Publications by authors named "Lewis Becker"

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Insulin-like growth factor (IGF) and Insulin-like growth factor binding proteins (IGFBP) as predictors of type 2 diabetes risk in obese adults.
Priyanshi Maurya, Jun Yang, Allan Barnes, Lisa R Yanek, Lewis C Becker

J Diabetes Metab Disord· December 2025

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Threshold Effects, Cognitive Decline, and Longitudinal Changes in White Matter Hyperintensity Volume.
Sarvin Sasannia, Mykola Matsyuk, Shimeng Wang, Jinwei Zhang, Keenan A Walker, Lewis C Becker

medRxiv· December 2025

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Association of the Brain White Matter Hyperintensity with the Cognitive Performance in Middle-Aged Population.
Yousef Hannawi, Lisa R Yanek, Brian G Kral, Lewis C Becker, Dhananjay Vaidya

Cerebrovasc Dis· October 2025

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Genetic study of von Willebrand factor antigen levels ≤ 50 IU/dL identifies variants associated with increased risk of von Willebrand disease and bleeding.
Rachel K Friedman, Adam S Heath, Jennifer E Huffman, James T Baker, Natalie R Hasbani, Lewis C Becker

J Thromb Haemost· August 2025

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Rare damaging CCR2 variants are associated with lower lifetime cardiovascular risk.
Marios K Georgakis, Rainer Malik, Omar El Bounkari, Natalie R Hasbani, Jiang Li, Lewis C Becker

Genome Med· March 2025

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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.
Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, Fulong Yu, Jason Bacon, Lewis C Becker

Am J Hum Genet· February 2025

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Unveiling the Genetic Landscape of Coronary Artery Disease Through Common and Rare Structural Variants.
Kruthika R Iyer, Shoa L Clarke, Rodrigo Guarischi-Sousa, Ketrin Gjoni, Adam S Heath, Lewis C Becker

J Am Heart Assoc· February 2025

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General Kernel Machine Methods for Multi-Omics Integration and Genome-Wide Association Testing With Related Individuals.
Amarise Little, Ni Zhao, Anna Mikhaylova, Angela Zhang, Wodan Ling, Lewis Becker

Genet Epidemiol· January 2025

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Whole-genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.
Jennifer E Huffman, Jayna Nicholas, Julie Hahn, Adam S Heath, Laura M Raffield, Lewis C Becker

Blood· November 2024

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Rare variant contribution to the heritability of coronary artery disease.
Ghislain Rocheleau, Shoa L Clarke, Gaëlle Auguste, Natalie R Hasbani, Alanna C Morrison, Lewis C Becker

Nat Commun· October 2024

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Longitudinal decline in peak V̇o with aging in a healthy population is associated with a reduction in peripheral oxygen utilization but not in cardiac output.
Majd AlGhatrif, Christopher H Morrell, Jerome L Fleg, Paul D Chantler, Samer S Najjar, Lewis C Becker

Am J Physiol Heart Circ Physiol· August 2024

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Rare damaging variants are associated with lower lifetime cardiovascular risk.
Marios K Georgakis, Rainer Malik, Omar El Bounkari, Natalie R Hasbani, Jiang Li, Lewis C Becker

medRxiv· June 2024

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A genetic association study of circulating coagulation factor VIII and von Willebrand factor levels.
Paul S de Vries, Paula Reventun, Michael R Brown, Adam S Heath, Jennifer E Huffman, Lewis C Becker

Blood· May 2024

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Validation of human telomere length multi-ancestry meta-analysis association signals identifies POP5 and KBTBD6 as human telomere length regulation genes.
Rebecca Keener, Surya B Chhetri, Carla J Connelly, Margaret A Taub, Matthew P Conomos, Lewis C Becker

Nat Commun· May 2024

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Genomic and phenotypic correlates of mosaic loss of chromosome Y in blood.
Yasminka A Jakubek, Xiaolong Ma, Adrienne M Stilp, Fulong Yu, Jason Bacon, Lewis C Becker

medRxiv· April 2024

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Type 2 Diabetes Modifies the Association of CAD Genomic Risk Variants With Subclinical Atherosclerosis.
Natalie R Hasbani, Kenneth E Westerman, Soo Heon Kwak, Han Chen, Xihao Li, Lewis C Becker

Circ Genom Precis Med· December 2023

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Whole-genome sequencing uncovers two loci for coronary artery calcification and identifies ARSE as a regulator of vascular calcification.
Paul S de Vries, Matthew P Conomos, Kuldeep Singh, Christopher J Nicholson, Deepti Jain, Lewis C Becker

Nat Cardiovasc Res· December 2023

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Multi-ancestry genome-wide study identifies effector genes and druggable pathways for coronary artery calcification.
Maryam Kavousi, Maxime M Bos, Hanna J Barnes, Christian L Lino Cardenas, Doris Wong, Diane M Becker, Lewis C Becker

Nat Genet· October 2023

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Whole genome analysis of plasma fibrinogen reveals population-differentiated genetic regulators with putative liver roles.
Jennifer E Huffman, Jayna Nicolas, Julie Hahn, Adam S Heath, Laura M Raffield, Lewis C Becker

medRxiv· June 2023

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Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis.
Joshua S Weinstock, Jayakrishnan Gopakumar, Bala Bharathi Burugula, Md Mesbah Uddin, Nikolaus Jahn, Lewis C Becker

Nature· April 2023

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The genetic determinants of recurrent somatic mutations in 43,693 blood genomes.
Joshua S Weinstock, Cecelia A Laurie, Jai G Broome, Kent D Taylor, Xiuqing Guo, Lewis C Becker

Sci Adv· April 2023

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Whole genome sequencing identifies structural variants contributing to hematologic traits in the NHLBI TOPMed program.
Marsha M Wheeler, Adrienne M Stilp, Shuquan Rao, Bjarni V Halldórsson, Doruk Beyter, Lewis C Becker

Nat Commun· December 2022

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Rare Variants in Genes Encoding Subunits of the Epithelial Na Channel Are Associated With Blood Pressure and Kidney Function.
Brandon M Blobner, Annet Kirabo, Ossama B Kashlan, Shaohu Sheng, Donna K Arnett, Lewis C Becker

Hypertension· November 2022

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Insights From a Large-Scale Whole-Genome Sequencing Study of Systolic Blood Pressure, Diastolic Blood Pressure, and Hypertension.
Tanika N Kelly, Xiao Sun, Karen Y He, Michael R Brown, Sarah A Gagliano Taliun, Lewis C Becker

Hypertension· August 2022

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Association of Vascular Properties With the Brain White Matter Hyperintensity in Middle-Aged Population.
Yousef Hannawi, Dhananjay Vaidya, Lisa R Yanek, Michelle C Johansen, Brian G Kral, Lewis C Becker, Diane M Becker

J Am Heart Assoc· June 2022

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