Publications by authors named "Lisa A Lewis"

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The gonococcal vaccine candidate antigen NGO1701 is a N. gonorrhoeae periplasmic copper storage protein.
Shea K Roe, Rafał Mazgaj, Tianmou Zhu, Mariam Esmaeeli, Lisa A Lewis

PLoS Pathog· October 2025

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The gonococcal vaccine candidate antigen NGO1701 is a periplasmic copper storage protein.
Shea K Roe, Rafał Mazgaj, Tianmou Zhu, Mariam Esmaeeli, Lisa A Lewis

bioRxiv· May 2025

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Preclinical efficacy of a cell division protein candidate gonococcal vaccine identified by artificial intelligence.
Sunita Gulati, Andreas Holm Mattsson, Sophie Schussek, Bo Zheng, Rosane B DeOliveira, Lisa A Lewis

mBio· December 2023

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Alternative pathway amplification and infections.
Jutamas Shaughnessy, Aleyo Chabeda, Lisa A Lewis, Sanjay Ram

Immunol Rev· January 2023

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Neisseria gonorrhoeae Infection in Women Increases With Rising Gonococcal Burdens in Partners: Chlamydia Coinfection in Women Increases Gonococcal Burden.
Xiaohong Su, Wenjing Le, Xiaofeng Zhu, Sai Li, Baoxi Wang, Lisa A Lewis

J Infect Dis· December 2022

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An optimized Factor H-Fc fusion protein against multidrug-resistant .
Jutamas Shaughnessy, Aleyo Chabeda, Y Tran, Bo Zheng, Nancy Nowak, Lisa A Lewis

Front Immunol· September 2022

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Efficacy of an Experimental Gonococcal Lipooligosaccharide Mimitope Vaccine Requires Terminal Complement.
Lisa A Lewis, Sunita Gulati, Wioleta M Zelek, B Paul Morgan, Wen-Chao Song

J Infect Dis· May 2022

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Efficacy of Antigonococcal CMP-Nonulosonate Therapeutics Require Cathelicidins.
Sunita Gulati, Ian C Schoenhofen, Theresa Lindhout-Djukic, Lisa A Lewis, Iesha Y Moustafa

J Infect Dis· October 2020

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Complement interactions with the pathogenic Neisseriae: clinical features, deficiency states, and evasion mechanisms.
Lisa A Lewis, Sanjay Ram

FEBS Lett· August 2020

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Therapeutic CMP-Nonulosonates against Multidrug-Resistant .
Sunita Gulati, Ian C Schoenhofen, Theresa Lindhout-Djukic, Melissa J Schur, Corinna S Landig, Lisa A Lewis

J Immunol· June 2020

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Effect of a C1s Inhibitor on the Efficacy of Anti-Capsular Antibodies against and .
Lisa A Lewis, Sandip Panicker, Rosane B DeOliveira, Graham C Parry, Sanjay Ram

Immunohorizons· November 2019

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A Meningococcal Outer Membrane Vesicle Vaccine with Overexpressed Mutant FHbp Elicits Higher Protective Antibody Responses in Infant Rhesus Macaques than a Licensed Serogroup B Vaccine.
Peter T Beernink, Vianca Vianzon, Lisa A Lewis, Gregory R Moe, Dan M Granoff

mBio· June 2019

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A Meningococcal Native Outer Membrane Vesicle Vaccine With Attenuated Endotoxin and Overexpressed Factor H Binding Protein Elicits Gonococcal Bactericidal Antibodies.
Peter T Beernink, Emma Ispasanie, Lisa A Lewis, Sanjay Ram, Gregory R Moe

J Infect Dis· March 2019

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Role of Gonococcal Neisserial Surface Protein A (NspA) in Serum Resistance and Comparison of Its Factor H Binding Properties with Those of Its Meningococcal Counterpart.
Lisa A Lewis, Peter A Rice, Sanjay Ram

Infect Immun· February 2019

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Human Factor H Domains 6 and 7 Fused to IgG1 Fc Are Immunotherapeutic against .
Jutamas Shaughnessy, Lisa A Lewis, Bo Zheng, Caleb Carr, Isaac Bass

J Immunol· November 2018

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A Novel Sialylation Site on Neisseria gonorrhoeae Lipooligosaccharide Links Heptose II Lactose Expression with Pathogenicity.
Sanjay Ram, Sunita Gulati, Lisa A Lewis, Srinjoy Chakraborti, Bo Zheng

Infect Immun· August 2018

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Gonococcal lipooligosaccharide sialylation: virulence factor and target for novel immunotherapeutics.
Sanjay Ram, Jutamas Shaughnessy, Rosane B de Oliveira, Lisa A Lewis, Sunita Gulati

Pathog Dis· June 2017

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Utilizing complement evasion strategies to design complement-based antibacterial immunotherapeutics: Lessons from the pathogenic Neisseriae.
Sanjay Ram, Jutamas Shaughnessy, Rosane B DeOliveira, Lisa A Lewis, Sunita Gulati

Immunobiology· October 2016

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Phase-Variable Heptose I Glycan Extensions Modulate Efficacy of 2C7 Vaccine Antibody Directed against Neisseria gonorrhoeae Lipooligosaccharide.
Srinjoy Chakraborti, Lisa A Lewis, Andrew D Cox, Frank St Michael, Jianjun Li

J Immunol· June 2016

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A Novel Factor H-Fc Chimeric Immunotherapeutic Molecule against Neisseria gonorrhoeae.
Jutamas Shaughnessy, Sunita Gulati, Sarika Agarwal, Magnus Unemo, Makoto Ohnishi, Lisa A Lewis

J Immunol· February 2016

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Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics.
Sunita Gulati, Ian C Schoenhofen, Dennis M Whitfield, Andrew D Cox, Jianjun Li, Lisa A Lewis

PLoS Pathog· December 2015

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Characterization of the novel DNA gyrase inhibitor AZD0914: low resistance potential and lack of cross-resistance in Neisseria gonorrhoeae.
Richard A Alm, Sushmita D Lahiri, Amy Kutschke, Linda G Otterson, Robert E McLaughlin, Lisa A Lewis

Antimicrob Agents Chemother· March 2015

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α-2,3-sialyltransferase expression level impacts the kinetics of lipooligosaccharide sialylation, complement resistance, and the ability of Neisseria gonorrhoeae to colonize the murine genital tract.
Lisa A Lewis, Sunita Gulati, Elizabeth Burrowes, Bo Zheng, Sanjay Ram

mBio· February 2015

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Inhibition of the alternative pathway of nonhuman infant complement by porin B2 contributes to virulence of Neisseria meningitidis in the infant rat model.
Lisa A Lewis, David M Vu, Dan M Granoff, Sanjay Ram

Infect Immun· June 2014

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Factor H-dependent alternative pathway inhibition mediated by porin B contributes to virulence of Neisseria meningitidis.
Lisa A Lewis, David M Vu, Shreekant Vasudhev, Jutamas Shaughnessy, Dan M Granoff

mBio· October 2013

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