckman, Blaine R Roberts

J Am Soc Mass Spectrom· October 2025

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PET Quantification in Healthy Humans of Cyclooxygenase-2, a Potential Biomarker of Neuroinflammation.
Xuefeng Yan, Martin Noergaard, Cheryl L Morse, Jeih-San Liow, Jinsoo Hong, Lester S Manly

J Nucl Med· March 2025

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In vivo evaluation of a novel F-labeled PET radioligand for translocator protein 18 kDa (TSPO) in monkey brain.
Xuefeng Yan, Fabrice G Siméon, Jeih-San Liow, Cheryl L Morse, Jose A Montero Santamaria, Lester S Manly

Eur J Nucl Med Mol Imaging· August 2023

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Candidate 3-benzazepine-1-ol type GluN2B receptor radioligands (C-NR2B-Me enantiomers) have high binding in cerebellum but not to σ1 receptors.
Lisheng Cai, Jeih-San Liow, Cheryl L Morse, Sanjay Telu, Riley Davies, Lester S Manly

EJNMMI Res· April 2023

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Whole-Body PET Imaging in Humans Shows That C-PS13 Is Selective for Cyclooxygenase-1 and Can Measure the In Vivo Potency of Nonsteroidal Antiinflammatory Drugs.
Min-Jeong Kim, Fernanda Juarez Anaya, Lester S Manly, Jae-Hoon Lee, Jinsoo Hong

J Nucl Med· January 2023

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Cyclooxygenases as Potential PET Imaging Biomarkers to Explore Neuroinflammation in Dementia.
Bruny V Kenou, Lester S Manly, Sara B Rubovits, Somachukwu A Umeozulu, Maia G Van Buskirk

J Nucl Med· June 2022

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Synthesis and Screening in Mice of Fluorine-Containing PET Radioligands for TSPO: Discovery of a Promising F-Labeled Ligand.
Fabrice G Siméon, Jae-Hoon Lee, Cheryl L Morse, Ian Stukes, Sami S Zoghbi, Lester S Manly

J Med Chem· November 2021

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[C]deschloroclozapine is an improved PET radioligand for quantifying a human muscarinic DREADD expressed in monkey brain.
Xuefeng Yan, Sanjay Telu, Rachel M Dick, Jeih-San Liow, Paolo Zanotti-Fregonara, Lester S Manly

J Cereb Blood Flow Metab· October 2021

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Synthesis of [F]PS13 and Evaluation as a PET Radioligand for Cyclooxygenase-1 in Monkey.
Carlotta Taddei, Cheryl L Morse, Min-Jeong Kim, Jeih-San Liow, Jose Montero Santamaria, Lester S Manly

ACS Chem Neurosci· February 2021

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Discovery, Radiolabeling, and Evaluation of Subtype-Selective Inhibitors for Positron Emission Tomography Imaging of Brain Phosphodiesterase-4D.
Yuichi Wakabayashi, Sanjay Telu, Rachel M Dick, Masahiro Fujita, Maarten Ooms, Lester S Manly

ACS Chem Neurosci· May 2020

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PET quantification of brain O-GlcNAcase with [F]LSN3316612 in healthy human volunteers.
Jae-Hoon Lee, Jeih-San Liow, Soumen Paul, Cheryl L Morse, Mohammad B Haskali, Lester Manly

EJNMMI Res· March 2020

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Late-onset Alzheimer disease risk variants mark brain regulatory loci.
Mariet Allen, Michaela Kachadoorian, Minerva M Carrasquillo, Aditya Karhade, Lester Manly

Neurol Genet· August 2015

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