Publications by authors named "Linu John"

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Analog of prolactin-releasing peptide reduces body weight primarily through sustained fatty acid oxidation rather than hypophagia.
Claire H Feetham, Sam Groom, Linu M John, Berit Ostergaard Christoffersen, Valeria Collabolletta

Cell Metab· December 2025

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Correction to "NN1213 - A Potent, Long-Acting, and Selective Analog of Human Amylin".
Kirsten Dahl, Kirsten Raun, Jakob Lerche Hansen, Christian Poulsen, Charlotta D de la Cour, Linu M John

J Med Chem· December 2024

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Housing mice near vs. below thermoneutrality affects drug-induced weight loss but does not improve prediction of efficacy in humans.
Julie M Jacobsen, Natalia Petersen, Lola Torz, Marina K Gerstenberg, Kent Pedersen, Linu M John

Cell Rep· August 2024

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NN1213 - A Potent, Long-Acting, and Selective Analog of Human Amylin.
Kirsten Dahl, Kirsten Raun, Jakob Lerche Hansen, Christian Poulsen, Charlotta D de la Cour, Linu M John

J Med Chem· July 2024

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Body weight lowering effect of glucose-dependent insulinotropic polypeptide and glucagon-like peptide receptor agonists is more efficient in RAMP1/3 KO than in WT mice.
Andrea S Leuthardt, Christina N Boyle, Kirsten Raun, Thomas A Lutz, Linu M John

Eur J Pharmacol· September 2023

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Housing-temperature reveals energy intake counter-balances energy expenditure in normal-weight, but not diet-induced obese, male mice.
Linu Mary John, Natalia Petersen, Marina Kjærgaard Gerstenberg, Lola Torz, Kent Pedersen

Commun Biol· September 2022

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Beyond appetite regulation: Targeting energy expenditure, fat oxidation, and lean mass preservation for sustainable weight loss.
Berit Østergaard Christoffersen, Guillermo Sanchez-Delgado, Linu Mary John, Donna H Ryan, Kirsten Raun

Obesity (Silver Spring)· April 2022

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NPFF Decreases Activity of Human Arcuate NPY Neurons: A Study in Embryonic-Stem-Cell-Derived Model.
Lola Torz, Kristoffer Niss, Sofia Lundh, Jens C Rekling, Carlos Damian Quintana, Linu Mary John

Int J Mol Sci· March 2022

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prediction of pseudo-allergenic response via MRGPRX2.
Linu M John, Charlotte M Dalsgaard, Claus B Jeppesen, Kilian W Conde-Frieboes, Katrine Baumann

J Immunotoxicol· December 2021

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A selective role for receptor activity-modifying proteins in subchronic action of the amylin selective receptor agonist NN1213 compared with salmon calcitonin on body weight and food intake in male mice.
Soraya Arrigoni, Christelle Le Foll, Andrea Cabak, Sofia Lundh, Kirsten Raun, Linu M John

Eur J Neurosci· August 2021

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Central control of energy balance by amylin and calcitonin receptor agonists and their potential for treatment of metabolic diseases.
Hannah Louise Zakariassen, Linu Mary John, Thomas Alexander Lutz

Basic Clin Pharmacol Toxicol· September 2020

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FGF21 regulates hepatic metabolic pathways to improve steatosis and inflammation.
Helle Keinicke, Gao Sun, Caroline M Junker Mentzel, Merete Fredholm, Linu Mary John

Endocr Connect· August 2020

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Salmon calcitonin distributes into the arcuate nucleus to a subset of NPY neurons in mice.
Hannah Louise Zakariassen, Linu Mary John, Jens Lykkesfeldt, Kirsten Raun, Tine Glendorf

Neuropharmacology· May 2020

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Semaglutide lowers body weight in rodents via distributed neural pathways.
Sanaz Gabery, Casper G Salinas, Sarah J Paulsen, Jonas Ahnfelt-Rønne, Tomas Alanentalo, Linu M John

JCI Insight· March 2020

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Quantitative whole-brain 3D imaging of tyrosine hydroxylase-labeled neuron architecture in the mouse MPTP model of Parkinson's disease.
Urmas Roostalu, Casper B G Salinas, Ditte D Thorbek, Jacob L Skytte, Katrine Fabricius, Linu M John

Dis Model Mech· November 2019

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GFRAL is the receptor for GDF15 and is required for the anti-obesity effects of the ligand.
Linda Yang, Chih-Chuan Chang, Zhe Sun, Dennis Madsen, Haisun Zhu, Linu Mary John

Nat Med· October 2017

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Nontranscriptional modulation of intracellular Ca2+ signaling by ligand stimulated thyroid hormone receptor.
Nuttawut Saelim, Linu M John, Jun Wu, Jeong Soon Park, Yidong Bai

J Cell Biol· December 2004

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Fibroblast growth factor 19 increases metabolic rate and reverses dietary and leptin-deficient diabetes.
Ling Fu, Linu M John, Sean H Adams, Xing Xian Yu, Elizabeth Tomlinson

Endocrinology· June 2004

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Transgenic mice expressing human fibroblast growth factor-19 display increased metabolic rate and decreased adiposity.
Elizabeth Tomlinson, Ling Fu, Linu John, Bruce Hultgren, Xiaojian Huang

Endocrinology· May 2002

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