Publications by authors named "Li-Rong Shao"

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Altered synaptic functions in a humanized mouse model of down syndrome (TcMAC21): Implications for seizure susceptibility.
Li-Rong Shao, Carl E Stafstrom

Epilepsy Res· December 2025

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Increased seizure susceptibility and neocortical excitability in TcMAC21 Down syndrome mice.
Viveka Chinnasamy, Carl E Stafstrom, Li-Rong Shao

Neuroscience· October 2025

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Treatment efficacy for infantile epileptic spasms syndrome in children with trisomy 21.
Henry Chen, Adam L Numis, Renée A Shellhaas, John R Mytinger, Debopam Samanta, Li-Rong Shao

Front Pediatr· February 2025

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Infantile Spasms in Pediatric Down Syndrome: Potential Mechanisms Driving Therapeutic Considerations.
Carl E Stafstrom, Li-Rong Shao

Children (Basel)· December 2024

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Increased propensity for infantile spasms and altered neocortical excitation-inhibition balance in a mouse model of down syndrome carrying human chromosome 21.
Li-Rong Shao, Feng Gao, Viveka Chinnasamy, Yasuhiro Kazuki, Mistuo Oshimura

Neurobiol Dis· August 2023

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Antiseizure effect of 2-deoxyglucose is not dependent on the presynaptic vacuole ATP pump or the somatic ATP-sensitive K channel.
Li-Rong Shao, Remi Janicot, Carl E Stafstrom

J Neurophysiol· June 2023

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Enhanced burst discharges in the CA1 area of the immature versus adult hippocampus: patterns and cellular mechanisms.
Li-Rong Shao, F Edward Dudek

J Neurophysiol· December 2022

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2-deoxyglucose and β-hydroxybutyrate fail to attenuate seizures in the betamethasone-NMDA model of infantile spasms.
Remi Janicot, Li-Rong Shao, Carl E Stafstrom

Epilepsia Open· March 2022

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Targeting ischemia-induced KCC2 hypofunction rescues refractory neonatal seizures and mitigates epileptogenesis in a mouse model.
Brennan J Sullivan, Pavel A Kipnis, Brandon M Carter, Li-Rong Shao, Shilpa D Kadam

Sci Signal· November 2021

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Na-K-ATPase functions in the developing hippocampus: regional differences in CA1 and CA3 neuronal excitability and role in epileptiform network bursting.
Li-Rong Shao, Remi Janicot, Carl E Stafstrom

J Neurophysiol· January 2021

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The efficacy of fructose-1,6-bisphosphate in suppressing status epilepticus in developing rats.
Remi Janicot, Carl E Stafstrom, Li-Rong Shao

Epilepsy Res· December 2020

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2-Deoxyglucose terminates pilocarpine-induced status epilepticus in neonatal rats.
Remi Janicot, Carl E Stafstrom, Li-Rong Shao

Epilepsia· July 2020

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Infantile Spasms: An Update on Pre-Clinical Models and EEG Mechanisms.
Remi Janicot, Li-Rong Shao, Carl E Stafstrom

Children (Basel)· January 2020

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2-Deoxyglucose and Beta-Hydroxybutyrate: Metabolic Agents for Seizure Control.
Jong M Rho, Li-Rong Shao, Carl E Stafstrom

Front Cell Neurosci· April 2019

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Pediatric Epilepsy Mechanisms: Expanding the Paradigm of Excitation/Inhibition Imbalance.
Li-Rong Shao, Christa W Habela, Carl E Stafstrom

Children (Basel)· February 2019

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Glycolytic inhibition: A novel approach toward controlling neuronal excitability and seizures.
Li-Rong Shao, Jong M Rho, Carl E Stafstrom

Epilepsia Open· December 2018

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The Glycolytic Metabolite, Fructose-1,6-bisphosphate, Blocks Epileptiform Bursts by Attenuating Voltage-Activated Calcium Currents in Hippocampal Slices.
Li-Rong Shao, Guangxin Wang, Carl E Stafstrom

Front Cell Neurosci· June 2018

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Glycolytic inhibition by 2-deoxy-d-glucose abolishes both neuronal and network bursts in an in vitro seizure model.
Li-Rong Shao, Carl E Stafstrom

J Neurophysiol· July 2017

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Pediatric Epileptic Encephalopathies: Pathophysiology and Animal Models.
Li-Rong Shao, Carl E Stafstrom

Semin Pediatr Neurol· May 2016

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Synaptic and extrasynaptic plasticity in glutamatergic circuits involving dentate granule cells following chronic N-methyl-D-aspartate receptor inhibition.
Shuijin He, Li-Rong Shao, Yu Wang, Suzanne B Bausch

J Neurophysiol· March 2013

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Increased Kv1 channel expression may contribute to decreased sIPSC frequency following chronic inhibition of NR2B-containing NMDAR.
Shuijin He, Li-Rong Shao, W Bradley Rittase, Suzanne B Bausch

Neuropsychopharmacology· May 2012

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Repetitive perforant-path stimulation induces epileptiform bursts in minislices of dentate gyrus from rats with kainate-induced epilepsy.
Li-Rong Shao, F Edward Dudek

J Neurophysiol· February 2011

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Both synaptic and intrinsic mechanisms underlie the different properties of population bursts in the hippocampal CA3 area of immature versus adult rats.
Li-Rong Shao, F Edward Dudek

J Physiol· December 2009

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Changes in mIPSCs and sIPSCs after kainate treatment: status epilepticus-induced neuronal loss or direct activation of kainate receptors?
Li-Rong Shao, F Edward Dudek

J Neurophysiol· August 2006

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Mossy fiber sprouting and recurrent excitation: direct electrophysiologic evidence and potential implications.
F Edward Dudek, Li-Rong Shao

Epilepsy Curr· October 2005

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