Publications by authors named "Libbey S O'Farrell"

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Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor.
Ajit Regmi, Eitaro Aihara, Michael E Christe, Gabor Varga, Thomas P Beyer, Xiaoping Ruan, Emily Beebe, Libbey S O'Farrell, Melissa A Bellinger, Aaron K Austin

Cell Metab· July 2024

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Tirzepatide did not impact metabolic adaptation in people with obesity, but increased fat oxidation.
Eric Ravussin, Guillermo Sanchez-Delgado, Corby K Martin, Robbie A Beyl, Frank L Greenway, Libbey S O'Farrell

Cell Metab· May 2025

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The pharmacological basis for nonpeptide agonism of the GLP-1 receptor by orforglipron.
Kyle W Sloop, Amy L Cox, David B Wainscott, Alex White, Brian A Droz, Libbey S O'Farrell

Sci Transl Med· December 2024

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Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor.
Ajit Regmi, Eitaro Aihara, Michael E Christe, Gabor Varga, Thomas P Beyer, Libbey S O'Farrell

Cell Metab· August 2024

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GIPR Agonism Enhances TZD-Induced Insulin Sensitivity in Obese IR Mice.
Ellen C Furber, Karissa Hyatt, Kyla Collins, Xinxin Yu, Brian A Droz, Libbey S O'Farrell

Diabetes· February 2024

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LY3437943, a novel triple glucagon, GIP, and GLP-1 receptor agonist for glycemic control and weight loss: From discovery to clinical proof of concept.
Tamer Coskun, Shweta Urva, William C Roell, Hongchang Qu, Corina Loghin, Libbey S O'Farrell

Cell Metab· September 2022

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GIPR agonism mediates weight-independent insulin sensitization by tirzepatide in obese mice.
Ricardo J Samms, Michael E Christe, Kyla Al Collins, Valentina Pirro, Brian A Droz, Libbey S O'Farrell

J Clin Invest· June 2021

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The anti-obesity effect of FGF19 does not require UCP1-dependent thermogenesis.
Patrick J Antonellis, Brian A Droz, Richard Cosgrove, Libbey S O'Farrell, Tamer Coskun

Mol Metab· December 2019

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Secretin-Activated Brown Fat Mediates Prandial Thermogenesis to Induce Satiation.
Yongguo Li, Katharina Schnabl, Sarah-Madeleine Gabler, Monja Willershäuser, Josefine Reber, Libbey S O'Farrell

Cell· November 2018

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Fibroblast growth factor 21 is not required for the antidiabetic actions of the thiazoladinediones.
Andrew C Adams, Tamer Coskun, Christine C Cheng, Libbey S O Farrell, Susan L Dubois

Mol Metab· September 2013

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Activation of prostaglandin E receptor 4 triggers secretion of gut hormone peptides GLP-1, GLP-2, and PYY.
Tamer Coskun, Libbey S O'Farrell, Samreen K Syed, Daniel A Briere, Lisa S Beavers

Endocrinology· January 2013

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Combination of a Beta adrenoceptor modulator and a norepinephrine-serotonin uptake inhibitor for the treatment of obesity.
Cynthia D Jesudason, James E Baker, Robert D Bryant, Jack W Fisher, Libbey S O'Farrell

ACS Med Chem Lett· August 2011

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