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Cell Metab July 2024 PMID 38878772

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor.

Ajit Regmi, Eitaro Aihara, Michael E Christe, Gabor Varga, Thomas P Beyer, Xiaoping Ruan, Emily Beebe, Libbey S O'Farrell, Melissa A Bellinger, Aaron K Austin, Yanzhu Lin, Haitao Hu, Debra L Konkol, Samantha Wojnicki, Adrienne K Holland

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Mentions

61
Peak: 43 in Jun 2024
across 2 sources since Jun 2024

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355,853
potential audience

Total likes

216

Video views

200

Mentions per month

Jun 2024 – Mar 2025

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AI synopsis

What people are saying

The discussions prominently feature constant references to the publication, suggesting a widespread acknowledgment of the research's importance. Phrases like 'trending' and 'new research' demonstrate an enthusiastic engagement with the findings, while users frequently highlight the implications for diabetes management, expressing sentiments about the drug's potential to change treatment paradigms.

AgreementModerate agreement

Most discussions show a positive reception towards the publication.

InterestHigh interest

The topic resonates well, indicating strong curiosity among the audience.

EngagementModerate engagement

Discussions are surface-level, mostly sharing links rather than in-depth analysis.

ImpactHigh impact

Participants view the research as having significant implications for diabetes treatment.

Abstract in brief

  • Tirzepatide, a new drug for type 2 diabetes, shows greater effectiveness in lowering glucose, body weight, and triglycerides compared to other treatments, but its cellular mechanisms are still being explored.
  • Research using human fat cells and mouse models reveals that GIPR agonism boosts insulin signaling and glucose uptake while increasing fat breakdown when insulin is low.
  • In obese mice, a long-acting GIPR agonist lowered triglyceride levels after eating and improved fat uptake in fat tissue, suggesting it helps manage fat storage and release differently depending on insulin levels.
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Cell Metabolism
@Cell_Metabolism · X

New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/a6eJ3etvvB https://t.co/hYIhdMxGLT

Jun 14, 2024 · 92 likes · 29 shares · 53,910 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Cell_Metabolism https://t.co/tetO1zrtc4

Jun 29, 2024 · 32 likes · 11 shares · 6,450 followers View post →
Cell Metabolism
@Cell_Metabolism · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/yTiUmZpVRM https://t.co/zrhsUFQigZ

Jul 5, 2024 · 23 likes · 7 shares · 53,910 followers View post →
Cell Metabolism
@Cell_Metabolism · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/JTd6mDbINm

Aug 9, 2024 · 20 likes · 2 shares · 53,910 followers View post →
Cell Metabolism
@Cell_Metabolism · X

New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/QV4YWGT4xC

Jun 29, 2024 · 16 likes · 2 shares · 53,910 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor #diabetes @Cell_Metabolism https://t.co/3EuQRk2Fdq

Jun 19, 2024 · 15 likes · 2 shares · 6,450 followers View post →

All mentions

Manoj Mayogi Mishra
@mayogisense · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Aug 10, 2024 · 2 shares · 573 followers View post →
Cell Metabolism
@Cell_Metabolism · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/JTd6mDbINm

Aug 9, 2024 · 20 likes · 2 shares · 53,910 followers View post →
PubMed Trending
@PubTrend · X

Trending on PubMed: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor. https://t.co/aPGvb6sg0r

Jul 11, 2024 · 5,166 followers View post →
the paper link
@the_paper_link · X

Trend top+1: Regmi A, ..., Roell W (Cell Metab) __Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor__ https://t.co/e3YhVyDGCq

Jul 7, 2024 · 138 followers View post →
CTEC - Zurich University Heart Center
@CTECresearch · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 6, 2024 · 7 shares · 808 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 5, 2024 · 7 shares · 32,514 followers View post →
Rubén Cereijo
@RubCereijo · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 5, 2024 · 7 shares · 322 followers View post →
Fábio Fonseca
@FbioFon84085623 · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 5, 2024 · 7 shares · 587 followers View post →
Bayar Jaff
@JaffBayar · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 5, 2024 · 7 shares · 606 followers View post →
Psicólogo Celestino González-Fernández ψ
@Tecnoestres · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 5, 2024 · 7 shares · 2,900 followers View post →
ⓧ ImTheRoute
@Imtheroute · X

RT @Cell_Metabolism: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP recept…

Jul 5, 2024 · 7 shares · 471 followers View post →
Cell Metabolism
@Cell_Metabolism · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/yTiUmZpVRM https://t.co/zrhsUFQigZ

Jul 5, 2024 · 23 likes · 7 shares · 53,910 followers View post →
Marcus Goncalves
@MarcusDGon · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor: Cell Metabolism https://t.co/ksrBqTIkqJ

Jul 2, 2024 · 3 likes · 2,553 followers View post →
the paper link
@the_paper_link · X

Trend top+9: Regmi A, ..., Roell W (Cell Metab) __Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor__ https://t.co/e3YhVyDGCq

Jul 1, 2024 · 138 followers View post →
choiLab
@jungminchoilab · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jul 1, 2024 · 11 shares · 336 followers View post →
CLQ Lab
@CLQLab · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jul 1, 2024 · 11 shares · 340 followers View post →
Bayar Jaff
@JaffBayar · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 30, 2024 · 11 shares · 606 followers View post →
Shams Salah Mahdi
@ShamsPath · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 30, 2024 · 11 shares · 1,467 followers View post →
System
@liyongcsco12 · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 30, 2024 · 11 shares · 64 followers View post →
Shugo Sasaki
@shugosasaki · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 30, 2024 · 2 shares · 238 followers View post →
Jaroslav Novotný
@novotnyjarosl · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 30, 2024 · 2 shares · 641 followers View post →
nike
@wot_mikey · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 30, 2024 · 11 shares · 476 followers View post →
tmtsq
@tmtsq121571 · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 29, 2024 · 11 shares · 51 followers View post →
Javierpa95
@javi95lol · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 29, 2024 · 11 shares · 99 followers View post →
Wilson (Yuqin Wu)
@Wilson79078233 · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 29, 2024 · 11 shares · 725 followers View post →
Brittany Moyce Gruber @bmgruber.bsky.social
@brittany_moyce · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Ce…

Jun 29, 2024 · 11 shares · 644 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor @Cell_Metabolism https://t.co/tetO1zrtc4

Jun 29, 2024 · 32 likes · 11 shares · 6,450 followers View post →
Cell Metabolism
@Cell_Metabolism · X

New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/QV4YWGT4xC

Jun 29, 2024 · 16 likes · 2 shares · 53,910 followers View post →
Om P. Dwivedi
@Om_P_Dwivedi · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor #di…

Jun 20, 2024 · 2 shares · 40 followers View post →
Ryan Marshall, PhD
@RNMarshallPhD · X

RT @Brunorm84: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor #di…

Jun 19, 2024 · 2 shares · 1,231 followers View post →
Bruno Ramos-Molina, PhD
@Brunorm84 · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor #diabetes @Cell_Metabolism https://t.co/3EuQRk2Fdq

Jun 19, 2024 · 15 likes · 2 shares · 6,450 followers View post →
Arshad Rashid
@arshadkema · X

Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor: Cell Metabolism https://t.co/7bVvuAIzic

Jun 16, 2024 · 3 likes · 1,016 followers View post →
Sharona Azriel
@SharonaAzriel · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 1,407 followers View post →
Dr Shraboni Ghosal, PhD
@ShraboniGhosal · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 1,929 followers View post →
iArmandoVBaneado
@iArmandoVBanned · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 69 followers View post →
rajivk-substack
@RajivkSubstack · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 20 followers View post →
Romana Stark
@Stark_BrainSci · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 60 followers View post →
Nithyanan Annamalai
@BlackSamrat · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 375 followers View post →
Eric
@ericsophia12 · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 16, 2024 · 29 shares · 94 followers View post →
Georgia
@GeorgiaColle · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 15, 2024 · 29 shares · 255 followers View post →
Paneni Lab
@PaneniLab · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 15, 2024 · 29 shares · 219 followers View post →
INTERNAL MEDICINE
@medicinterna · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 15, 2024 · 29 shares · 2,463 followers View post →
Jaroslav Novotný
@novotnyjarosl · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 15, 2024 · 29 shares · 641 followers View post →
Shams Salah Mahdi
@ShamsPath · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 15, 2024 · 29 shares · 1,467 followers View post →
Dr. Shashank Joshi
@AskDrShashank · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 32,514 followers View post →
Sigma Peptides
@SigmaPeptides · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 12 followers View post →
Manoj Mayogi Mishra
@mayogisense · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 573 followers View post →
The Phoenix Lab
@The_Phoenix_Lab · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 211 followers View post →
David Morales-Álamo
@D_Morales_Alamo · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 3,766 followers View post →
Javierpa95
@javi95lol · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 99 followers View post →
dec ⁽̨̡ ¨̮ ⁾̧̢ (slow)
@px_x_x · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 288 followers View post →
Sivaprakasam Chinnarasu, PhD
@sivabdubio · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 101 followers View post →
Moonii
@Moonii199009 · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 32 followers View post →
NP
@NerveKeeper · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 17,530 followers View post →
Dr. Chen Li
@ChenLi56084782 · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 225 followers View post →
Aaron Novikoff
@AaronNovikoff · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 432 followers View post →
Bayar Jaff
@JaffBayar · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 606 followers View post →
Philippe Froguel
@philippefroguel · X

RT @Cell_Metabolism: New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation…

Jun 14, 2024 · 29 shares · 5,024 followers View post →
Cell Metabolism
@Cell_Metabolism · X

New! Online now: Tirzepatide modulates the regulation of adipocyte nutrient metabolism through long-acting activation of the GIP receptor https://t.co/a6eJ3etvvB https://t.co/hYIhdMxGLT

Jun 14, 2024 · 92 likes · 29 shares · 53,910 followers View post →