Publications by authors named "Linna An"

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Modeling protein-small molecule conformational ensembles with PLACER.
Ivan Anishchenko, Yakov Kipnis, Indrek Kalvet, Guangfeng Zhou, Rohith Krishna, Anna Lauko, Linna An, Frank DiMaio

Proc Natl Acad Sci U S A· November 2025

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Modeling protein-small molecule conformational ensembles with PLACER.
Ivan Anishchenko, Yakov Kipnis, Indrek Kalvet, Guangfeng Zhou, Rohith Krishna, Anna Lauko, Linna An, Frank DiMaio

bioRxiv· September 2025

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Design of Orthogonal Far-Red, Orange and Green Fluorophore-binding Proteins for Multiplex Imaging.
Long Tran, Shajesh Sharma, Steffen Klein, David Juergens, Justin Decarreau, Yujia Wang, Alex Kang, Linna An

bioRxiv· September 2025

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Integrated biotechnological and AI innovations for crop improvement.
Guotian Li, Linna An, Wanneng Yang, Lei Yang, Tong Wei, Jianglin Wang, John H Doonan, Evans S Lagudah

Nature· July 2025

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Comparative effectiveness of monotherapy vs. combination therapy for postoperative central nervous system infections in neurosurgical patients: a retrospective cohort study.
Muyun Li, Wei Meng, Linna An, Xiaoqi Lin, Shangjie Yang, Qiang Fu, Jie Wang, Jianhua Wang, Yubo Wang

BMC Infect Dis· May 2025

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Atomic context-conditioned protein sequence design using LigandMPNN.
Justas Dauparas, Gyu Rie Lee, Robert Pecoraro, Linna An, Ivan Anishchenko

Nat Methods· April 2025

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Binding and sensing diverse small molecules using shape-complementary pseudocycles.
Linna An, Meerit Said, Long Tran, Sagardip Majumder, Inna Goreshnik, Ivan Anishchenko, Brian Coventry, Alex Kang, David Feldman, Mariana Garcia Sanchez, Anastassia A Vorobieva

Science· July 2024

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De novo design of diverse small molecule binders and sensors using Shape Complementary Pseudocycles.
Linna An, Meerit Said, Long Tran, Sagardip Majumder, Inna Goreshnik, Ivan Anishchenko, Brian Coventry, Alex Kang, David Feldman, Mariana Garcia Sanchez, Anastassia A Vorobieva

bioRxiv· December 2023

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Hallucination of closed repeat proteins containing central pockets.
Linna An, Derrick R Hicks, Dmitri Zorine, Justas Dauparas, Basile I M Wicky, Hannah Nguyen, Alex Kang

Nat Struct Mol Biol· November 2023

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De Novo Protein Design Using the Blueprint Builder in Rosetta.
Linna An, Gyu Rie Lee

Curr Protoc Protein Sci· December 2020

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-Methyltransferase-Mediated Incorporation of a β-Amino Acid in Lanthipeptides.
Jeella Z Acedo, Ian R Bothwell, Linna An, Abby Trouth, Clara Frazier, Wilfred A van der Donk

J Am Chem Soc· October 2019

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Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
Linna An, Dillon P Cogan, Claudio D Navo, Gonzalo Jiménez-Osés, Satish K Nair, Wilfred A van der Donk

Nat Chem Biol· October 2018

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Enzyme-Controlled Intracellular Self-Assembly of (18)F Nanoparticles for Enhanced MicroPET Imaging of Tumor.
Yaling Liu, Qingqing Miao, Pei Zou, Longfei Liu, Xiaojing Wang, Linna An, Xiaoliu Zhang, Xiangping Qian, Gaolin Liang

Theranostics· April 2016

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Intracellular Self-Assembly of Taxol Nanoparticles for Overcoming Multidrug Resistance.
Yue Yuan, Lin Wang, Wei Du, Zhanling Ding, Jia Zhang, Tao Han, Linna An, Huafeng Zhang, Gaolin Liang

Angew Chem Int Ed Engl· August 2015

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Intracellular Disassembly of Self-Quenched Nanoparticles Turns NIR Fluorescence on for Sensing Furin Activity in Cells and in Tumors.
Yue Yuan, Jia Zhang, Qinjingwen Cao, Linna An, Gaolin Liang

Anal Chem· June 2015

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Intracellular Self-Assembly and Disassembly of (19)F Nanoparticles Confer Respective "Off" and "On" (19)F NMR/MRI Signals for Legumain Activity Detection in Zebrafish.
Yue Yuan, Shuchao Ge, Hongbin Sun, Xuejiao Dong, Hongxin Zhao, Linna An, Jia Zhang, Junfeng Wang, Gaolin Liang

ACS Nano· May 2015

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Peptide-based nanostructures for cancer diagnosis and therapy.
Linna An, M Rehan H Shah Gilani, Gaolin Liang

Curr Med Chem· February 2015

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Controlled intracellular self-assembly and disassembly of 19F nanoparticles for MR imaging of caspase 3/7 in zebrafish.
Yue Yuan, Hongbin Sun, Shuchao Ge, Mengjing Wang, Hongxin Zhao, Lin Wang, Linna An, Jia Zhang, Huafeng Zhang, Junfeng Wang, Gaolin Liang

ACS Nano· January 2015

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Multifunctional electroactive heteroatom-doped carbon aerogels.
Bo You, Peiqun Yin, Linna An

Small· November 2014

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Oligomeric nanoparticles functionalized with NIR-emitting CdTe/CdS QDs and folate for tumor-targeted imaging.
Yue Yuan, Jia Zhang, Linna An, Qinjingwen Cao, Yun Deng, Gaolin Liang

Biomaterials· September 2014

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Fluorescent switch for fast and selective detection of mercury (II) ions in vitro and in living cells and a simple device for its removal.
Yue Yuan, Shenlong Jiang, Qingqing Miao, Jia Zhang, Mengjing Wang, Linna An, Yafeng Guan, Qun Zhang, Gaolin Liang

Talanta· July 2014

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Using magnetic resonance imaging to study enzymatic hydrogelation.
Weijuan Wang, Junchao Qian, Anming Tang, Linna An, Kai Zhong, Gaolin Liang

Anal Chem· June 2014

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Labeling thiols on proteins, living cells, and tissues with enhanced emission induced by FRET.
Yue Yuan, Xijun Wang, Bin Mei, Dongxin Zhang, Anming Tang, Linna An, Jun Jiang, Gaolin Liang

Sci Rep· December 2013

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