Publications by authors named "Li-Guang Lou"

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HER3 upregulation reduces DS-8201 sensitivity in HER2-positive tumor cells by ATR/CHK1/FoxO1 signaling cascade.
Wen-Jing Li, Kai-Ge Kang, Yu-Xiang Zhang, Xin-Xin Zhao, Xi Zhu, Li-Guang Lou

Acta Pharmacol Sin· September 2025

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SIBP-03, a novel anti-HER3 antibody, exerts antitumor effects and synergizes with EGFR- and HER2-targeted drugs.
Wen-Jing Li, Cheng-Ying Xie, Xi Zhu, Jiao Tang, Lei Wang, Li-Guang Lou

Acta Pharmacol Sin· April 2024

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Author Correction: DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer.
Xiang-Ling Chen, Peng Liu, Wei-Liang Zhu, Li-Guang Lou

Acta Pharmacol Sin· March 2024

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Design and Synthesis of Cyclolipopeptide Mimics of Dysoxylactam A and Evaluation of the Reversing Potencies against P-Glycoprotein-Mediated Multidrug Resistance.
Guan-Zhou Yang, Lei Wang, Kun Gao, Xi Zhu, Li-Guang Lou

J Med Chem· March 2024

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DCZ5248, a novel dual inhibitor of Hsp90 and autophagy, exerts antitumor activity against colon cancer.
Xiang-Ling Chen, Peng Liu, Wei-Liang Zhu, Li-Guang Lou

Acta Pharmacol Sin· January 2021

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SHR-A1403, a novel c-Met antibody-drug conjugate, exerts encouraging anti-tumor activity in c-Met-overexpressing models.
Chang-Yong Yang, Lei Wang, Xing Sun, Mi Tang, Hai-Tian Quan, Li-Guang Lou

Acta Pharmacol Sin· July 2019

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Dysoxylactam A: A Macrocyclolipopeptide Reverses P-Glycoprotein-Mediated Multidrug Resistance in Cancer Cells.
Cui-Ping Liu, Cheng-Ying Xie, Jin-Xin Zhao, Kai-Long Ji, Xin-Xiang Lei, Li-Guang Lou

J Am Chem Soc· May 2019

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Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma.
Ming-Zhao Gao, Hong-Bin Wang, Xiang-Ling Chen, Wen-Ting Cao, Li Fu, Li-Guang Lou

Acta Pharmacol Sin· February 2019

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Synthesis and antitumor activity of a series of lactone-opened camptothecin derivatives.
Chao Zheng, Ming-Zong Li, Tian-Pa You, Wei-Ping Tang, Li-Guang Lou

J Asian Nat Prod Res· January 2019

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Pharmacokinetics and disposition of anlotinib, an oral tyrosine kinase inhibitor, in experimental animal species.
Chen-Chun Zhong, Feng Chen, Jun-Ling Yang, Wei-Wei Jia, Li Li, Li-Guang Lou

Acta Pharmacol Sin· June 2018

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Unusual Cytotoxic Steroidal Saponins from the Gorgonian Astrogorgia dumbea.
Ya-Nan Lu, Ping Cui, Xiao-Qing Tian, Li-Guang Lou, Cheng-Qi Fan

Planta Med· June 2016

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Preclinical activity of lobaplatin as a single agent and in combination with taxanes for ovarian carcinoma cells.
Xu Sun, Li-Guang Lou, Dong-Hu Sui, Xiao-Hua Wu

Asian Pac J Cancer Prev· August 2015

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Curcumin derivative C817 inhibits proliferation of imatinib-resistant chronic myeloid leukemia cells with wild-type or mutant Bcr-Abl in vitro.
Li-xian Wu, Ying Wu, Rui-jia Chen, Yang Liu, Li-sen Huang, Li-guang Lou

Acta Pharmacol Sin· March 2014

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Antitumor activity of lobaplatin alone or in combination with antitubulin agents in non-small-cell lung cancer.
Cheng-Ying Xie, Yong-Ping Xu, Wei Jin, Li-Guang Lou

Anticancer Drugs· August 2012

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A novel and simple hollow-fiber assay for in vivo evaluation of nonpeptidyl thrombopoietin receptor agonists.
Cheng-Ying Xie, Yong-Ping Xu, Hong-Bing Zhao, Li-Guang Lou

Exp Hematol· May 2012

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Three new 18-oxygenated ent-kaurane diterpenoids from Isodon leucophyllus.
Hai Bo Zhang, Jian Xin Pu, Yong Zhao, Fei He, Wei Zhao, Li Guang Lou

Nat Prod Commun· December 2010

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Structure and cytotoxicity of diterpenoids from Isodon eriocalyx.
Xiao-Nian Li, Jian-Xin Pu, Xue Du, Li-Guang Lou, Li-Mei Li

J Nat Prod· November 2010

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Synthesis and structure-activity relationship studies of cytotoxic anhydrovinblastine amide derivatives.
Yong Shao, Han-Kun Zhang, Hong Ding, Hai-Tian Quan, Li-Guang Lou

J Nat Prod· June 2009

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Design, synthesis and biological evaluation of novel fluorinated docetaxel analogues.
Hong-Fu Lu, Xun Sun, Liang Xu, Li-Guang Lou, Guo-Qiang Lin

Eur J Med Chem· February 2009

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Cytotoxic triterpenoid saponins from Vaccaria segetalis.
Chun-Hui Ma, Ming-Song Fan, Li-Ping Lin, Wei-Dong Tang, Li-Guang Lou

J Asian Nat Prod Res· September 2008

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Synthesis and anticancer activity of lipophilic platinum(II) complexes of 3,5-diisopropylsalicylate.
Yao Yu, Li-Guang Lou, Wei-Ping Liu, Hua-Jie Zhu, Qing-Song Ye

Eur J Med Chem· July 2008

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Kadcoccilactones A-J, triterpenoids from Kadsura coccinea.
Xue-Mei Gao, Jian-Xin Pu, Sheng-Xiong Huang, Yang Lu, Li-Guang Lou

J Nat Prod· July 2008

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Synthesis, cytotoxic activity, and SAR analysis of the derivatives of taxchinin A and brevifoliol.
Yu Zhao, Na Guo, Li-Guang Lou, Yu-Wen Cong, Li-Yan Peng

Bioorg Med Chem· May 2008

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Synthesis and cytotoxicity of platinum(II) complexes of a physiologically active carrier histamine.
Xi-Zhu Chen, Qing-Song Ye, Li-Guang Lou, Ming-Jin Xie, Wei-Ping Liu

Arch Pharm (Weinheim)· February 2008

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Isolation and structure elucidation of kadlongilactones C-F from Kadsura longipedunculata by NMR spectroscopy and DFT computational methods.
Jian-Xin Pu, Sheng-Xiong Huang, Jie Ren, Wei-Lie Xiao, Li-Mei Li, Li-Guang Lou

J Nat Prod· November 2007

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