Publications by authors named "Leszek Ignatowicz"

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Self and microbiota-derived epitopes induce CD4 T cell anergy and conversion into CD4Foxp3 regulatory cells.
Michal P Kuczma, Edyta A Szurek, Anna Cebula, Vu L Ngo, Maciej Pietrzak, Leszek Ignatowicz

Mucosal Immunol· March 2021

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IL-36R signaling integrates innate and adaptive immune-mediated protection against enteropathogenic bacteria.
Vu L Ngo, Hirohito Abo, Michal Kuczma, Edyta Szurek, Nora Moore, Leszek Ignatowicz

Proc Natl Acad Sci U S A· November 2020

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Bone Morphogenic Proteins Are Immunoregulatory Cytokines Controlling FOXP3 T Cells.
Lauren M Browning, Caroline Miller, Michal Kuczma, Maciej Pietrzak, Yu Jing, Leszek Ignatowicz

Cell Rep· October 2020

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Commensal epitopes drive differentiation of colonic T.
Michal P Kuczma, Edyta A Szurek, Anna Cebula, Benoit Chassaing, Yu-Jin Jung, Leszek Ignatowicz

Sci Adv· April 2020

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Dormant pathogenic CD4 T cells are prevalent in the peripheral repertoire of healthy mice.
Anna Cebula, Michal Kuczma, Edyta Szurek, Maciej Pietrzak, Natasha Savage, Leszek Ignatowicz

Nat Commun· October 2019

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TGF-β-mediated enhancement of T17 cell generation is inhibited by bone morphogenetic protein receptor 1α signaling.
Lauren M Browning, Maciej Pietrzak, Michal Kuczma, Colin P Simms, Agnieszka Kurczewska, Leszek Ignatowicz

Sci Signal· August 2018

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Non-canonicaly recruited TCRαβCD8αα IELs recognize microbial antigens.
Lukasz Wojciech, Edyta Szurek, Michal Kuczma, Anna Cebula, Wessam R Elhefnawy, Leszek Ignatowicz

Sci Rep· July 2018

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The mechanisms shaping the repertoire of CD4  Foxp3 regulatory T cells.
Piotr Kraj, Leszek Ignatowicz

Immunology· March 2018

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Anti-GITR Antibody Treatment Increases TCR Repertoire Diversity of Regulatory but not Effector T Cells Engaged in the Immune Response Against B16 Melanoma.
Bozena Scirka, Edyta Szurek, Maciej Pietrzak, Grzegorz Rempala, Pawel Kisielow, Leszek Ignatowicz

Arch Immunol Ther Exp (Warsz)· December 2017

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Differences in Expression Level of Helios and Neuropilin-1 Do Not Distinguish Thymus-Derived from Extrathymically-Induced CD4+Foxp3+ Regulatory T Cells.
Edyta Szurek, Anna Cebula, Lukasz Wojciech, Maciej Pietrzak, Grzegorz Rempala, Leszek Ignatowicz

PLoS One· June 2016

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Altered connexin 43 expression underlies age-dependent decrease of regulatory T cell suppressor function in nonobese diabetic mice.
Michal Kuczma, Cong-Yi Wang, Leszek Ignatowicz, Robert Gourdie, Piotr Kraj

J Immunol· June 2015

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Tregs strip dendritic cells of CD70 to regulate Th1 differentiation.
Lukasz Wojciech, Leszek Ignatowicz

EMBO J· May 2015

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The same self-peptide selects conventional and regulatory CD4⁺ T cells with identical antigen receptors.
Lukasz Wojciech, Alicja Ignatowicz, Michal Seweryn, Grzegorz Rempala, Simarjot Singh Pabla, Leszek Ignatowicz

Nat Commun· October 2014

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Segmented filamentous bacteria antigens presented by intestinal dendritic cells drive mucosal Th17 cell differentiation.
Yoshiyuki Goto, Casandra Panea, Gaku Nakato, Anna Cebula, Carolyn Lee, Leszek Ignatowicz

Immunity· April 2014

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Bayesian multivariate Poisson abundance models for T-cell receptor data.
Joshua Greene, Marc R Birtwistle, Leszek Ignatowicz, Grzegorz A Rempala

J Theor Biol· June 2013

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Thymus-derived regulatory T cells contribute to tolerance to commensal microbiota.
Anna Cebula, Michal Seweryn, Grzegorz A Rempala, Simarjot Singh Pabla, Richard A McIndoe, Leszek Ignatowicz

Nature· May 2013

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Carnitine deficiency in OCTN2-/- newborn mice leads to a severe gut and immune phenotype with widespread atrophy, apoptosis and a pro-inflammatory response.
Srinivas Sonne, Prem S Shekhawat, Dietrich Matern, Vadivel Ganapathy, Leszek Ignatowicz

PLoS One· April 2013

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Critical role of Bcl11b in suppressor function of T regulatory cells and prevention of inflammatory bowel disease.
Jeffrey Vanvalkenburgh, Diana I Albu, Chandra Bapanpally, Sarah Casanova, Danielle Califano, Leszek Ignatowicz

J Exp Med· September 2011

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Generation of T cell hybridomas from naturally occurring FoxP3+ regulatory T cells.
Nagendra Singh, Rafal Pacholczyk, Makio Iwashima, Leszek Ignatowicz

Methods Mol Biol· May 2011

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Model for comparative analysis of antigen receptor repertoires.
Grzegorz A Rempala, Michał Seweryn, Leszek Ignatowicz

J Theor Biol· January 2011

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Diversity of TCRs on natural Foxp3+ T cells in mice lacking Aire expression.
Danielle Daniely, Joanna Kern, Anna Cebula, Leszek Ignatowicz

J Immunol· June 2010

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Foxp3-deficient regulatory T cells do not revert into conventional effector CD4+ T cells but constitute a unique cell subset.
Michal Kuczma, Robert Podolsky, Nikhil Garge, Danielle Daniely, Rafal Pacholczyk, Leszek Ignatowicz

J Immunol· September 2009

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The specific T-cell response to antigenic peptides is influenced by bystander peptides.
Izabela Nowak, Elzbieta Pajtasz-Piasecka, Bartosz Chmielowski, Leszek Ignatowicz, Piotr Kuśnierczyk

Cell Mol Biol Lett· July 2009

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Nonself-antigens are the cognate specificities of Foxp3+ regulatory T cells.
Rafal Pacholczyk, Joanna Kern, Nagendra Singh, Makio Iwashima, Piotr Kraj, Leszek Ignatowicz

Immunity· September 2007

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Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells.
Rafal Pacholczyk, Hanna Ignatowicz, Piotr Kraj, Leszek Ignatowicz

Immunity· August 2006

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