Publications by authors named "Linhui Zhai"

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Systematic comparison of the effects of various fixatives on the stability of the cellular proteome.
Yulu Chen, Xun Zou, Lulu Wang, Yuan Gao, Hang Fu, Linhui Zhai

J Proteomics· January 2026

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In-depth analysis of data characteristics and comparative evaluation of dda and dia accuracy in label-free quantitative proteomics of biological samples.
Xun Zou, Lulu Wang, Yulu Chen, Hang Fu, Yuan Gao, Linhui Zhai

Clin Proteomics· December 2025

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Proteogenomic Characterization Reveals Metabolic Vulnerabilities and Aberrant Phosphorylation in Colorectal Metastasis to Liver.
Wensi Zhao, Lei Zhao, Yannan Lian, Zhiwei Liu, Yaqi Li, Linhui Zhai

Adv Sci (Weinh)· November 2025

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Editorial: Mechanism study of bioactive molecules using omics technology.
Linhui Zhai, Bingbing Hao, Eric B Dammer, Zhongwei Xu

Front Cell Dev Biol· November 2025

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Mass spectrometry-based characterization of histone post-translational modification.
Wensi Zhao, Jun Zhang, Kaifeng Chen, Jian Yuan, Linhui Zhai

Curr Opin Chem Biol· October 2025

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Visible-Light-Controlled Lysine-Selective Crosslinking Decodes Protein Complexes and Dynamic Interactomes in Live Cells.
Yali Xu, Hao Hu, Yu Ran, Wensi Zhao, An-Di Guo, Linhui Zhai

Angew Chem Int Ed Engl· August 2025

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Chemoproteomics reveals proteome-wide covalent and non-covalent targets of withaferin A.
Hui-Jun Nie, Ying-Jie Fu, Shang Long, Jia-Yu Wang, Wen-Si Zhao, Lin-Hui Zhai

Acta Pharmacol Sin· June 2025

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The Impact of Different Alkylation Quenching Methods on Tryptic Activity and Protein Identification in Proteomics Sample Preparation.
Yuan Gao, Min Wang, Lulu Wang, Xinglong Jia, Chunqiu Hu, Linhui Zhai

J Mass Spectrom· June 2025

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Integrative proteogenomic and pharmacological landscape of acute myeloid leukaemia.
Hanlin Wang, Jun-Yu Xu, Tao Wang, Gaoya Xu, Guanghao Luo, Linhui Zhai

Sci Bull (Beijing)· April 2025

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Comprehensive Optimization of Packing Parameters for Hydraulic-Packed Capillary Columns.
Chunqiu Hu, Hang Fu, Lulu Wang, Yuan Gao, Ruidong Li, Linhui Zhai

Rapid Commun Mass Spectrom· April 2025

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Comprehensive multi-omics analysis elucidates colchicine-induced toxicity mechanisms and unveils the therapeutic potential of MLN4924 and kinase inhibitors.
Lin-Hui Zhai, Xing-Long Jia, Yu-Lu Chen, Mu-Yin Liu, Jing-Dan Zhang

Acta Pharmacol Sin· March 2025

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E3 ligase FBXW7 suppresses brown fat expansion and browning of white fat.
Jian Yu, Xuejiang Gu, Yingying Guo, Mingyuan Gao, Shimiao Cheng, Linhui Zhai

EMBO Rep· February 2025

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SHP2-Triggered Endothelial Cell Activation Fuels Estradiol-Independent Endometrial Sterile Inflammation.
Jie Pan, Jiao Qu, Wen Fang, Lixin Zhao, Wei Zheng, Linhui Zhai

Adv Sci (Weinh)· November 2024

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Publisher Correction: Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers.
Baijun Dong, Jun-Yu Xu, Yuqi Huang, Jiacheng Guo, Qun Dong, Linhui Zhai

Nat Cancer· November 2024

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Integrative proteogenomic profiling of high-risk prostate cancer samples from Chinese patients indicates metabolic vulnerabilities and diagnostic biomarkers.
Baijun Dong, Jun-Yu Xu, Yuqi Huang, Jiacheng Guo, Qun Dong, Linhui Zhai

Nat Cancer· September 2024

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P4HA2 hydroxylates SUFU to regulate the paracrine Hedgehog signaling and promote B-cell lymphoma progression.
Quanfu Li, Yiyang Liu, Jingxian Wu, Zewen Zhu, Jianjun Fan, Linhui Zhai

Leukemia· August 2024

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Proteomics analysis of histone deacetylase inhibitor-resistant solid tumors reveals resistant signatures and potential drug combinations.
Bing-Bing Hao, Ke Ma, Jun-Yu Xu, Ru-Feng Fan, Wen-Si Zhao, Lin-Hui Zhai

Acta Pharmacol Sin· June 2024

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The application of proteomics and phosphoproteomics to reveal the molecular mechanism of salidroside in ameliorating myocardial hypoxia.
Zhongwei Xu, Kaiyuan Fan, Heng Li, Lulu Wang, Wenqing Zhu, Linhui Zhai

Heliyon· May 2024

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DDX5 inhibits hyaline cartilage fibrosis and degradation in osteoarthritis via alternative splicing and G-quadruplex unwinding.
Qianqian Liu, Mingrui Han, Zhigui Wu, Wenqiang Fu, Jun Ji, Linhui Zhai

Nat Aging· May 2024

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Substrate and Functional Diversity of Protein Lysine Post-translational Modifications.
Bingbing Hao, Kaifeng Chen, Linhui Zhai, Muyin Liu, Bin Liu

Genomics Proteomics Bioinformatics· May 2024

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Spatiotemporal and direct capturing global substrates of lysine-modifying enzymes in living cells.
Hao Hu, Wei Hu, An-Di Guo, Linhui Zhai, Song Ma

Nat Commun· February 2024

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Metabolic regulation of homologous recombination repair by MRE11 lactylation.
Yuping Chen, Jinhuan Wu, Linhui Zhai, Tingting Zhang, Hui Yin

Cell· January 2024

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Integrative Proteomic Analysis Reveals the Cytoskeleton Regulation and Mitophagy Difference Between Ischemic Cardiomyopathy and Dilated Cardiomyopathy.
Muyin Liu, Linhui Zhai, Zhaohua Yang, Su Li, Tianxian Liu

Mol Cell Proteomics· December 2023

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In-depth urinary and exosome proteome profiling analysis identifies novel biomarkers for diabetic kidney disease.
Shichun Du, Linhui Zhai, Shu Ye, Le Wang, Muyin Liu

Sci China Life Sci· November 2023

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Spatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors.
An-Di Guo, Ke-Nian Yan, Hao Hu, Linhui Zhai, Teng-Fei Hu

Nat Chem· June 2023

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