Publications by authors named "Liangning Hu"

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PFKL Inhibition by DT-13: A Novel Approach to Combat Hepatocellular Carcinoma.
Qiang Yu, Liangning Hu, Chenfei Tan, Min Gao, Zhenzhen Wen

Int J Hepatol· January 2026

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Editor's Note: A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Yingcong Wang, Jing Huang, Bo Li, Han Xue, Guido Tricot, Liangning Hu, Shuaikang Chang, Fenghuang Zhan, Weiliang Zhu

Cancer Res· August 2025

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KDM6A Deficiency Induces Myeloid Bias and Promotes CMML-Like Disease Through JAK/STAT3 Activation by Repressing SOCS3.
Huiqiao Chen, Shufen Wang, Ruoyu Dong, Pinhui Yu, Tianyu Li, Liangning Hu

Adv Sci (Weinh)· June 2025

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Prognostic value of peripheral eosinophil counts in patients with newly diagnosed multiple myeloma.
Xu Chen, Xiaoyan Yue, Hao Jiang, Qianqian Yang, Jinwen Huang, Liangning Hu

Cancer Biol Med· May 2025

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Association between the pre-transplantation serum ferritin level and outcomes of hematopoietic stem cell transplantation: A systematic review and meta-analysis.
Wenjue Pan, Qibei Teng, Huiqiao Chen, Liangning Hu, Xiaoyan Yue, Shufen Wang

Heliyon· September 2024

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EZH2 inhibition induces senescence via ERK1/2 signaling pathway in multiple myeloma.
Shushan Guo, Qiongwei Tang, Xuejie Gao, Liangning Hu, Ke Hu, Hui Zhang, Zhuning Wang, Shuaikang Chang, Huifang Hu

Acta Biochim Biophys Sin (Shanghai)· May 2024

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The association of intestinal microbiota diversity and outcomes of allogeneic hematopoietic cell transplantation: a systematic review and meta-analysis.
Shufen Wang, Xiaoyan Yue, Hongyu Zhou, Xu Chen, Huiqiao Chen, Liangning Hu

Ann Hematol· December 2023

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A novel M phase blocker, DCZ3301 enhances the sensitivity of bortezomib in resistant multiple myeloma through DNA damage and mitotic catastrophe.
Liangning Hu, Bo Li, Gege Chen, Dongliang Song, Zhijian Xu, Hui Zhang, Weiliang Zhu

J Exp Clin Cancer Res· June 2020

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A novel phosphoramide compound, DCZ0847, displays in vitro and in vivo anti-myeloma activity, alone or in combination with bortezomib.
Gege Chen, Ke Hu, Haiguo Sun, Jinfeng Zhou, Dongliang Song, Hui Zhang, Liangning Hu, Weiliang Zhu

Cancer Lett· May 2020

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Novel cyclophosphamide of natural products osalmide and pterostilbene induces cytotoxicity and cell cycle arrest in diffuse large B-cell lymphoma cells.
Mengyu Xi, Wan He, Bo Li, Jinfeng Zhou, Zhijian Xu, Huiqun Wu, Liangning Hu, Shuaikang Chang, Weiliang Zhu

Acta Biochim Biophys Sin (Shanghai)· April 2020

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A novel silicone derivative of natural osalmid (DCZ0858) induces apoptosis and cell cycle arrest in diffuse large B-cell lymphoma via the JAK2/STAT3 pathway.
Kang Lu, Bo Li, Hui Zhang, Zhijian Xu, Dongliang Song, Liangning Hu, Weiliang Zhu

Signal Transduct Target Ther· April 2020

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A Small-Molecule Inhibitor Targeting TRIP13 Suppresses Multiple Myeloma Progression.
Yingcong Wang, Jing Huang, Bo Li, Han Xue, Guido Tricot, Liangning Hu, Shuaikang Chang, Fenghuang Zhan, Weiliang Zhu

Cancer Res· February 2020

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Antitumor effects of rafoxanide in diffuse large B cell lymphoma via the PTEN/PI3K/Akt and JNK/c-Jun pathways.
Wan He, Zhijian Xu, Dongliang Song, Hui Zhang, Bo Li, Liangning Hu, Weiliang Zhu

Life Sci· February 2020

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Ferroportin downregulation promotes cell proliferation by modulating the Nrf2-miR-17-5p axis in multiple myeloma.
Yuanyuan Kong, Liangning Hu, Kang Lu, Yingcong Wang, Yongsheng Xie, Huiqun Wu, Fenghuang Zhan

Cell Death Dis· August 2019

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DCZ0801, a novel compound, induces cell apoptosis and cell cycle arrest via MAPK pathway in multiple myeloma.
Ting Zhang, Bo Li, Qilin Feng, Zhijian Xu, Cheng Huang, Huiqun Wu, Liangning Hu, Hui Zhang, Weiliang Zhu

Acta Biochim Biophys Sin (Shanghai)· May 2019

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DCZ0814 induces apoptosis and G0/G1 phase cell cycle arrest in myeloma by dual inhibition of mTORC1/2.
Yuanyuan Kong, Bo Li, Shuaikang Chang, Lu Gao, Zhijian Xu, Liangning Hu, Weiliang Zhu

Cancer Manag Res· May 2019

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Targeting the PI3K/Akt/mTOR signaling pathway by pterostilbene attenuates mantle cell lymphoma progression.
Dandan Yu, Yong Zhang, Gege Chen, Yongsheng Xie, Zhijian Xu, Shuaikang Chang, Liangning Hu, Weiliang Zhu

Acta Biochim Biophys Sin (Shanghai)· August 2018

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Preclinical activity of DCZ3301, a novel aryl-guanidino compound in the therapy of multiple myeloma.
Minjie Gao, Bo Li, Xi Sun, Yunfei Zhou, Yingcong Wang, Huiqun Wu, Liangning Hu, Weiliang Zhu

Theranostics· June 2018

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Dual inhibition of mTORC1/2 by DCZ0358 induces cytotoxicity in multiple myeloma and overcomes the protective effect of the bone marrow microenvironment.
Lu Gao, Bo Li, Guang Yang, Peng Liu, Xiucai Lan, Shuaikang Chang, Liangning Hu, Weiliang Zhu

Cancer Lett· May 2018

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Pterostilbene Induces Cell Apoptosis and Cell Cycle Arrest in T-Cell Leukemia/Lymphoma by Suppressing the ERK1/2 Pathway.
Gaomei Chang, Wenqin Xiao, Zhijian Xu, Dandan Yu, Bo Li, Shuaikang Chang, Liangning Hu, Weiliang Zhu

Biomed Res Int· April 2018

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PKC inhibition of sotrastaurin has antitumor activity in diffuse large B-cell lymphoma via regulating the expression of MCT-1.
Gaomei Chang, Jiayi Zheng, Wenqin Xiao, Shuaikang Chang, Qing Wei, Huiqun Wu, Liangning Hu

Acta Biochim Biophys Sin (Shanghai)· April 2018

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DCZ3301, a novel cytotoxic agent, inhibits proliferation in diffuse large B-cell lymphoma via the STAT3 pathway.
Xi Sun, Bo Li, Bingqian Xie, Zhijian Xu, Gaomei Chang, Shuaikang Chang, Liangning Hu, Weiliang Zhu

Cell Death Dis· October 2017

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The blueberry component pterostilbene has potent anti-myeloma activity in bortezomib-resistant cells.
Gege Chen, Zhijian Xu, Gaomei Chang, Jun Hou, Liangning Hu, Shuaikang Chang, Huiqun Wu, Weiliang Zhu

Oncol Rep· July 2017

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Dihydrocelastrol inhibits multiple myeloma cell proliferation and promotes apoptosis through ERK1/2 and IL-6/STAT3 pathways in vitro and in vivo.
Liangning Hu, Huiqun Wu, Bo Li, Dongliang Song, Guang Yang, Weiliang Zhu

Acta Biochim Biophys Sin (Shanghai)· May 2017

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TRIP13 impairs mitotic checkpoint surveillance and is associated with poor prognosis in multiple myeloma.
Yi Tao, Guang Yang, Hongxing Yang, Dongliang Song, Liangning Hu, Weiliang Zhu, Fenghuang Zhan

Oncotarget· April 2017

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