Publications by authors named "Lisa Iacono"

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Physiologically-based pharmacokinetic modelling of a CYP2C19 substrate, BMS-823778, utilizing pharmacogenetic data.
Jiachang Gong, Lisa Iacono, Ramaswamy A Iyer, William G Humphreys, Ming Zheng

Br J Clin Pharmacol· June 2018

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Clinical Pharmacokinetics and the Impact of Genetic Polymorphism on a CYP2C19 Substrate, BMS-823778, in Healthy Subjects.
Jiachang Gong, Lars Hansen, Lisa Iacono

Drug Metab Dispos· March 2018

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Clinical significance of CYP2C19 polymorphisms on the metabolism and pharmacokinetics of 11β-hydroxysteroid dehydrogenase type-1 inhibitor BMS-823778.
Yaofeng Cheng, Lifei Wang, Lisa Iacono, Donglu Zhang, Weiqi Chen

Br J Clin Pharmacol· January 2018

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A validated enantioselective LC-MS/MS assay for quantification of a major chiral metabolite of an achiral 11-β-hydroxysteroid-dehydrogenase 1 inhibitor in human plasma: Application to a clinical pharmacokinetic study.
Michael T Furlong, Qin C Ji, Lisa Iacono, Oanh Dang, Marzena Noren

J Chromatogr B Analyt Technol Biomed Life Sci· June 2016

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A phase I study of oral ixabepilone in patients with advanced solid tumors.
John F Deeken, John L Marshall, Michael J Pishvaian, Jimmy Hwang, Christoph M Ahlers, Lisa Iacono

Cancer Chemother Pharmacol· May 2014

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Phase I and pharmacokinetic study of CT-322 (BMS-844203), a targeted Adnectin inhibitor of VEGFR-2 based on a domain of human fibronectin.
Anthony W Tolcher, Christopher J Sweeney, Kyri Papadopoulos, Amita Patnaik, Elena G Chiorean, Lisa Iacono

Clin Cancer Res· January 2011

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Liquid chromatography and tandem mass spectrometry for the quantitative determination of ixabepilone (BMS-247550, Ixempra) in human plasma: method validation, overcoming curve splitting issues and eliminating chromatographic interferences from degradants.
Xiaohui Sophia Xu, Jianing Zeng, William Mylott, Mark Arnold, James Waltrip, Lisa Iacono

J Chromatogr B Analyt Technol Biomed Life Sci· February 2010

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The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.
Sanjay Goel, Marvin Cohen, S Nilgün Cömezoglu, Lionel Perrin, François André, Lisa Iacono

Clin Cancer Res· May 2008

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Population pharmacokinetic analysis of topotecan in pediatric cancer patients.
Paula Schaiquevich, John C Panetta, Lisa C Iacono, Burgess B Freeman, Victor M Santana

Clin Cancer Res· November 2007

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Pharmacokinetics and pharmacodynamics of intravenous epoetin alfa in children with cancer.
Burgess B Freeman, Pamela Hinds, Lisa C Iacono, Bassem I Razzouk, Elizabeth Burghen

Pediatr Blood Cancer· October 2006

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Development and validation of limited sampling models for topotecan lactone pharmacokinetic studies in children.
P Kellie Turner, Lisa C Iacono, John C Panetta, Victor M Santana, Najat C Daw

Cancer Chemother Pharmacol· April 2006

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Using plasma topotecan pharmacokinetics to estimate topotecan exposure in cerebrospinal fluid of children with medulloblastoma.
Burgess B Freeman, Lisa C Iacono, John C Panetta, Amar Gajjar, Clinton F Stewart

Neuro Oncol· April 2006

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Temozolomide after radiotherapy for newly diagnosed high-grade glioma and unfavorable low-grade glioma in children.
Alberto Broniscer, Murali Chintagumpala, Maryam Fouladi, Matthew J Krasin, Mehmet Kocak, Lisa C Iacono

J Neurooncol· February 2006

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Cyclophosphamide disposition in an anephric child.
Jeannine S McCune, Denise Adams, Alan C Homans, Ann Guillot, Lisa Iacono

Pediatr Blood Cancer· January 2006

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Activation and antitumor activity of CPT-11 in plasma esterase-deficient mice.
Christopher L Morton, Lisa Iacono, Janice L Hyatt, Kody R Taylor, Pamela J Cheshire

Cancer Chemother Pharmacol· December 2005

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Phase I and pharmacokinetic study of gefitinib in children with refractory solid tumors: a Children's Oncology Group Study.
Najat C Daw, Wayne L Furman, Clinton F Stewart, Lisa C Iacono, Mark Krailo

J Clin Oncol· September 2005

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Development of a pharmacokinetic limited sampling model for temozolomide and its active metabolite MTIC.
Mark N Kirstein, John C Panetta, Amar Gajjar, Geeta Nair, Lisa C Iacono

Cancer Chemother Pharmacol· May 2005

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Role of temozolomide after radiotherapy for newly diagnosed diffuse brainstem glioma in children: results of a multiinstitutional study (SJHG-98).
Alberto Broniscer, Lisa Iacono, Murali Chintagumpala, Maryam Fouladi, Dana Wallace

Cancer· January 2005

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Topoisomerase I interactive agents.
P Kellie Turner, Lisa C Iacono, Clinton F Stewart

Cancer Chemother Biol Response Modif· September 2004

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Topotecan disposition in an anephric child.
Lisa C Iacono, Denise Adams, Alan C Homans, Ann Guillot, Jeannine S McCune

J Pediatr Hematol Oncol· September 2004

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Results of a phase II upfront window of pharmacokinetically guided topotecan in high-risk medulloblastoma and supratentorial primitive neuroectodermal tumor.
Clinton F Stewart, Lisa C Iacono, Murali Chintagumpala, Stewart J Kellie, David Ashley

J Clin Oncol· August 2004

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Phase I and pharmacokinetic study of topotecan administered orally once daily for 5 days for 2 consecutive weeks to pediatric patients with refractory solid tumors.
Najat C Daw, Victor M Santana, Lisa C Iacono, Wayne L Furman, Dana R Hawkins

J Clin Oncol· March 2004

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Phase I trial of temozolomide and protracted irinotecan in pediatric patients with refractory solid tumors.
Lars M Wagner, Kristine R Crews, Lisa C Iacono, Peter J Houghton, Christine E Fuller

Clin Cancer Res· February 2004

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The importance of pharmacokinetic limited sampling models for childhood cancer drug development.
J Carl Panetta, Lisa C Iacono, Peter C Adamson, Clinton F Stewart

Clin Cancer Res· November 2003

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Determination of plasma topotecan and its metabolite N-desmethyl topotecan as both lactone and total form by reversed-phase liquid chromatography with fluorescence detection.
Feng Bai, Mark N Kirstein, Suzan K Hanna, Lisa C Iacono, Brad Johnston

J Chromatogr B Analyt Technol Biomed Life Sci· February 2003

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