Publications by authors named "Libor Macurek"

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MCL1 modulates mTORC1 signaling to promote bioenergetics and tumorigenesis.
Wentao Gui, Petr Paral, Bhavuk Dhamija, Eman Hagag, Martin Dusa, Libor Macurek

Nat Commun· December 2025

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Case-Control Study for 23 Cancer Types With Functional Analysis of : Risk Estimation and Clinical Recommendations in East Asia.
Yuri Takehara, Yoshiaki Usui, Lenka Stolařová, Petra Kleiblova, Yusuke Iwasaki, Libor Macurek

JCO Precis Oncol· September 2025

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In-frame germline TP53 variant impairs p53 oligomerization and predisposes to cancer.
Lucie Vanikova, Eva Machackova, Barbora Nemcova, Jana Soukupova, Silvia Petrezselyova, Libor Macurek

Sci Rep· August 2025

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An ATM-PPM1D Circuit Controls the Processing and Restart of DNA Replication Forks.
Yiting Cao, Yingzheng Wang, Jumana Badar, Matous Palek, Khoula Jaber, Libor Macurek

bioRxiv· May 2025

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Protein structure and interactions elucidated with in-cell NMR for different cell cycle phases and in 3D human tissue models.
Jan Rynes, Eva Istvankova, Michaela Dzurov Krafcikova, Enrico Luchinat, Letizia Barbieri, Libor Macurek

Commun Biol· February 2025

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PPM1D activity promotes cellular transformation by preventing senescence and cell death.
Miroslav Stoyanov, Andra S Martinikova, Katerina Matejkova, Klara Horackova, Petra Zemankova, Libor Macurek

Oncogene· October 2024

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A comprehensive study evaluating germline FANCG variants in predisposition to breast and ovarian cancer.
Jana Soukupova, Barbora Stastna, Madiha Kanwal, Jan Hojny, Petra Zemankova, Libor Macurek

Cancer Med· August 2024

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Hematopoietic stem cell fate under the influence of Ser/Thr protein phosphatases.
Meritxell Alberich-Jorda, Libor Macurek

Haematologica· July 2024

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RAD18 directs DNA double-strand break repair by homologous recombination to post-replicative chromatin.
Matous Palek, Natalie Palkova, , Petra Kleiblova, Zdenek Kleibl, Libor Macurek

Nucleic Acids Res· July 2024

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FAM110A promotes mitotic spindle formation by linking microtubules with actin cytoskeleton.
Cecilia Aquino-Perez, Mahira Safaralizade, Roman Podhajecky, Hong Wang, Zdenek Lansky, Libor Macurek

Proc Natl Acad Sci U S A· July 2024

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Many Ways to the Cell Cycle Exit after Inhibition of CDK4/6.
Libor Macůrek

Folia Biol (Praha)· April 2024

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PPM1D activity promotes the replication stress caused by cyclin E1 overexpression.
Andra S Martinikova, Miroslav Stoyanov, Anna Oravetzova, Yannick P Kok, Shibo Yu, Libor Macurek

Mol Oncol· January 2024

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Ppm1d truncating mutations promote the development of genotoxic stress-induced AML.
Monika Burocziova, Petr Danek, Anna Oravetzova, Zuzana Chalupova, Meritxell Alberich-Jorda, Libor Macurek

Leukemia· November 2023

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ENIGMA CHEK2gether Project: A Comprehensive Study Identifies Functionally Impaired CHEK2 Germline Missense Variants Associated with Increased Breast Cancer Risk.
Lenka Stolarova, Petra Kleiblova, Petra Zemankova, Barbora Stastna, Marketa Janatova, Libor Macurek

Clin Cancer Res· August 2023

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Importance of Germline and Somatic Alterations in Human , , and Genes Coding for MRN Complex.
Barbora Otahalova, Zuzana Volkova, Jana Soukupova, Petra Kleiblova, Marketa Janatova, Libor Macurek

Int J Mol Sci· March 2023

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Phosphorylation of TRF2 promotes its interaction with TIN2 and regulates DNA damage response at telomeres.
Radka Storchova, Matous Palek, Natalie Palkova, Pavel Veverka, Tomas Brom, Libor Macurek

Nucleic Acids Res· February 2023

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CDC25B is required for the metaphase I-metaphase II transition in mouse oocytes.
Ivana Ferencova, Michaela Vaskovicova, David Drutovic, Lucie Knoblochova, Libor Macurek

J Cell Sci· March 2022

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C53 Interacting with UFM1-Protein Ligase 1 Regulates Microtubule Nucleation in Response to ER Stress.
Anastasiya Klebanovych, Stanislav Vinopal, Eduarda Dráberová, Vladimíra Sládková, Tetyana Sulimenko

Cells· February 2022

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A novel assay for screening WIP1 phosphatase substrates in nuclear extracts.
Radka Storchova, Kamila Burdova, Matous Palek, René H Medema, Libor Macurek

FEBS J· October 2021

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CK1-mediated phosphorylation of FAM110A promotes its interaction with mitotic spindle and controls chromosomal alignment.
Cecilia Aquino Perez, Monika Burocziova, Gabriela Jenikova, Libor Macurek

EMBO Rep· July 2021

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Cyclin A2 localises in the cytoplasm at the S/G2 transition to activate PLK1.
Helena Silva Cascales, Kamila Burdova, Anna Middleton, Vladislav Kuzin, Erik Müllers, Libor Macurek

Life Sci Alliance· March 2021

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Germline Variants in Cancer Predisposition: Stalemate Rather than Checkmate.
Lenka Stolarova, Petra Kleiblova, Marketa Janatova, Jana Soukupova, Petra Zemankova, Libor Macurek

Cells· December 2020

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Identification of Germline Mutations in Melanoma Patients with Early Onset, Double Primary Tumors, or Family Cancer History by NGS Analysis of 217 Genes.
Lenka Stolarova, Sandra Jelinkova, Radka Storchova, Eva Machackova, Petra Zemankova, Libor Macurek

Biomedicines· October 2020

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Truncated PPM1D Prevents Apoptosis in the Murine Thymus and Promotes Ionizing Radiation-Induced Lymphoma.
Andra S Martinikova, Monika Burocziova, Miroslav Stoyanov, Libor Macurek

Cells· September 2020

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Phosphorylation of PLK3 Is Controlled by Protein Phosphatase 6.
Cecilia Aquino Perez, Matous Palek, Lenka Stolarova, Patrick von Morgen, Libor Macurek

Cells· June 2020

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