Publications by authors named "Lixin Wan"

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Tecotabart vedotin in Claudin 18.2-positive advanced gastric/gastroesophageal junction cancer: A Bayesian phase 1/2 clinical trial.
Chunmei Bai, Yi Zheng, Meili Sun, Jieer Ying, Fuxiang Zhou, Lixin Wan, Qi Wang, Baoqing Wang

Eur J Cancer· November 2025

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Neutralization Mechanism of a HipA-like Toxin Targeting Isoleucyl-tRNA Synthetase.
Si-Ping Zhang, Ying-Jie Song, Yi-Ping Ye, Zi-Rui Ye, Fu-Lin Yang, Li-Xin Wan, Yong Wang

J Mol Biol· November 2025

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Targeting TFAM downregulation mediated mtDNA-NLRP3 pathway suppresses TAM infiltration and HCC progression.
Jing Zhao, Mengmeng Cui, Xiaojuan Yao, Zhixiong Jiang, Lixia Qi, Lixin Wan

Oncogene· September 2025

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Correction: SCFβ-TRCP suppresses angiogenesis and thyroid cancer cell migration by promoting ubiquitination and destruction of VEGF receptor 2.
Shavali Shaik, Carmelo Nucera, Hiroyuki Inuzuka, Daming Gao, Maija Garnaas, Lixin Wan

J Exp Med· September 2025

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Phosphorylation of EZH2 by AMPK Suppresses PRC2 Methyltransferase Activity and Oncogenic Function.
Lixin Wan, Kexin Xu, Yongkun Wei, Jinfang Zhang, Tao Han, Yao Vickie Wang

Mol Cell· August 2025

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Linear ubiquitination of p31 by HOIP couples cytokine response with mitotic regulation.
Yifeng Gao, Qing Yin, Yaser Gamallat, Michael G Grant, Aidan H Snell, Lixin Wan

Cell Biosci· June 2025

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Targeting Drp1 inhibits ESCC progression via the ROS-PGC1-α-Nrf1/2 pathway.
Zhixiong Jiang, Yating Yang, Jinchi Zhou, Xin Li, Qingqing Meng, Huizhen Wang, Lixin Wan

J Transl Med· June 2025

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SCF Modulates the NFκB Signaling Pathway by Targeting NFκB2 for Ubiquitination and Destruction.
Hidefumi Fukushima, Akinobu Matsumoto, Hiroyuki Inuzuka, Bo Zhai, Alan W Lau, Lixin Wan

Cell Rep· May 2025

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First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial.
Lin Shen, Yanqiao Zhang, Ziyu Li, Xiaotian Zhang, Xiangyu Gao, Yusheng Wang, Lixin Wan, Weibo Wang, Zhenghua Wang, Ying Wang, Daqing Wang, Meiqing Wang, Zejun Wang, Zhongmin Maxwell Wang

Nat Med· April 2025

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Author Correction: First-line cadonilimab plus chemotherapy in HER2-negative advanced gastric or gastroesophageal junction adenocarcinoma: a randomized, double-blind, phase 3 trial.
Lin Shen, Yanqiao Zhang, Ziyu Li, Xiaotian Zhang, Xiangyu Gao, Yusheng Wang, Lixin Wan, Weibo Wang, Zhenghua Wang, Ying Wang, Daqing Wang, Meiqing Wang, Zejun Wang, Zhongmin Maxwell Wang

Nat Med· April 2025

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Effectiveness, safety, and patterns of use of camrelizumab in advanced esophageal cancer: an individual patient data pooled analysis of 987 patients from three prospective cohort studies.
Zhihao Lu, Guoping Sun, Jiancheng Li, Jun Zhao, Zishu Wang, Junsheng Wang, Yusheng Wang, Chen Wang, Lixin Wan

Cancer Immunol Immunother· March 2025

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Retrospective analysis of disease characteristics and treatment patterns among patients with esophageal cancer across 14 surgically represented centers.
Zhihao Lu, Mingfei Geng, Yongtao Han, Jianzhong Cao, Jun Wang, Lixin Wan, Wenran Wang

Cancer Biol Med· January 2025

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The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes.
Amanda K Riley, Michael Grant, Aidan Snell, Elizabeth Cromwell, Athea Vichas, Lixin Wan

iScience· August 2024

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Capecitabine or Capecitabine Plus Oxaliplatin Versus Fluorouracil Plus Cisplatin in Definitive Concurrent Chemoradiotherapy for Locally Advanced Esophageal Squamous Cell Carcinoma (CRTCOESC): A Multicenter, Randomized, Open-Label, Phase 3 Trial.
Ruinuo Jia, Tanyou Shan, Anping Zheng, Yaowen Zhang, Ping Lu, Feng Wang, Wanying Li, Qiming Wang, Xinshuai Wang, Ziqi Wang, Lixin Wan

J Clin Oncol· July 2024

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Association between composite dietary antioxidant index and kidney stone prevalence in adults: data from National Health and Nutrition Examination Survey (NHANES, 2007-2018).
Qixin Duan, Han Huang, Shuang Zhang, Yang Wang, Dongming Lu, Lixin Wan

Front Nutr· May 2024

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Breaking NGF-TrkA immunosuppression in melanoma sensitizes immunotherapy for durable memory T cell protection.
Tao Yin, Guoping Wang, Liuyang Wang, Poorva Mudgal, Ergang Wang, Lixin Wan, Xiao-Fan Wang

Nat Immunol· February 2024

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An Epigenomic fingerprint of human cancers by landscape interrogation of super enhancers at the constituent level.
Xiang Liu, Nancy Gillis, Chang Jiang, Anthony McCofie, Timothy I Shaw, Lixin Wan

PLoS Comput Biol· February 2024

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Comparison of positive and negative gastric cancer via multi-omics analysis.
Fumei Shang, Yinghao Cao, Lixin Wan, Zhonghai Ren, Xinghao Wang

mBio· December 2023

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The deubiquitinase USP9X regulates RIT1 protein abundance and oncogenic phenotypes.
Amanda K Riley, Michael Grant, Aidan Snell, Athea Vichas, Sitapriya Moorthi, Lixin Wan

bioRxiv· December 2023

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AIFM2 promotes hepatocellular carcinoma metastasis by enhancing mitochondrial biogenesis through activation of SIRT1/PGC-1α signaling.
Sanxing Guo, Fengying Li, Yixuan Liang, Yufei Zheng, Yingyi Mo, Lixin Wan

Oncogenesis· September 2023

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TFAM downregulation promotes autophagy and ESCC survival through mtDNA stress-mediated STING pathway.
Yujia Li, Qi Yang, Hui Chen, Xiaotian Yang, Jingru Han, Lixin Wan, Yanming Wang

Oncogene· July 2022

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[Adaptability of to sewage sludge and its characteristics of nutrient and heavy metal uptake and accumulation].
Jia-Yi Feng, Ke-Jin Ruan, Si-Ning Su, Xue-Ping Zhang, Dao-Ming Wu, Li-Xin Wan

Ying Yong Sheng Tai Xue Bao· June 2022

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CircATIC inhibits esophageal carcinoma progression and promotes radiosensitivity by elevating RHCG through sponging miR-10-3p.
Kai Zhang, Ruitai Fan, Deyao Zhao, Peipei Liu, Zheng Yang, Yang Wang, Lixin Wan

Thorac Cancer· April 2022

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Increased Drp1 promotes autophagy and ESCC progression by mtDNA stress mediated cGAS-STING pathway.
Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Jiaxin Wang, Shaogui Wan, Yanming Wang

J Exp Clin Cancer Res· February 2022

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Acetylation-dependent regulation of BRAF oncogenic function.
Xiangpeng Dai, Xiaoling Zhang, Qing Yin, Jia Hu, Jianping Guo, Lixin Wan

Cell Rep· January 2022

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