Publications by authors named "Lluis Samaranch"

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AAV9-mediated transduction of memory circuits following convection-enhanced delivery into the olfactory bulbs.
Theodore Dimitrov, Vikas Munjal, Allison O'Brien, Matthew T Rocco, Ahmad Karkhah, Lluis Samaranch

Gene Ther· December 2025

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Efficient mammalian neuron editing using peptide-mediated CRISPR enzyme delivery.
Brigette D Manohar, Meika Travis, Vikas Munjal, Christopher M Baehr, Lily M A Rahnama, Lluis Samaranch

bioRxiv· November 2025

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GDNF gene therapy for alcohol use disorder in male non-human primates.
Matthew M Ford, Brianna E George, Victor S Van Laar, Katherine M Holleran, Jerusha Naidoo, Lluis Samaranch

Nat Med· August 2023

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Infuse-as-you-go convective delivery to enhance coverage of elongated brain targets: technical note.
Vivek Sudhakar, Jerusha Naidoo, Lluis Samaranch, John R Bringas, Russell R Lonser

J Neurosurg· August 2020

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Development of a novel frameless skull-mounted ball-joint guide array for use in image-guided neurosurgery.
Vivek Sudhakar, Amin Mahmoodi, John R Bringas, Jerusha Naidoo, Adrian Kells, Lluis Samaranch

J Neurosurg· February 2020

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Adeno-associated viral vector serotype 9-based gene therapy for Niemann-Pick disease type A.
Lluis Samaranch, Azucena Pérez-Cañamás, Beatriz Soto-Huelin, Vivek Sudhakar, Jerónimo Jurado-Arjona

Sci Transl Med· August 2019

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Cerebellomedullary Cistern Injection of Viral Vectors in Nonhuman Primates.
Lluis Samaranch, Kousaku Ohno, Waldy San Sebastian, Krystof Bankiewicz

Methods Mol Biol· July 2019

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Kinetics and MR-Based Monitoring of AAV9 Vector Delivery into Cerebrospinal Fluid of Nonhuman Primates.
Kousaku Ohno, Lluis Samaranch, Piotr Hadaczek, John R Bringas, Philip C Allen

Mol Ther Methods Clin Dev· June 2019

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Pooled-DNA target sequencing of Parkinson genes reveals novel phenotypic associations in Spanish population.
Monica Diez-Fairen, Bruno A Benitez, Sara Ortega-Cubero, Oswaldo Lorenzo-Betancor, Carlos Cruchaga, Lluis Samaranch

Neurobiol Aging· October 2018

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Extensive Transduction and Enhanced Spread of a Modified AAV2 Capsid in the Non-human Primate CNS.
Jerusha Naidoo, Lisa M Stanek, Kousaku Ohno, Savanah Trewman, Lluis Samaranch

Mol Ther· October 2018

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MR-guided delivery of AAV2-BDNF into the entorhinal cortex of non-human primates.
Alan H Nagahara, Bayard R Wilson, Iryna Ivasyk, Imre Kovacs, Saytam Rawalji, Lluis Samaranch

Gene Ther· April 2018

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Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus.
Azadeh Yazdan-Shahmorad, Nan Tian, Viktor Kharazia, Lluis Samaranch, Adrian Kells

J Neurosci Methods· January 2018

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Depletion of AADC activity in caudate nucleus and putamen of Parkinson's disease patients; implications for ongoing AAV2-AADC gene therapy trial.
Agnieszka Ciesielska, Lluis Samaranch, Waldy San Sebastian, Dennis W Dickson, Samuel Goldman

PLoS One· August 2017

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Validation of antibodies for neuroanatomical localization of the P2Y receptor in macaque brain.
Karin Dreisig, Matilda Degn, Louise Sund, Piotr Hadaczek, Lluis Samaranch

J Chem Neuroanat· December 2016

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AAV viral vector delivery to the brain by shape-conforming MR-guided infusions.
Krystof S Bankiewicz, Vivek Sudhakar, Lluis Samaranch, Waldy San Sebastian, John Bringas

J Control Release· October 2016

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Widespread AAV1- and AAV2-mediated transgene expression in the nonhuman primate brain: implications for Huntington's disease.
Piotr Hadaczek, Lisa Stanek, Agnieszka Ciesielska, Vivek Sudhakar, Lluis Samaranch

Mol Ther Methods Clin Dev· July 2016

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Cerebellomedullary Cistern Delivery for AAV-Based Gene Therapy: A Technical Note for Nonhuman Primates.
Lluis Samaranch, John Bringas, Philip Pivirotto, Waldy San Sebastian, John Forsayeth

Hum Gene Ther Methods· February 2016

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SAFETY AND TOLERABILITY OF MRI-GUIDED INFUSION OF AAV2-hAADC INTO THE MID-BRAIN OF NON-HUMAN PRIMATE.
Waldy San Sebastian, Adrian P Kells, John Bringas, Lluis Samaranch, Piotr Hadaczek

Mol Ther Methods Clin Dev· October 2014

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Translational fidelity of intrathecal delivery of self-complementary AAV9-survival motor neuron 1 for spinal muscular atrophy.
Marco A Passini, Jie Bu, Amy M Richards, Christopher M Treleaven, Jennifer A Sullivan, Lluis Samaranch

Hum Gene Ther· July 2014

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Distribution of nanoparticles throughout the cerebral cortex of rodents and non-human primates: Implications for gene and drug therapy.
Ernesto A Salegio, Hillary Streeter, Nikhil Dube, Piotr Hadaczek, Lluis Samaranch

Front Neuroanat· March 2014

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AAV9-mediated expression of a non-self protein in nonhuman primate central nervous system triggers widespread neuroinflammation driven by antigen-presenting cell transduction.
Lluis Samaranch, Waldy San Sebastian, Adrian P Kells, Ernesto A Salegio, Gregory Heller

Mol Ther· February 2014

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Gene therapy for misfolding protein diseases of the central nervous system.
Waldy San Sebastian, Lluis Samaranch, Adrian P Kells, John Forsayeth, Krystof S Bankiewicz

Neurotherapeutics· July 2013

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Strong cortical and spinal cord transduction after AAV7 and AAV9 delivery into the cerebrospinal fluid of nonhuman primates.
Lluis Samaranch, Ernesto A Salegio, Waldy San Sebastian, Adrian P Kells, John R Bringas

Hum Gene Ther· May 2013

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H1-MAPT and the risk for familial essential tremor.
Elena García-Martín, Carmen Martínez, Hortensia Alonso-Navarro, Julián Benito-León, Oswaldo Lorenzo-Betancor, Lluis Samaranch

PLoS One· February 2013

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Age at onset in LRRK2-associated PD is modified by SNCA variants.
Teresa Botta-Orfila, Mario Ezquerra, Pau Pastor, Rubén Fernández-Santiago, Claustre Pont-Sunyer, Lluis Samaranch

J Mol Neurosci· September 2012

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