Publications by authors named "Lisa Woolhiser"

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Correction: Evaluating the efficacy of HRZE-based regimens in a high-burden murine model: a back-translational assessment of rifamycins and moxifloxacin substitutions in tuberculosis treatment.
Jason E Cummings, Lisa K Woolhiser, Vincent Guglielmi, Machenzie Wernsman, Ashley Romano

Front Pharmacol· December 2025

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Evaluating the efficacy of HRZE-based regimens in a high-burden murine model: a back-translational assessment of rifamycins and moxifloxacin substitutions in tuberculosis treatment.
Jason E Cummings, Lisa K Woolhiser, Vincent Guglielmi, Machenzie Wernsman, Ashley Romano

Front Pharmacol· October 2025

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SuFEx-based antitubercular compound irreversibly inhibits Pks13.
Inna V Krieger, Paridhi Sukheja, Baiyuan Yang, Su Tang, Daniel Selle, Lisa K Woolhiser

Nature· September 2025

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Erratum for Peroutka-Bigus et al., "Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease".
Nathan Peroutka-Bigus, Elizabeth J Brooks, Michelle E Ramey, Hope D'Erasmo, Jackie P Ernest, Lisa K Woolhiser

Antimicrob Agents Chemother· August 2025

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Establishing translational performance standards for TB therapy using rifampicin-based regimens in a male and female high-burden murine model.
Jason E Cummings, Lisa Woolhiser, Barbara Graham, Gregory T Robertson, M Nurul Islam

BMC Microbiol· July 2025

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Contribution of front-line, standard-of-care drugs to bactericidal responses, resistance emergence, and cure in murine models of easy- or hard-to-treat tuberculosis disease.
Nathan Peroutka-Bigus, Elizabeth J Brooks, Michelle E Ramey, Hope D'Erasmo, Jackie P Ernest, Lisa K Woolhiser

Antimicrob Agents Chemother· May 2025

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Comparative Analysis of Pharmacodynamics in the C3HeB/FeJ Mouse Tuberculosis Model for DprE1 Inhibitors TBA-7371, PBTZ169, and OPC-167832.
Gregory T Robertson, Michelle E Ramey, Lisa M Massoudi, Claire L Carter, Matt Zimmerman, Lisa K Woolhiser

Antimicrob Agents Chemother· October 2021

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Intracellular and in vivo evaluation of imidazo[2,1-b]thiazole-5-carboxamide anti-tuberculosis compounds.
Garrett C Moraski, Nathalie Deboosère, Kate L Marshall, Heath A Weaver, Alexandre Vandeputte, Lisa Woolhiser

PLoS One· April 2020

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Pyrazolo[1,5- a]pyridine Inhibitor of the Respiratory Cytochrome bcc Complex for the Treatment of Drug-Resistant Tuberculosis.
Xiaoyun Lu, Zoe Williams, Kiel Hards, Jian Tang, Chen-Yi Cheung, Lisa Woolhiser

ACS Infect Dis· February 2019

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Discovery of a cofactor-independent inhibitor of InhA.
Yi Xia, Yasheen Zhou, David S Carter, Matthew B McNeil, Wai Choi, Lisa K Woolhiser

Life Sci Alliance· June 2018

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Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
Anup Aggarwal, Maloy K Parai, Nishant Shetty, Deeann Wallis, Lisa Woolhiser

Cell· July 2017

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Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase.
Andrés Palencia, Xianfeng Li, Wei Bu, Wai Choi, Charles Z Ding, Lisa Woolhiser

Antimicrob Agents Chemother· October 2016

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Pentacyclic nitrofurans with in vivo efficacy and activity against nonreplicating Mycobacterium tuberculosis.
Rakesh, David F Bruhn, Michael S Scherman, Lisa K Woolhiser, Dora B Madhura

PLoS One· November 2014

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Bayesian models leveraging bioactivity and cytotoxicity information for drug discovery.
Sean Ekins, Robert C Reynolds, Hiyun Kim, Mi-Sun Koo, Marilyn Ekonomidis, Lisa K Woolhiser

Chem Biol· March 2013

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Mouse model for efficacy testing of antituberculosis agents via intrapulmonary delivery.
Mercedes Gonzalez-Juarrero, Lisa K Woolhiser, Elizabeth Brooks, Mary Ann DeGroote, Anne J Lenaerts

Antimicrob Agents Chemother· July 2012

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Effects of P-MAPA Immunomodulator on Toll-Like Receptors and p53: Potential Therapeutic Strategies for Infectious Diseases and Cancer.
Wagner J Fávaro, Odilon S Nunes, Fabio Rf Seiva, Iseu S Nunes, Lisa K Woolhiser

Infect Agent Cancer· June 2012

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Importance of confirming data on the in vivo efficacy of novel antibacterial drug regimens against various strains of Mycobacterium tuberculosis.
Mary A De Groote, Veronica Gruppo, Lisa K Woolhiser, Ian M Orme, Janet C Gilliland

Antimicrob Agents Chemother· February 2012

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A novel metabolite of antituberculosis therapy demonstrates host activation of isoniazid and formation of the isoniazid-NAD+ adduct.
Sebabrata Mahapatra, Lisa K Woolhiser, Anne J Lenaerts, John L Johnson, Kathleen D Eisenach

Antimicrob Agents Chemother· January 2012

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Novel pyridopyrazine and pyrimidothiazine derivatives as FtsZ inhibitors.
Bini Mathew, Shefali Srivastava, Larry J Ross, William J Suling, E Lucile White, Lisa K Woolhiser

Bioorg Med Chem· December 2011

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Comparative studies evaluating mouse models used for efficacy testing of experimental drugs against Mycobacterium tuberculosis.
Mary A De Groote, Janet C Gilliland, Colby L Wells, Elizabeth J Brooks, Lisa K Woolhiser

Antimicrob Agents Chemother· March 2011

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Discovery, synthesis, and biological evaluation of piperidinol analogs with anti-tuberculosis activity.
Dianqing Sun, Michael S Scherman, Victoria Jones, Julian G Hurdle, Lisa K Woolhiser

Bioorg Med Chem· May 2009

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Testing of experimental compounds in a relapse model of tuberculosis using granulocyte-macrophage colony-stimulating factor gene-disrupted mice.
Lisa K Woolhiser, Donald R Hoff, Karen S Marietta, Ian M Orme, Anne J Lenaerts

Antimicrob Agents Chemother· January 2009

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Evaluation of a 2-pyridone, KRQ-10018, against Mycobacterium tuberculosis in vitro and in vivo.
Anne J Lenaerts, Casey Bitting, Lisa Woolhiser, Veronica Gruppo, Karen S Marietta

Antimicrob Agents Chemother· April 2008

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In vivo adaptation of the Wayne model of latent tuberculosis.
Lisa Woolhiser, Marcela Henao Tamayo, Baolin Wang, Veronica Gruppo, John T Belisle

Infect Immun· May 2007

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