Publications by authors named "Linea N Toksvang"

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Role of common host genome variants in Childhood Acute Lymphoblastic Leukemia.
Theis Mikkelsen, Marianne Helenius, Mirella Ampatzidou, Andishe Attarbaschi, Liv Andres-Jensen, Linea Natalie Toksvang

Leukemia· December 2025

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LC-MS/MS quantification of 6-methylthio-2'-deoxyguanosine and 6-thio-2'-deoxyguanosine in genomic DNA with enzymatically synthesized isotope-labelled internal standards.
Malene Johanne Petersen, Allan Weimann, Maria Thastrup, Linea Natalie Toksvang, Kjeld Schmiegelow

Anal Bioanal Chem· November 2025

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Does allopurinol enhance efficacy of acute lymphoblastic leukemia maintenance therapy?
Kjeld Schmiegelow, Linea Natalie Toksvang, Valentino Conter

Haematologica· July 2025

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DNA-incorporated thioguanine to detect potential non-adherence to maintenance therapy in acute lymphoblastic leukemia.
Mathilde Rønne Koch, Anna Sofie Buhl Rasmussen, Bodil Als-Nielsen, Ximo Duarte, Gabriele Escherich, Linea Natalie Toksvang

Cancer Chemother Pharmacol· July 2025

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Therapeutic drug monitoring in acute lymphoblastic leukemia-a deep dive into pharmacokinetics, -dynamics, and -genetics of antileukemic drugs.
Linea N Toksvang, Leiah J Brigitha, Inge M van der Sluis, Erica Brivio, Raheel Raja

Expert Rev Clin Pharmacol· March 2025

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Pharmacokinetic-pharmacodynamic modeling of maintenance therapy for childhood acute lymphoblastic leukemia.
Anna Gebhard, Patrick Lilienthal, Markus Metzler, Manfred Rauh, Sebastian Sager, Linea Natalie Toksvang

Sci Rep· July 2023

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Maintenance therapy for acute lymphoblastic leukemia: basic science and clinical translations.
Linea N Toksvang, Shawn H R Lee, Jun J Yang, Kjeld Schmiegelow

Leukemia· July 2022

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Thiopurine Enhanced ALL Maintenance (TEAM): study protocol for a randomized study to evaluate the improvement in disease-free survival by adding very low dose 6-thioguanine to 6-mercaptopurine/methotrexate-based maintenance therapy in pediatric and adult patients (0-45 years) with newly diagnosed B-cell precursor or T-cell acute lymphoblastic leukemia treated according to the intermediate risk-high group of the ALLTogether1 protocol.
Linea Natalie Toksvang, Bodil Als-Nielsen, Christopher Bacon, Ruta Bertasiute, Ximo Duarte

BMC Cancer· May 2022

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DNA-TG and risk of sinusoidal obstruction syndrome in childhood acute lymphoblastic leukemia.
Linea Natalie Toksvang, Kathrine Grell, Stine Nygaard Nielsen, Jacob Nersting, Daniel Murdy

Leukemia· February 2022

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Prevalence of non-adherence and non-compliance during maintenance therapy in adults with acute lymphoblastic leukemia and their associations with survival.
Elsa Rán Kristjánsdóttir, Linea Natalie Toksvang, Kjeld Schmiegelow, Cecilie Utke Rank

Eur J Haematol· February 2022

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DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis.
Linea N Toksvang, Kathrine Grell, Jacob Nersting, Matilda Degn, Stine N Nielsen

Leukemia· January 2022

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Maintenance therapy and risk of osteonecrosis in children and young adults with acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study.
Linea Natalie Toksvang, Liv Andrés-Jensen, Cecilie Utke Rank, Riitta Niinimäki, Jacob Nersting

Cancer Chemother Pharmacol· November 2021

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No association between relapse hazard and thiopurine methyltransferase geno- or phenotypes in non-high risk acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study.
Stine Nygaard Nielsen, Linea Natalie Toksvang, Kathrine Grell, Jacob Nersting, Jonas Abrahamsson

Cancer Chemother Pharmacol· August 2021

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Hepatotoxicity during 6-thioguanine treatment in inflammatory bowel disease and childhood acute lymphoblastic leukaemia: A systematic review.
Linea Natalie Toksvang, Magnus Strøh Schmidt, Sofie Arup, Rikke Hebo Larsen, Thomas Leth Frandsen

PLoS One· January 2020

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Hepatic sinusoidal obstruction syndrome during maintenance therapy of childhood acute lymphoblastic leukemia is associated with continuous asparaginase therapy and mercaptopurine metabolites.
Linea Natalie Toksvang, Silvia De Pietri, Stine N Nielsen, Jacob Nersting, Birgitte K Albertsen

Pediatr Blood Cancer· September 2017

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Spontaneous blood pressure oscillations in mechanically ventilated patients with sepsis.
Ronan M G Berg, Ronni R Plovsing, Anders M Greve, Claus B Christiansen, Linea N Toksvang

Blood Press Monit· April 2016

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Symptoms of Central Anticholinergic Syndrome After Glycopyrrolate Administration in a 5-Year-Old Child.
Linea Natalie Toksvang, Ronni R Plovsing

A A Case Rep· January 2016

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Collaborative teaching strategies lead to retention of skills in acid-base physiology: a 2-yr follow-up study.
Jacob P Hartmann, Linea Natalie Toksvang, Ronan M G Berg

Adv Physiol Educ· June 2015

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Poor agreement between transcranial Doppler and near-infrared spectroscopy-based estimates of cerebral blood flow changes in sepsis.
Linea N Toksvang, Ronni R Plovsing, Marie W Petersen, Kirsten Møller, Ronan M G Berg

Clin Physiol Funct Imaging· September 2014

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Progressive intracranial hypertension and cerebral hypoperfusion in a fatal case of cerebral aspergilloma.
Linea Natalie Toksvang, Ronni R Plovsing, Ronan M G Berg

BMJ Case Rep· June 2014

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Collaborative strategies for teaching common acid-base disorders to medical students.
Marie Warrer Petersen, Linea Natalie Toksvang, Ronni R Plovsing, Ronan M G Berg

Adv Physiol Educ· March 2014

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Does the static cerebral autoregulatory plateau have a finite slope in healthy preterm neonates?
Linea Natalie Toksvang, Ronan M G Berg

Early Hum Dev· February 2014

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Using an essay competition as an alternative tool for enhancing the "learning from learners" teaching approach.
Ronan M G Berg, Linea Natalie Toksvang, Reza Jabbari

Adv Physiol Educ· September 2013

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Using a classic paper by Robin Fahraeus and Torsten Lindqvist to teach basic hemorheology.
Linea Natalie Toksvang, Ronan M G Berg

Adv Physiol Educ· June 2013

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