Publications by authors named "Lewin Small"

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Cell-penetrant peptides as novel inhibitors of the interaction of coatomer protein COPB2/RACK2 with protein kinase Cε and cargo proteins.
Abisola A Olushola-Siedoks, Lewin Small, Kathryn J Fincham, Dorothy C C Wai, Dhruv Monteiro

Biochim Biophys Acta Mol Cell Res· January 2026

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An Ad Libitum-Fed Diet That Matches the Beneficial Lifespan Effects of Caloric Restriction but Acts via Opposite Effects on the Energy-Splicing Axis.
Amanda E Brandon, Tamara Pulpitel, Carsten Schmitz-Peiffer, Lewin Small, Alistair M Senior

Aging Cell· December 2025

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Dietary macronutrients modulate the proteome of brown adipose tissue in males and their female offspring.
Erin L Macartney, Alistair M Senior, Angela J Crean, Lewin Small, Lou Ruffino

Cell Rep· August 2025

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HIF1α mediates circadian regulation of skeletal muscle metabolism and substrate preference in response to time-of-day exercise.
Amy M Ehrlich, Kirstin A MacGregor, Stephen P Ashcroft, Lewin Small, Ali Altıntaş

Proc Natl Acad Sci U S A· July 2025

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Effects of a protein kinase C epsilon inhibitor on insulin signalling in lipid-treated HepG2 hepatocytes and glucose tolerance in fat-fed mice.
Miguel L Agoncillo, Zhongmin Gao, Harmannus C De Kraker, Stanton F McHardy, Robert O Messing, Lewin Small

Eur J Pharmacol· June 2025

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Insulin- and exercise-induced phosphoproteomics of human skeletal muscle identify REPS1 as a regulator of muscle glucose uptake.
Jeppe Kjærgaard, Cecilie B Lindqvist, Júlia Prats Quesada, Søren Jessen, Farina Schlabs, Lewin Small

Cell Rep Med· June 2025

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Liver proteomics identifies a disconnect between proteins associated with de novo lipogenesis and triglyceride storage.
Lewin Small, Tuong-Vi Nguyen, Mark Larance, Darren N Saunders, Andrew J Hoy

J Lipid Res· December 2024

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Seasonal light hours modulate peripheral clocks and energy metabolism in mice.
Lewin Small, Leonidas S Lundell, Jo Iversen, Amy M Ehrlich, Morten Dall

Cell Metab· October 2023

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SIRT3 overexpression in rat muscle does not ameliorate peripheral insulin resistance.
Brenna Osborne, Lauren E Wright, Amanda E Brandon, Ella Stuart, Lewin Small

J Endocrinol· September 2023

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β-cell function is regulated by metabolic and epigenetic programming of islet-associated macrophages, involving Axl, Mertk, and TGFβ receptor signaling.
Le May Thai, Liam O'Reilly, Saskia Reibe-Pal, Nancy Sue, Holly Holliday, Lewin Small

iScience· April 2023

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Insulin sensitivity is preserved in mice made obese by feeding a high starch diet.
Amanda E Brandon, Lewin Small, Tuong-Vi Nguyen, Eurwin Suryana, Henry Gong

Elife· November 2022

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Comparative analysis of sperm DNA methylation supports evolutionary acquired epigenetic plasticity for organ speciation.
Farideh Moharrek, Lars R Ingerslev, Ali Altıntaş, Leonidas Lundell, Ann N Hansen, Lewin Small

Epigenomics· November 2022

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Comparative analysis of oral and intraperitoneal glucose tolerance tests in mice.
Lewin Small, Amy Ehrlich, Jo Iversen, Stephen P Ashcroft, Kajetan Trošt

Mol Metab· March 2022

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Dynamic interplay between Afadin phosphorylation and diet regulates glucose homeostasis in obese mice.
Marco Tozzi, Erin L Brown, Patricia S S Petersen, Morten Lundh, Marie S Isidor, Lewin Small

J Physiol· February 2022

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Atlas of exercise metabolism reveals time-dependent signatures of metabolic homeostasis.
Shogo Sato, Kenneth A Dyar, Jonas T Treebak, Sara L Jepsen, Amy M Ehrlich, Lewin Small

Cell Metab· February 2022

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Ablation of DNA-methyltransferase 3A in skeletal muscle does not affect energy metabolism or exercise capacity.
Lewin Small, Lars R Ingerslev, Eleonora Manitta, Rhianna C Laker, Ann N Hansen

PLoS Genet· January 2021

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Contraction influences Per2 gene expression in skeletal muscle through a calcium-dependent pathway.
Lewin Small, Ali Altıntaş, Rhianna C Laker, Amy Ehrlich, Pattarawan Pattamaprapanont

J Physiol· December 2020

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Skeletal muscle enhancer interactions identify genes controlling whole-body metabolism.
Kristine Williams, Lars R Ingerslev, Jette Bork-Jensen, Martin Wohlwend, Ann Normann Hansen, Lewin Small

Nat Commun· June 2020

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Reduced insulin action in muscle of high fat diet rats over the diurnal cycle is not associated with defective insulin signaling.
Lewin Small, Amanda E Brandon, Benjamin L Parker, Vinita Deshpande, Azrah F Samsudeen

Mol Metab· July 2019

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Thermoneutral housing does not influence fat mass or glucose homeostasis in C57BL/6 mice.
Lewin Small, Henry Gong, Christian Yassmin, Gregory J Cooney, Amanda E Brandon

J Endocrinol· December 2018

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Acute activation of pyruvate dehydrogenase increases glucose oxidation in muscle without changing glucose uptake.
Lewin Small, Amanda E Brandon, Lake-Ee Quek, James R Krycer, David E James

Am J Physiol Endocrinol Metab· August 2018

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Fructose bisphosphatase 2 overexpression increases glucose uptake in skeletal muscle.
Ishita Bakshi, Eurwin Suryana, Lewin Small, Lake-Ee Quek, Amanda E Brandon

J Endocrinol· May 2018

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Modeling insulin resistance in rodents by alterations in diet: what have high-fat and high-calorie diets revealed?
Lewin Small, Amanda E Brandon, Nigel Turner, Gregory J Cooney

Am J Physiol Endocrinol Metab· March 2018

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Ablation of Grb10 Specifically in Muscle Impacts Muscle Size and Glucose Metabolism in Mice.
Lowenna J Holt, Amanda E Brandon, Lewin Small, Eurwin Suryana, Elaine Preston

Endocrinology· March 2018

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Grb10 deletion enhances muscle cell proliferation, differentiation and GLUT4 plasma membrane translocation.
Nancy Mokbel, Nolan J Hoffman, Christian M Girgis, Lewin Small, Nigel Turner

J Cell Physiol· November 2014

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