Publications by authors named "Linglan Fang"

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Harnessing Deaminated DNA to Modulate mRNA Translation for Controlled and Sequential Protein Expression.
Jihun Choi, Tae Ung Jeong, Francis Cabanting, Juhyung Song, Cheoljun Park, Linglan Fang

Angew Chem Int Ed Engl· December 2025

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Localized 2'-OH Acylation at Poly(A) Extends RNA Translation.
Linglan Fang, Wenrui Zhong, Lu Xiao, Ryuta Shioi, Allan Lee

J Am Chem Soc· September 2025

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RNA infrastructure profiling illuminates transcriptome structure in crowded spaces.
Lu Xiao, Linglan Fang, Wenrui Zhong, Eric T Kool

Cell Chem Biol· December 2024

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Reversible RNA Acylation Using Bio-Orthogonal Chemistry Enables Temporal Control of CRISPR-Cas9 Nuclease Activity.
Bhoomika Pandit, Linglan Fang, Eric T Kool, Maksim Royzen

ACS Chem Biol· August 2024

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Profiling of drug resistance in Src kinase at scale uncovers a regulatory network coupling autoinhibition and catalytic domain dynamics.
Sujata Chakraborty, Ethan Ahler, Jessica J Simon, Linglan Fang, Zachary E Potter

Cell Chem Biol· February 2024

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2'-OH as a universal handle for studying intracellular RNAs.
Lu Xiao, Linglan Fang, Eric T Kool

Cell Chem Biol· January 2024

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Reactivity-based RNA profiling for analyzing transcriptome interactions of small molecules in human cells.
Linglan Fang, Eric T Kool

STAR Protoc· December 2023

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Efficient post-synthesis incorporation and conjugation of reactive ketones in RNA 2'-acylation.
Ryuta Shioi, Lu Xiao, Linglan Fang, Eric T Kool

Chem Commun (Camb)· December 2023

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Pervasive transcriptome interactions of protein-targeted drugs.
Linglan Fang, Willem A Velema, Yujeong Lee, Lu Xiao, Michael G Mohsen

Nat Chem· October 2023

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RNA Infrastructure Profiling Illuminates Transcriptome Structure in Crowded Spaces.
Lu Xiao, Linglan Fang, Eric T Kool

bioRxiv· October 2023

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Reversible 2'-OH acylation enhances RNA stability.
Linglan Fang, Lu Xiao, Yong Woong Jun, Yoshiyuki Onishi, Eric T Kool

Nat Chem· September 2023

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Diverse Reagent Scaffolds Provide Differential Selectivity of 2'-OH Acylation in RNA.
Lu Xiao, Linglan Fang, Sayantan Chatterjee, Eric T Kool

J Am Chem Soc· January 2023

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Acylation probing of "generic" RNA libraries reveals critical influence of loop constraints on reactivity.
Lu Xiao, Linglan Fang, Eric T Kool

Cell Chem Biol· August 2022

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The Right Tool for the Job: A Chemical and Genetic Toolkit for Interrogating DCLK1 Function.
Linglan Fang, Dustin J Maly

Cell Chem Biol· October 2020

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Parallel Chemoselective Profiling for Mapping Protein Structure.
Zachary E Potter, Ho-Tak Lau, Sujata Chakraborty, Linglan Fang, Miklos Guttman

Cell Chem Biol· August 2020

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How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture.
Linglan Fang, Jessica Vilas-Boas, Sujata Chakraborty, Zachary E Potter, Ames C Register

ACS Chem Biol· July 2020

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Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes.
Linglan Fang, Sujata Chakraborty, Emily M Dieter, Zachary E Potter, Chloe K Lombard

J Am Chem Soc· July 2019

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Targeting Dynamic ATP-Binding Site Features Allows Discrimination between Highly Homologous Protein Kinases.
Sujata Chakraborty, Takayuki Inukai, Linglan Fang, Martin Golkowski, Dustin J Maly

ACS Chem Biol· June 2019

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A Combined Approach Reveals a Regulatory Mechanism Coupling Src's Kinase Activity, Localization, and Phosphotransferase-Independent Functions.
Ethan Ahler, Ames C Register, Sujata Chakraborty, Linglan Fang, Emily M Dieter

Mol Cell· April 2019

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