Publications by authors named "Lewis Sheiner"

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Improving data reliability using a non-compliance detection method versus using pharmacokinetic criteria.
Smita A Kshirsagar, Terrence F Blaschke, Lewis B Sheiner, M Krygowski, Edward P Acosta

J Pharmacokinet Pharmacodyn· February 2007

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Population pharmacokinetics of nicotine and its metabolites I. Model development.
Micha Levi, Delia A Dempsey, Neal L Benowitz, Lewis B Sheiner

J Pharmacokinet Pharmacodyn· February 2007

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Prediction methods for nicotine clearance using cotinine and 3-hydroxy-cotinine spot saliva samples II. Model application.
Micha Levi, Delia A Dempsey, Neal L Benowitz, Lewis B Sheiner

J Pharmacokinet Pharmacodyn· February 2007

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Diagnostics for confounding in PK/PD models for oxcarbazepine.
Jerry R Nedelman, Donald B Rubin, Lewis B Sheiner

Stat Med· January 2007

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Analyzing multi-response data using forcing functions.
Liping Zhang, Lewis B Sheiner

J Pharmacokinet Pharmacodyn· April 2005

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Getting the Dose Right: report from the Tenth European Federation of Pharmaceutical Sciences (EUFEPS) conference on optimizing drug development.
Donald R Stanski, Malcolm Rowland, Lewis B Sheiner

J Pharmacokinet Pharmacodyn· April 2005

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Estimating treatment effect in the presence of non-compliance measured with error: precision and robustness of data analysis methods.
Leslie A Kenna, Lewis B Sheiner

Stat Med· December 2004

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Population one-compartment pharmacokinetic analysis with missing dosage data.
Dolors Soy, Stuart L Beal, Lewis B Sheiner

Clin Pharmacol Ther· November 2004

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Population pharmacokinetics of enfuvirtide in pediatric patients with human immunodeficiency virus: searching for exposure-response relationships.
Dolors Soy, Francesca T Aweeka, Joseph A Church, Coleen K Cunningham, Paul Palumbo, Lewis B Sheiner

Clin Pharmacol Ther· December 2003

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Simultaneous vs. sequential analysis for population PK/PD data I: best-case performance.
Liping Zhang, Stuart L Beal, Lewis B Sheiner

J Pharmacokinet Pharmacodyn· December 2003

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Hypothesis: a single clinical trial plus causal evidence of effectiveness is sufficient for drug approval.
Carl C Peck, Donald B Rubin, Lewis B Sheiner

Clin Pharmacol Ther· June 2003

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Effect of simultaneous versus staggered dosing on pharmacokinetic interactions of protease inhibitors.
Carla B Washington, Charles Flexner, Lewis B Sheiner, Susan L Rosenkranz, Yoninah Segal

Clin Pharmacol Ther· May 2003

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Pharmacokinetic-pharmacodynamic modelling of magnesium plasma concentration and blood pressure in preeclamptic women.
Jianfeng Lu, Marc Pfister, Paolo Ferrari, Gang Chen, Lewis Sheiner

Clin Pharmacokinet· April 2003

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Population pharmacokinetics and pharmacodynamics of efavirenz, nelfinavir, and indinavir: Adult AIDS Clinical Trial Group Study 398.
Marc Pfister, Line Labbé, Scott M Hammer, John Mellors, Kara K Bennett, Lewis B Sheiner

Antimicrob Agents Chemother· January 2003

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Modeling of transfer kinetics at the serum-cerebrospinal fluid barrier in rabbits with experimental meningitis: application to grepafloxacin.
Marc Pfister, Liping Zhang, Margareta Hammarlund-Udenaes, Lewis B Sheiner, Cynthia M Gerber

Antimicrob Agents Chemother· January 2003

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Model-based analysis of the pharmacokinetic interactions between ritonavir, nelfinavir, and saquinavir after simultaneous and staggered oral administration.
Jian-Feng Lu, Terrence F Blaschke, Charles Flexner, Susan L Rosenkranz, Lewis B Sheiner

Drug Metab Dispos· December 2002

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More efficient clinical trials through use of scientific model-based statistical tests.
E Niclas Jonsson, Lewis B Sheiner

Clin Pharmacol Ther· December 2002

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Effect of coadministration of nelfinavir, indinavir, and saquinavir on the pharmacokinetics of amprenavir.
Marc Pfister, Line Labbé, Jian-Feng Lu, Scott M Hammer, John Mellors, Lewis B Sheiner

Clin Pharmacol Ther· August 2002

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Is intent-to-treat analysis always (ever) enough?
Lewis B Sheiner

Br J Clin Pharmacol· August 2002

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Dual vs single protease inhibitor therapy following antiretroviral treatment failure: a randomized trial.
Scott M Hammer, Florin Vaida, Kara K Bennett, Mary K Holohan, Lewis Sheiner

JAMA· July 2002

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Determination of maximum effect.
Lewis B Sheiner, Nicholas H G Holford

Clin Pharmacol Ther· April 2002

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Reply.
Lewis B. Sheiner, Donald B. Rubin

Clin Pharmacol Ther· December 2000

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