Publications by authors named "Lloyd D Fricker"

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Antidepressants and the endogenous opioid system.
Lloyd D Fricker, Aya Osman, Achla Gupta, Ivone Gomes, Lakshmi A Devi

Biochem Pharmacol· December 2025

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ProSAAS neuropeptides and receptors GPR171 and GPR83: Potential therapeutic applications for pain, anxiety, and body weight regulation.
Lloyd D Fricker, Amanda K Fakira, Erin N Bobeck, Megan Raddatz, Kelly Kim

J Pharmacol Exp Ther· June 2025

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Ketamine and Major Ketamine Metabolites Function as Allosteric Modulators of Opioid Receptors.
Ivone Gomes, Achla Gupta, Elyssa B Margolis, Lloyd D Fricker, Lakshmi A Devi

Mol Pharmacol· October 2024

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Two Different Strategies for Stabilization of Brain Tissue and Extraction of Neuropeptides.
Elva Fridjonsdottir, Anna Nilsson, Lloyd D Fricker, Per E Andrén

Methods Mol Biol· April 2024

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Quantitative Peptidomics: General Considerations.
Lloyd D Fricker

Methods Mol Biol· April 2024

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Quantitative Peptidomics Using Reductive Methylation of Amines.
Alexandre K Tashima, Leandro M de Castro, Lloyd D Fricker

Methods Mol Biol· April 2024

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Neuropeptidomics of Genetically Defined Cell Types in Mouse Brain.
Lloyd D Fricker

Methods Mol Biol· April 2024

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Current Challenges and Future Directions in Peptidomics.
Michael Schrader, Lloyd D Fricker

Methods Mol Biol· April 2024

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Mice lacking proSAAS display alterations in emotion, consummatory behavior and circadian entrainment.
Dipendra K Aryal, Ramona M Rodriguiz, Ngoc Lien Nguyen, Matthew W Pease, Daniel J Morgan, Lloyd D Fricker

Genes Brain Behav· September 2022

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Mice heterozygous for a null mutation of CPE show reduced expression of carboxypeptidase e mRNA and enzyme activity but normal physiology, behavior, and levels of neuropeptides.
Lloyd D Fricker, Mariana Lemos Duarte, Andrei Jeltyi, Lindsay Lueptow, Amanda K Fakira

Brain Res· August 2022

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Obesity, POMC, and POMC-processing Enzymes: Surprising Results From Animal Models.
Iris Lindberg, Lloyd D Fricker

Endocrinology· December 2021

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Neuropeptidomic Analysis of a Genetically Defined Cell Type in Mouse Brain and Pituitary.
Lloyd D Fricker, Alexandre K Tashima, Amanda K Fakira, Ute Hochgeschwender, William C Wetsel

Cell Chem Biol· January 2021

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Substrate Specificity and Structural Modeling of Human Carboxypeptidase Z: A Unique Protease with a Frizzled-Like Domain.
Javier Garcia-Pardo, Sebastian Tanco, Maria C Garcia-Guerrero, Sayani Dasgupta, Francesc Xavier Avilés, Lloyd D Fricker

Int J Mol Sci· November 2020

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Five Decades of Research on Opioid Peptides: Current Knowledge and Unanswered Questions.
Lloyd D Fricker, Elyssa B Margolis, Ivone Gomes, Lakshmi A Devi

Mol Pharmacol· August 2020

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Proteasome Inhibitor Drugs.
Lloyd D Fricker

Annu Rev Pharmacol Toxicol· January 2020

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Identification and characterization of RSIY-11, a novel seminal peptide derived from semenogelin-1, which acts as a neutral endopeptidase inhibitor modulating sperm motility.
Rani Fritz, Amarnath Mukherjee, Sahar Zaghi, Ilir Agalliu, Sangita Jindal, Lloyd D Fricker

J Assist Reprod Genet· September 2019

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Carboxypeptidase E and the Identification of Novel Neuropeptides as Potential Therapeutic Targets.
Lloyd D Fricker

Adv Pharmacol· July 2019

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Effect of Protein Denaturation and Enzyme Inhibitors on Proteasomal-Mediated Production of Peptides in Human Embryonic Kidney Cells.
Sayani Dasgupta, Michael A Fishman, Leandro M Castro, Alexandre K Tashima, Emer S Ferro, Lloyd D Fricker

Biomolecules· May 2019

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Orphan neuropeptides and receptors: Novel therapeutic targets.
Lloyd D Fricker, Lakshmi A Devi

Pharmacol Ther· May 2018

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Quantitative Peptidomics with Five-plex Reductive Methylation labels.
Alexandre K Tashima, Lloyd D Fricker

J Am Soc Mass Spectrom· May 2018

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Substrate specificity of human metallocarboxypeptidase D: Comparison of the two active carboxypeptidase domains.
Javier Garcia-Pardo, Sebastian Tanco, Lucía Díaz, Sayani Dasgupta, Juan Fernandez-Recio, Lloyd D Fricker

PLoS One· December 2017

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ProSAAS-derived peptides are regulated by cocaine and are required for sensitization to the locomotor effects of cocaine.
Iryna Berezniuk, Ramona M Rodriguiz, Michael L Zee, David J Marcus, John Pintar, Lloyd D Fricker

J Neurochem· November 2017

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Analysis of the Yeast Peptidome and Comparison with the Human Peptidome.
Sayani Dasgupta, Ciyu Yang, Leandro M Castro, Alexandre K Tashima, Emer S Ferro, Lloyd D Fricker

PLoS One· September 2016

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Knockdown of Carboxypeptidase A6 in Zebrafish Larvae Reduces Response to Seizure-Inducing Drugs and Causes Changes in the Level of mRNAs Encoding Signaling Molecules.
Mark William Lopes, Matthew R Sapio, Rodrigo B Leal, Lloyd D Fricker

PLoS One· August 2016

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Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.
Ivone Gomes, Erin N Bobeck, Elyssa B Margolis, Achla Gupta, Salvador Sierra, Lloyd D Fricker

Sci Signal· April 2016

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