Publications by authors named "Liyou Han"

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Inhibition of γ-glutamyl transferase suppresses airway hyperresponsiveness and airway inflammation in a mouse model of steroid resistant asthma exacerbation.
Cancan Zhang, Huisha Xu, Keilah G Netto, Leon A Sokulsky, Yiyan Miao, Liyou Han, Lirong Zhang, Guojun Zhang

Front Immunol· June 2023

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Phosphonate-based irreversible inhibitors of human γ-glutamyl transpeptidase (GGT). GGsTop is a non-toxic and highly selective inhibitor with critical electrostatic interaction with an active-site residue Lys562 for enhanced inhibitory activity.
Akane Kamiyama, Mado Nakajima, Liyou Han, Kei Wada, Masaharu Mizutani

Bioorg Med Chem· November 2016

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Glutathione-analogous peptidyl phosphorus esters as mechanism-based inhibitors of γ-glutamyl transpeptidase for probing cysteinyl-glycine binding site.
Mado Nakajima, Bunta Watanabe, Liyou Han, Bun-Ichi Shimizu, Kei Wada

Bioorg Med Chem· February 2014

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Synthesis and in-vitro antibacterial activity of 7-(3-aminopyrrolo[3,4-c]pyrazol-5(2H,4H,6H)-yl)-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid derivatives.
Xin Guo, Xiao-Guang Bai, Yi-Liang Li, Zhi-Jiao An, Le-Xing Xu, Li-you Han

Arch Pharm (Weinheim)· August 2011

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Synthesis and in vitro antibacterial activity of fluoroquinolone derivatives containing 3-(N'-alkoxycarbamimidoyl)-4-(alkoxyimino) pyrrolidines.
Qiang Guo, Lian-Shun Feng, Ming-Liang Liu, Yi-Bin Zhang, Yun Chai, Li-You Han

Eur J Med Chem· November 2010

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Design, synthesis, and evaluation of gamma-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of gamma-glutamyl transpeptidase.
Liyou Han, Jun Hiratake, Akane Kamiyama, Kanzo Sakata

Biochemistry· February 2007

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Gamma-(monophenyl)phosphono glutamate analogues as mechanism-based inhibitors of gamma-glutamyl transpeptidase.
Liyou Han, Jun Hiratake, Norihito Tachi, Hideyuki Suzuki, Hidehiko Kumagai

Bioorg Med Chem· September 2006

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