Publications by authors named "Lionel Pochet"

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assessment of the risk of ABCB1-mediated drug-drug interaction between rivaroxaban and tacrolimus in human embryonic kidney 293 recombinant cell lines.
Gwenaëlle Mahieu, Anne-Laure Sennesael, Lionel Pochet, Vincent Haufroid, Françoise Van Bambeke

Res Pract Thromb Haemost· July 2024

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Coumarins as factor XIIa inhibitors: Potency and selectivity improvements using a fragment-based strategy.
Clara Davoine, Amandine Traina, Jonathan Evrard, Steve Lanners, Marianne Fillet, Lionel Pochet

Eur J Med Chem· November 2023

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Fragment Hit Discovery and Binding Site Characterization by Indirect Affinity Capillary Electrophoresis: Application to Factor XIIa.
Clara Davoine, Alissia Pardo, Lionel Pochet, Marianne Fillet

Anal Chem· November 2021

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Key amino acid residues in homoserine-acetyltransferase from M. tuberculosis give insight into the evolution of MetX family of enzymes - HAT, SAT and HST.
Bhavna Maurya, Melwin Colaço, Johan Wouters, Lionel Pochet, Sandra Misquith

Biochimie· October 2021

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Factor XII/XIIa inhibitors: Their discovery, development, and potential indications.
Clara Davoine, Charlotte Bouckaert, Marianne Fillet, Lionel Pochet

Eur J Med Chem· December 2020

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MetA (Rv3341) from Mycobacterium tuberculosis H37Rv strain exhibits substrate dependent dual role of transferase and hydrolase activity.
Bhavna Maurya, Lionel Pochet, Johan Wouters, Melwin Colaço, Sandra Misquith

Biochimie· December 2020

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Assessment of low plasma concentrations of apixaban in the periprocedural setting.
Sarah Lessire, Anne-Sophie Dincq, Romain Siriez, Lionel Pochet, Anne-Laure Sennesael

Int J Lab Hematol· August 2020

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Pharmacomodulations of the benzoyl-thiosemicarbazide scaffold reveal antimicrobial agents targeting d-alanyl-d-alanine ligase in bacterio.
Alice Ameryckx, Lionel Pochet, Gang Wang, Esra Yildiz, Bouazza Es Saadi

Eur J Med Chem· August 2020

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Development of new methodologies for the chromogenic estimation of betrixaban concentrations in plasma.
Romain Siriez, Jonathan Evrard, Jean-Michel Dogné, Lionel Pochet, Céline Bouvy

Int J Lab Hematol· April 2019

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Development and validation of a liquid chromatography/tandem mass spectrometry method for the simultaneous quantification of serotonin and thromboxane B2 from activated platelets.
Valentine Minet, Jonathan Evrard, Christelle Vancraeynest, Jean-Michel Dogné, François Mullier, Lionel Pochet

Int J Lab Hematol· December 2018

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1-(2-Hydroxybenzoyl)-thiosemicarbazides are promising antimicrobial agents targeting d-alanine-d-alanine ligase in bacterio.
Alice Ameryckx, Léopold Thabault, Lionel Pochet, Serge Leimanis, Jacques H Poupaert

Eur J Med Chem· November 2018

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Betrixaban: Impact on Routine and Specific Coagulation Assays-A Practical Laboratory Guide.
Romain Siriez, Jonathan Evrard, Jean-Michel Dogné, Lionel Pochet, Damien Gheldof

Thromb Haemost· July 2018

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Effect of ABCB1 genetic polymorphisms on the transport of rivaroxaban in HEK293 recombinant cell lines.
Anne-Laure Sennesael, Nadtha Panin, Christelle Vancraeynest, Lionel Pochet, Anne Spinewine

Sci Rep· July 2018

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Enhancing Action of Positive Allosteric Modulators through the Design of Dimeric Compounds.
Thomas Drapier, Pierre Geubelle, Charlotte Bouckaert, Lise Nielsen, Saara Laulumaa, Lionel Pochet

J Med Chem· June 2018

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Estimation of Rivaroxaban Plasma Concentrations in the Perioperative Setting in Patients With or Without Heparin Bridging.
Sarah Lessire, Jonathan Douxfils, Lionel Pochet, Anne-Sophie Dincq, Anne-Sophie Larock

Clin Appl Thromb Hemost· January 2018

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31ièmes Journées Franco-Belges de Pharmacochimie: Meeting Report.
Raphaël Frédérick, Lionel Pochet, Pascal De Tullio, François Dufrasne

Pharmaceuticals (Basel)· December 2017

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Capillary electrophoresis in the context of drug discovery.
Elena Farcaş, Lionel Pochet, Jacques Crommen, Anne-Catherine Servais, Marianne Fillet

J Pharm Biomed Anal· September 2017

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An optimized dRVVT-based assay to estimate the intensity of anticoagulation in patients treated with direct oral anticoagulants.
Anne-Laure Sennesael, Thomas Exner, Bernard Chatelain, Sarah Lessire, Anne-Sophie Larock, Lionel Pochet

Thromb Res· September 2017

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Discovery and assessment of water soluble coumarins as inhibitors of the coagulation contact pathway.
Charlotte Bouckaert, Shu Zhu, José W P Govers-Riemslag, Maxime Depoorter, Scott L Diamond, Lionel Pochet

Thromb Res· September 2017

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Synthesis, evaluation and structure-activity relationship of new 3-carboxamide coumarins as FXIIa inhibitors.
Charlotte Bouckaert, Silvia Serra, Grégoire Rondelet, Eduard Dolušić, Johan Wouters, Lionel Pochet

Eur J Med Chem· March 2016

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Fully automated electrophoretically mediated microanalysis for CYP1A1 activity monitoring optimized by multivariate approach.
Elena Farcaş, Anne-Catherine Servais, Caroline Lamalle, Patrice Chiap, Lionel Pochet

Electrophoresis· January 2016

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Correction to Deciphering the Mechanism of Carbonic Anhydrase Inhibition with Coumarins and Thiocoumarins.
Alfonso Maresca, Claudia Temperini, Lionel Pochet, Bernard Masereel, Andrea Scozzafava

J Med Chem· July 2015

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3D-QSAR, design, synthesis and characterization of trisubstituted harmine derivatives with in vitro antiproliferative properties.
Céline Meinguet, Céline Bruyère, Raphaël Frédérick, Véronique Mathieu, Christelle Vancraeynest, Lionel Pochet

Eur J Med Chem· April 2015

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Thiosemicarbazide, a fragment with promising indolamine-2,3-dioxygenase (IDO) inhibition properties.
Silvia Serra, Laurence Moineaux, Christelle Vancraeynest, Bernard Masereel, Johan Wouters, Lionel Pochet

Eur J Med Chem· July 2014

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Determination of inhibitory potency of argatroban toward thrombin by electrophoretically mediated microanalysis.
Lionel Pochet, Anne-Catherine Servais, Elena Farcas, Virginie Bettonville, Charlotte Bouckaert

Talanta· November 2013

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