Publications by authors named "Linfei Hu"

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Enhancer-mediated NR2F2 recruitment activates BGN to promote tumor growth and shape tumor microenvironment in papillary thyroid cancer.
Mei Tao, Xianhui Ruan, Jialong Yu, Qiman Dong, Wei Luo, Linfei Hu, Jingzhu Zhao

Theranostics· December 2025

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Multi-omics analysis unveils dysregulation of the tumor immune microenvironment and development of a machine learning-based multi-gene classifier for predicting lateral lymph node metastasis in papillary thyroid carcinoma.
Qingxiang Yu, Weijing Hao, Yanbin He, Xianhui Ruan, Lin Liu, Jingzhu Zhao, Linfei Hu

Endocrine· October 2025

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Identification of stemness subtypes and prognostic modeling in thyroid cancer: the critical role of DPYSL3 in tumor progression and immune microenvironment.
Jialong Yu, Wei Luo, Guangwei Xu, Mei Tao, Yuqi Wang, Linfei Hu, Jingzhu Zhao, Xianhui Ruan

Discov Oncol· June 2025

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Persistent pre-exhausted CD8+ T cells shape the tumor immune microenvironment in anaplastic thyroid cancer.
Xianhui Ruan, Mei Tao, Yuanxing Dong, Linfei Hu, Guangwei Xu, Chuanxiang Hu, Yue Huang

Endocr Relat Cancer· March 2025

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Programmed cell death-related gene IL20RA facilitates tumor progression and remodels tumor microenvironment in thyroid cancer.
Yuqi Wang, Yunlong Zhang, Min Liu, Yu Liu, Yu Zeng, Shuping Wu, Linfei Hu, Xianhui Ruan, Jingzhu Zhao

Sci Rep· January 2025

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Multifocality increases the risk of central compartment lymph node metastasis but is not related to the risk of recurrence and death in papillary thyroid carcinoma.
Ying Gao, Mengran Tian, Xiukun Hou, Weijing Hao, Yanhui Zhang, Linfei Hu

Gland Surg· December 2024

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FATS inhibits the Wnt pathway and induces apoptosis through degradation of MYH9 and enhances sensitivity to paclitaxel in breast cancer.
Jin-Xuan Song, Yue Wang, Zhi-Peng Hua, Yue Huang, Lin-Fei Hu

Cell Death Dis· November 2024

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An Inducible CRISPR-dCas9-Based Transcriptional Repression System for Cancer Therapy.
Pengfei Gu, Jie Zhao, Wei Zhang, Xianhui Ruan, Linfei Hu

Small Methods· August 2024

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Targeted sequencing of DNA/RNA combined with radiomics predicts lymph node metastasis of papillary thyroid carcinoma.
Runjiao Zhang, Linfei Hu, Yanan Cheng, Luchen Chang, Li Dong

Cancer Imaging· June 2024

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Therapeutic targeting of TNIK in papillary thyroid carcinoma: a novel approach for tumor growth suppression.
Ruqian Zhang, Yongbo Yu, Yeran Yang, Meng Zhang, Xuan Zhang, Linfei Hu

Med Oncol· May 2024

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PARP inhibitor shuts down the global translation of thyroid cancer through promoting Pol II binding to DIMT1 pause.
Xiukun Hou, Mengran Tian, Junya Ning, Zhongyu Wang, Fengli Guo, Linfei Hu, Chuanxiang Hu, Jingzhu Zhao, Xianhui Ruan

Int J Biol Sci· August 2023

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Early Combined SHP2 Targeting Reverses the Therapeutic Resistance of Vemurafenib in Thyroid Cancer.
Weike Ma, Mengran Tian, Linfei Hu, Xianhui Ruan, Wei Zhang

J Cancer· May 2023

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An integrated nomogram combining deep learning, clinical characteristics and ultrasound features for predicting central lymph node metastasis in papillary thyroid cancer: A multicenter study.
Luchen Chang, Yanqiu Zhang, Jialin Zhu, Linfei Hu, Xiaoqing Wang

Front Endocrinol (Lausanne)· March 2023

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Targeting Aurora-A inhibits tumor progression and sensitizes thyroid carcinoma to Sorafenib by decreasing PFKFB3-mediated glycolysis.
Zhi Jingtai, Hu Linfei, Qian Yuyang, Kang Ning, Yun Xinwei, Ruan Xianhui, Huang Dongmei, Zhu Tianze

Cell Death Dis· March 2023

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Aurora kinase a promotes the progression of papillary thyroid carcinoma by activating the mTORC2-AKT signalling pathway.
Zewei Zhao, Huijuan Wang, Ning Kang, Zhongyu Wang, Xiukun Hou, Linfei Hu, Shuo Qie, Xianhui Ruan

Cell Biosci· December 2022

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To Explore the Inhibitory Mechanism of Quercetin in Thyroid Papillary Carcinoma through Network Pharmacology and Experiments.
Ying Sun, Wenjun Xie, Ning Kang, Jiaoyu Yi, Xianhui Ruan, Linfei Hu, Jingzhu Zhao

Dis Markers· December 2022

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Based on different immune responses under the glucose metabolizing type of papillary thyroid cancer and the response to anti-PD-1 therapy.
Wenjun Xie, Yu Zeng, Linfei Hu, Jiaru Hao, Yuzheng Chen, Huashui Li

Front Immunol· October 2022

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Surgery and Radioactive Iodine Therapeutic Strategy for Patients Greater Than 60 Years of Age with Differentiated Thyroid Cancer.
Tao Tang, Jingtai Zhi, Wei Zhang, Linfei Hu, Xianhui Ruan, Zhaohui Wang

J Healthc Eng· May 2022

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KDM1A promotes thyroid cancer progression and maintains stemness through the Wnt/β-catenin signaling pathway.
Wei Zhang, Xianhui Ruan, Yaoshuang Li, Jingtai Zhi, Linfei Hu

Theranostics· April 2022

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Pharmacological inhibition of Ref-1 enhances the therapeutic sensitivity of papillary thyroid carcinoma to vemurafenib.
Linfei Hu, Jun Zhang, Mengran Tian, Ning Kang, Guangwei Xu, Xianhui Ruan

Cell Death Dis· February 2022

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Reduced MHC class II expression in medullary thyroid cancer identifies patients with poor prognosis.
Xianhui Ruan, Jiaoyu Yi, Linfei Hu, Jingtai Zhi, Yu Zeng, Jianfeng Huang

Endocr Relat Cancer· January 2022

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Comprehensive analysis of PPPCs family reveals the clinical significance of PPP1CA and PPP4C in breast cancer.
Wenjun Xie, Ying Sun, Yu Zeng, Linfei Hu, Jingtai Zhi, Xianhui Ruan

Bioengineered· January 2022

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Targeting SHP2 sensitizes differentiated thyroid carcinoma to the MEK inhibitor.
Jingtai Zhi, Jiaoyu Yi, Xiukun Hou, Wei Wang, Weiwei Yang, Linfei Hu, Jianfeng Huang, Xianhui Ruan

Am J Cancer Res· January 2022

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Genome-wide identification of m6A-associated functional SNPs as potential functional variants for thyroid cancer.
Xianhui Ruan, Mengran Tian, Ning Kang, Weike Ma, Yu Zeng, Gaojian Zhuang, Linfei Hu

Am J Cancer Res· November 2021

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The mechanisms of celastrol in treating papillary thyroid carcinoma based on network pharmacology and experiment verification.
Jiaoyu Yi, Mengran Tian, Linfei Hu, Ning Kang, Weike Ma, Xianhui Ruan

Ann Transl Med· May 2021

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