Publications by authors named "Lisa Strasser"

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Detection of host cell microprotein impurities in antibody drug products.
Ioanna Tzani, Marina Castro-Rivadeneyra, Paul Kelly, Lisa Strasser, Lin Zhang

Nat Commun· October 2024

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A Direct Comparison of rAAV5 Variants Derived from the Baculovirus Expression System Using LC-MS Workflows Demonstrates Key Differences in Overall Production Yield, Product Quality and Vector Efficiency.
Felipe Guapo, Nicholas Donohue, Lisa Strasser, Stefano Boi, Florian Füssl

Int J Mol Sci· February 2024

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CAR Gene Delivery by T-cell Targeted Lentiviral Vectors is Enhanced by Rapamycin Induced Reduction of Antiviral Mechanisms.
Filippos T Charitidis, Elham Adabi, Naphang Ho, Angela H Braun, Ciara Tierney, Lisa Strasser

Adv Sci (Weinh)· December 2023

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Development of a Rapid Adeno-Associated Virus (AAV) Identity Testing Platform through Comprehensive Intact Mass Analysis of Full-Length AAV Capsid Proteins.
Josh Smith, Felipe Guapo, Lisa Strasser, Silvia Millán-Martín, Steven G Milian

J Proteome Res· December 2023

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Mass spectrometry friendly pH-gradient anion exchange chromatography for the separation of full and empty adeno-associated virus (AAV) capsids.
Felipe Guapo, Florian Füssl, Lisa Strasser, Jonathan Bones

Anal Methods· November 2023

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Exploring Charge-Detection Mass Spectrometry on Chromatographic Time Scales.
Lisa Strasser, Florian Füssl, Tomos E Morgan, Sara Carillo, Jonathan Bones

Anal Chem· October 2023

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SP3-based host cell protein monitoring in AAV-based gene therapy products using LC-MS/MS.
Josh Smith, Lisa Strasser, Felipe Guapo, Steven G Milian, Richard O Snyder

Eur J Pharm Biopharm· August 2023

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Whole-cell energy modeling reveals quantitative changes of predicted energy flows in RAS mutant cancer cell lines.
Thomas Sevrin, Lisa Strasser, Camille Ternet, Philipp Junk, Miriam Caffarini

iScience· February 2023

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Fast and efficient digestion of adeno associated virus (AAV) capsid proteins for liquid chromatography mass spectrometry (LC-MS) based peptide mapping and post translational modification analysis (PTMs).
Felipe Guapo, Lisa Strasser, Silvia Millán-Martín, Ian Anderson, Jonathan Bones

J Pharm Biomed Anal· January 2022

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Detection and quantitation of host cell proteins in monoclonal antibody drug products using automated sample preparation and data-independent acquisition LC-MS/MS.
Lisa Strasser, Giorgio Oliviero, Craig Jakes, Izabela Zaborowska, Patrick Floris

J Pharm Anal· December 2021

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Native LC-MS for capturing quality attributes of biopharmaceuticals on the intact protein level.
Florian Füssl, Lisa Strasser, Sara Carillo, Jonathan Bones

Curr Opin Biotechnol· October 2021

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Proteomic Landscape of Adeno-Associated Virus (AAV)-Producing HEK293 Cells.
Lisa Strasser, Stefano Boi, Felipe Guapo, Nicholas Donohue, Niall Barron

Int J Mol Sci· October 2021

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A Native Mass Spectrometry-Based Assay for Rapid Assessment of the Empty:Full Capsid Ratio in Adeno-Associated Virus Gene Therapy Products.
Lisa Strasser, Tomos E Morgan, Felipe Guapo, Florian Füssl, Daniel Forsey

Anal Chem· September 2021

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Design of Phl p 6 Variants With Altered Fold-Stability Significantly Impacts Antigen Processing, Immunogenicity and Immune Polarization.
Petra Winter, Stefan Stubenvoll, Sandra Scheiblhofer, Isabella A Joubert, Lisa Strasser

Front Immunol· April 2021

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Proteomic Profiling of IgG1 Producing CHO Cells Using LC/LC-SPS-MS: The Effects of Bioprocessing Conditions on Productivity and Product Quality.
Lisa Strasser, Amy Farrell, Jenny T C Ho, Kai Scheffler, Ken Cook

Front Bioeng Biotechnol· April 2021

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Platform independent protein-based cell-of-origin subtyping of diffuse large B-cell lymphoma in formalin-fixed paraffin-embedded tissue.
Jörg Reinders, Michael Altenbuchinger, Katharina Limm, Philipp Schwarzfischer, Tamara Scheidt, Lisa Strasser

Sci Rep· May 2020

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