Publications by authors named "Linlei Chen"

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Risk assessment of 2024 cattle H5N1 using age-stratified serosurveillance data.
Lin-Lei Chen, Xiaojuan Zhang, Kang Zhang, Brian Pui-Chun Chan, Jacqueline Kwan Yuk Yuen, Honglin Chen

Emerg Microbes Infect· December 2025

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E
Enhanced replication of a contemporary avian influenza A H9N2 virus in human respiratory organoids.
Lin-Lei Chen, Jonathan Daniel Ip, Wan-Mui Chan, Stephanie Joy-Ann Lam, Rhoda Cheuk-Ying Leung, Honglin Chen

Emerg Microbes Infect· December 2025

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Pathogenicity, virological features, and immune evasion of SARS-CoV-2 JN.1-derived variants including JN.1.7, KP.2, KP.3, and KP.3.1.1.
Jialu Shi, Xiaoyu Zhao, Xiaohui Jin, Jiayan Li, Yuanchen Liu, Zhe Chen, Lin-Lei Chen

Nat Commun· December 2025

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Avian influenza virus A(H5N1) genotype D1.1 is better adapted to human nasal and airway organoids than genotype B3.13.
Xiaojuan Zhang, Stephanie Joy-Ann Lam, Lin-Lei Chen, Carol Ho-Yan Fong, Wan-Mui Chan, Honglin Chen

J Infect Dis· November 2025

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A
A branched peptide targets virus and host to block influenza virus and rhinovirus entry.
Xinjie Meng, Chuyuan Zhang, Xiankun Wang, Jilong Shi, Zixian Song, Yao Chen, Linlei Chen

Antimicrob Agents Chemother· August 2025

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Lineage-specific pathogenicity, immune evasion, and virological features of SARS-CoV-2 BA.2.86/JN.1 and EG.5.1/HK.3.
Yuanchen Liu, Xiaoyu Zhao, Jialu Shi, Yajie Wang, Huan Liu, Lin-Lei Chen

Nat Commun· October 2024

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Global emergence of neuraminidase inhibitor-resistant influenza A(H1N1)pdm09 viruses with I223V and S247N mutations: implications for antiviral resistance monitoring.
Rhoda Cheuk-Ying Leung, Jonathan Daniel Ip, Lin-Lei Chen, Wan-Mui Chan, Kelvin Kai-Wang To

Lancet Microbe· July 2024

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C
Characterizing fitness and immune escape of SARS-CoV-2 EG.5 sublineage using elderly serum and nasal organoid.
Xiaojuan Zhang, Stephanie Joy-Ann Lam, Jonathan Daniel Ip, Carol Ho-Yan Fong, Allen Wing-Ho Chu, Lin-Lei Chen, Vincent Chi-Chung Cheng

iScience· May 2024

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Humoral and cellular immunity against different SARS-CoV-2 variants in patients with chronic kidney disease.
Desmond Yat-Hin Yap, Carol Ho-Yan Fong, Xiaojuan Zhang, Jonathan Daniel Ip, Wan-Mui Chan, Lin-Lei Chen, Vincent Chi-Chung Cheng

Sci Rep· November 2023

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D
Determination of seroprevalence and kinetics of humoral response using mpox virus A29 protein.
Jian-Piao Cai, Wing-Ming Chu, Anthony Raymond Tam, Kun Wang, Yuting Han, Lin-Lei Chen, Vincent Chi-Chung Cheng, Zhiwei Chen

Commun Med (Lond)· November 2023

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T
The viral fitness and intrinsic pathogenicity of dominant SARS-CoV-2 Omicron sublineages BA.1, BA.2, and BA.5.
Huiping Shuai, Jasper Fuk-Woo Chan, Bingjie Hu, Yue Chai, Chaemin Yoon, Yuanchen Liu, Lin-Lei Chen

EBioMedicine· September 2023

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Rational design of a booster vaccine against COVID-19 based on antigenic distance.
Ye-Fan Hu, Terrence Tsz-Tai Yuen, Hua-Rui Gong, Bingjie Hu, Jing-Chu Hu, Lin-Lei Chen

Cell Host Microbe· August 2023

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B
Broad-spectrum humanized monoclonal neutralizing antibody against SARS-CoV-2 variants, including the Omicron variant.
Kun Wen, Jian-Piao Cai, Xiaodi Fan, Xiaojuan Zhang, Cuiting Luo, Lin-Lei Chen

Front Cell Infect Microbiol· August 2023

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Omicron sublineage recombinant XBB evades neutralising antibodies in recipients of BNT162b2 or CoronaVac vaccines.
Xiaojuan Zhang, Lin-Lei Chen, Jonathan Daniel Ip, Wan-Mui Chan, Ivan Fan-Ngai Hung

Lancet Microbe· March 2023

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I
Intranasal Boosting with Spike Fc-RBD of Wild-Type SARS-CoV-2 Induces Neutralizing Antibodies against Omicron Subvariants and Reduces Viral Load in the Nasal Turbinate of Mice.
Jian-Piao Cai, Cuiting Luo, Kun Wang, Hehe Cao, Lin-Lei Chen, Honglin Chen, Zhiwei Chen

Viruses· March 2023

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E
Effect of vaccine booster, vaccine type, and hybrid immunity on humoral and cellular immunity against SARS-CoV-2 ancestral strain and Omicron variant sublineages BA.2 and BA.5 among older adults with comorbidities: a cross sectional study.
Carol Ho-Yan Fong, Xiaojuan Zhang, Lin-Lei Chen, Rosana Wing-Shan Poon, Brian Pui-Chun Chan

EBioMedicine· February 2023

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Omicron variant susceptibility to neutralizing antibodies induced in children by natural SARS-CoV-2 infection or COVID-19 vaccine.
Lin-Lei Chen, Gilbert T Chua, Lu Lu, Brian Pui-Chun Chan, Joshua Sung-Chih Wong

Emerg Microbes Infect· December 2022

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SARS-CoV-2 IgG seropositivity after the severe Omicron wave of COVID-19 in Hong Kong.
Rosana Wing-Shan Poon, Brian Pui-Chun Chan, Wan-Mui Chan, Carol Ho-Yan Fong, Xiaojuan Zhang, Lin-Lei Chen, Vincent Chi-Chung Cheng

Emerg Microbes Infect· December 2022

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S
Serum neutralisation of the SARS-CoV-2 omicron sublineage BA.2.
Lin-Lei Chen, Allen Wing-Ho Chu, Ricky Rui-Qi Zhang, Ivan Fan-Ngai Hung, Kelvin Kai-Wang To

Lancet Microbe· June 2022

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Contribution of low population immunity to the severe Omicron BA.2 outbreak in Hong Kong.
Lin-Lei Chen, Syed Muhammad Umer Abdullah, Wan-Mui Chan, Brian Pui-Chun Chan, Jonathan Daniel Ip, Vincent Chi-Chung Cheng

Nat Commun· June 2022

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Boosting of serum neutralizing activity against the Omicron variant among recovered COVID-19 patients by BNT162b2 and CoronaVac vaccines.
Lu Lu, Lin-Lei Chen, Ricky Rui-Qi Zhang, Owen Tak-Yin Tsang, Jacky Man-Chun Chan

EBioMedicine· May 2022

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Interferon-gamma inhibits influenza A virus cellular attachment by reducing sialic acid cluster size.
Carol Ho-Yan Fong, Lu Lu, Lin-Lei Chen, Man-Lung Yeung, Anna Jinxia Zhang

iScience· April 2022

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Antibody Response of Combination of BNT162b2 and CoronaVac Platforms of COVID-19 Vaccines against Omicron Variant.
Ka-Wa Khong, Danlei Liu, Ka-Yi Leung, Lu Lu, Hoi-Yan Lam, Linlei Chen, Honglin Chen

Vaccines (Basel)· January 2022

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Antibody Response of BNT162b2 and CoronaVac Platforms in Recovered Individuals Previously Infected by COVID-19 against SARS-CoV-2 Wild Type and Delta Variant.
Ruiqi Zhang, Ka-Wa Khong, Ka-Yi Leung, Danlei Liu, Yujing Fan, Linlei Chen, Honglin Chen

Vaccines (Basel)· December 2021

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