Publications by authors named "Li-Yu Sung"

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Combining orthogonal CRISPR and CRISPRi systems for genome engineering and metabolic pathway modulation in Escherichia coli.
Li-Yu Sung, Meng-Ying Wu, Mei-Wei Lin, Mu-Nung Hsu, Vu Anh Truong

Biotechnol Bioeng· May 2019

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Combining CRISPR and CRISPRi Systems for Metabolic Engineering of E. coli and 1,4-BDO Biosynthesis.
Meng-Ying Wu, Li-Yu Sung, Hung Li, Chun-Hung Huang, Yu-Chen Hu

ACS Synth Biol· December 2017

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Improved calvarial bone repair by hASCs engineered with Cre/loxP-based baculovirus conferring prolonged BMP-2 and MiR-148b co-expression.
Kuei-Chang Li, Shih-Chun Lo, Li-Yu Sung, Ya-Hsin Liao, Yu-Han Chang

J Tissue Eng Regen Med· November 2017

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Enhancing Protein Production Yield from Chinese Hamster Ovary Cells by CRISPR Interference.
Chih-Che Shen, Li-Yu Sung, Shih-Yeh Lin, Mei-Wei Lin, Yu-Chen Hu

ACS Synth Biol· August 2017

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Enhanced critical-size calvarial bone healing by ASCs engineered with Cre/loxP-based hybrid baculovirus.
Shih-Chun Lo, Kuei-Chang Li, Yu-Han Chang, Mu-Nung Hsu, Li-Yu Sung

Biomaterials· April 2017

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Enhanced integration of large DNA into E. coli chromosome by CRISPR/Cas9.
Mu-En Chung, I-Hsin Yeh, Li-Yu Sung, Meng-Ying Wu, Yun-Peng Chao

Biotechnol Bioeng· January 2017

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CRISPR-Cas9 for the genome engineering of cyanobacteria and succinate production.
Hung Li, Claire R Shen, Chun-Hung Huang, Li-Yu Sung, Meng-Ying Wu

Metab Eng· November 2016

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CRISPR interference (CRISPRi) for gene regulation and succinate production in cyanobacterium S. elongatus PCC 7942.
Chun-Hung Huang, Claire R Shen, Hung Li, Li-Yu Sung, Meng-Ying Wu

Microb Cell Fact· November 2016

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Healing of massive segmental femoral bone defects in minipigs by allogenic ASCs engineered with FLPo/Frt-based baculovirus vectors.
Chin-Yu Lin, Yao-Horng Wang, Kuei-Chang Li, Li-Yu Sung, Chia-Lin Yeh

Biomaterials· May 2015

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Efficient gene delivery into cell lines and stem cells using baculovirus.
Li-Yu Sung, Chiu-Ling Chen, Shih-Yeh Lin, Kuei-Chang Li, Chia-Lin Yeh

Nat Protoc· August 2014

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Osteogenic differentiation of adipose-derived stem cells and calvarial defect repair using baculovirus-mediated co-expression of BMP-2 and miR-148b.
Ya-Hsin Liao, Yu-Han Chang, Li-Yu Sung, Kuei-Chang Li, Chia-Lin Yeh

Biomaterials· June 2014

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Long-term tracking of segmental bone healing mediated by genetically engineered adipose-derived stem cells: focuses on bone remodeling and potential side effects.
Chin-Yu Lin, Yu-Han Chang, Li-Yu Sung, Chiu-Ling Chen, Shih-Yeh Lin

Tissue Eng Part A· May 2014

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Regenerating cartilages by engineered ASCs: prolonged TGF-β3/BMP-6 expression improved articular cartilage formation and restored zonal structure.
Chia-Hsin Lu, Tsung-Szu Yeh, Chia-Lin Yeh, Yu-Hua Dean Fang, Li-Yu Sung

Mol Ther· January 2014

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The use of ASCs engineered to express BMP2 or TGF-β3 within scaffold constructs to promote calvarial bone repair.
Chin-Yu Lin, Yu-Han Chang, Kuei-Chang Li, Chia-Hsin Lu, Li-Yu Sung

Biomaterials· December 2013

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Enhanced and prolonged baculovirus-mediated expression by incorporating recombinase system and in cis elements: a comparative study.
Li-Yu Sung, Chiu-Ling Chen, Shih-Yeh Lin, Shiaw-Min Hwang, Chia-Hsin Lu

Nucleic Acids Res· August 2013

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Immune responses during healing of massive segmental femoral bone defects mediated by hybrid baculovirus-engineered ASCs.
Chin-Yu Lin, Kun-Ju Lin, Kuei-Chang Li, Li-Yu Sung, Swei Hsueh

Biomaterials· October 2012

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Simultaneous induction of autophagy and toll-like receptor signaling pathways by graphene oxide.
Guan-Yu Chen, Hong-Jie Yang, Chia-Hsin Lu, Yu-Chan Chao, Shiaw-Min Hwang, Li-Yu Sung

Biomaterials· September 2012

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Augmented healing of critical-size calvarial defects by baculovirus-engineered MSCs that persistently express growth factors.
Chin-Yu Lin, Yu-Han Chang, Chun-Yu Kao, Chia-Hsin Lu, Li-Yu Sung

Biomaterials· May 2012

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Development of hybrid baculovirus vectors for artificial MicroRNA delivery and prolonged gene suppression.
Chiu-Ling Chen, Wen-Yi Luo, Wen-Hsin Lo, Kun-Ju Lin, Li-Yu Sung

Biotechnol Bioeng· December 2011

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Baculovirus as a gene delivery vector for cartilage and bone tissue engineering.
Chin-Yu Lin, Chia-Hsin Lu, Wen-Yi Luo, Yu-Han Chang, Li-Yu Sung

Curr Gene Ther· June 2010

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Xenotransplantation of human mesenchymal stem cells into immunocompetent rats for calvarial bone repair.
Ching-Kuang Chuang, Kun-Ju Lin, Chin-Yu Lin, Yu-Han Chang, Tzu-Chen Yen, Li-Yu Sung

Tissue Eng Part A· February 2010

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Baculovirus-mediated growth factor expression in dedifferentiated chondrocytes accelerates redifferentiation: effects of combinational transduction.
Li-Yu Sung, Hsin-Yi Chiu, Huang-Chi Chen, Yen-Lin Chen, Ching-Kuang Chuang

Tissue Eng Part A· June 2009

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The repair of osteochondral defects using baculovirus-mediated gene transfer with de-differentiated chondrocytes in bioreactor culture.
Huang-Chi Chen, Yu-Han Chang, Ching-Kuang Chuang, Chin-Yu Lin, Li-Yu Sung

Biomaterials· February 2009

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Modulation of chondrocyte phenotype via baculovirus-mediated growth factor expression.
Li-Yu Sung, Wen-Hsin Lo, Hsin-Yi Chiu, Huang-Chi Chen, Ching-Kuang Chung

Biomaterials· August 2007

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Composite chondroitin-6-sulfate/dermatan sulfate/chitosan scaffolds for cartilage tissue engineering.
Yen-Lin Chen, Hsiao-Ping Lee, Hing-Yuen Chan, Li-Yu Sung, Huang-Chi Chen

Biomaterials· May 2007

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