Publications by authors named "Lisa Goebel"

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Targeting oncogenic KRasG13C with nucleotide-based covalent inhibitors.
Lisa Goebel, Tonia Kirschner, Sandra Koska, Amrita Rai, Petra Janning

Elife· March 2023

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KRasG12C inhibitors in clinical trials: a short historical perspective.
Lisa Goebel, Matthias P Müller, Roger S Goody, Daniel Rauh

RSC Med Chem· July 2020

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Characterization of Covalent Pyrazolopyrimidine-MKK7 Complexes and a Report on a Unique DFG-in/Leu-in Conformation of Mitogen-Activated Protein Kinase Kinase 7 (MKK7).
Patrik Wolle, Julian Engel, Steven Smith, Lisa Goebel, Elisabeth Hennes

J Med Chem· June 2019

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POLE Score: a comprehensive profiling of programmed death 1 ligand 1 expression in pancreatic ductal adenocarcinoma.
Sascha Rahn, Sandra Krüger, Ruben Mennrich, Lisa Goebel, Daniela Wesch

Oncotarget· February 2019

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Structure-Guided Development of Covalent and Mutant-Selective Pyrazolopyrimidines to Target T790M Drug Resistance in Epidermal Growth Factor Receptor.
Julian Engel, Steven Smith, Jonas Lategahn, Hannah L Tumbrink, Lisa Goebel

J Med Chem· September 2017

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Comparative characterization of stroma cells and ductal epithelium in chronic pancreatitis and pancreatic ductal adenocarcinoma.
Ole Helm, Ruben Mennrich, Domantas Petrick, Lisa Goebel, Sandra Freitag-Wolf

PLoS One· June 2015

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CD4 T cells potently induce epithelial-mesenchymal-transition in premalignant and malignant pancreatic ductal epithelial cells-novel implications of CD4 T cells in pancreatic cancer development.
Lisa Goebel, Evelin Grage-Griebenow, Artur Gorys, Ole Helm, Geeske Genrich

Oncoimmunology· April 2015

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L1CAM promotes enrichment of immunosuppressive T cells in human pancreatic cancer correlating with malignant progression.
Evelin Grage-Griebenow, Elfi Jerg, Artur Gorys, Daniel Wicklein, Daniela Wesch, Lisa Goebel

Mol Oncol· July 2014

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