Publications by authors named "Logine Negm"

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Patterns of hypermutation shape tumorigenesis and immunotherapy response in mismatch-repair-deficient glioma.
Nicholas R Fernandez, Yuan Chang, Nuno M Nunes, Jose R Dimayacyac, Adrian Levine, Logine Negm

Nat Genet· December 2025

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A population-based analysis of the molecular landscape of glioma in adolescents and young adults reveals insights into gliomagenesis.
Julie Bennett, Adrian B Levine, Liana Nobre, Logine Negm, Jiil Chung

Nat Cancer· June 2025

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The landscape of primary mismatch repair deficient gliomas in children, adolescents, and young adults: a multi-cohort study.
Logine Negm, Jiil Chung, Liana Nobre, Julie Bennett, Nicholas R Fernandez

Lancet Oncol· January 2025

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A Validated Highly Sensitive Microsatellite Instability Assay Accurately Identifies Individuals Harboring Biallelic Germline PMS2 Pathogenic Variants in Constitutional Mismatch Repair Deficiency.
Fátima Marín, Júlia Canet-Hermida, Vanessa Bianchi, Jiil Chung, Katharina Wimmer, Logine Negm

Clin Chem· May 2024

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Clinical and biological landscape of constitutional mismatch-repair deficiency syndrome: an International Replication Repair Deficiency Consortium cohort study.
Ayse Bahar Ercan, Melyssa Aronson, Nicholas R Fernandez, Yuan Chang, Adrian Levine, Logine Negm

Lancet Oncol· May 2024

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Precision immuno-oncology approach for four malignant tumors in siblings with constitutional mismatch repair deficiency syndrome.
Hana Palova, Anirban Das, Petra Pokorna, Viera Bajciova, Zdenek Pavelka, Logine Negm

NPJ Precis Oncol· May 2024

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Combined Immunotherapy Improves Outcome for Replication-Repair-Deficient (RRD) High-Grade Glioma Failing Anti-PD-1 Monotherapy: A Report from the International RRD Consortium.
Anirban Das, Nicholas R Fernandez, Adrian Levine, Vanessa Bianchi, Lucie K Stengs, Logine Negm

Cancer Discov· February 2024

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Efficacy of Nivolumab in Pediatric Cancers with High Mutation Burden and Mismatch Repair Deficiency.
Anirban Das, Uri Tabori, Lauren C Sambira Nahum, Natalie B Collins, Rebecca Deyell, Logine Negm

Clin Cancer Res· December 2023

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Using comprehensive genomic and functional analyses for resolving genotype-phenotype mismatches in children with suspected CMMRD in Lebanon: an IRRDC study.
Dima Hamideh, Anirban Das, Vanessa Bianchi, Jiil Chung, Logine Negm

Hum Genet· April 2023

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Genomic Microsatellite Signatures Identify Germline Mismatch Repair Deficiency and Risk of Cancer Onset.
Jiil Chung, Logine Negm, Vanessa Bianchi, Lucie Stengs, Anirban Das

J Clin Oncol· February 2023

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Recurrent posterior fossa group A (PFA) ependymoma in a young child with constitutional mismatch repair deficiency (CMMRD).
Mayen Briggs, Anirban Das, Helen Firth, Adrian Levine, Santiago Sánchez-Ramírez, Logine Negm

Neuropathol Appl Neurobiol· February 2023

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Somatostatin slows Aβ plaque deposition in aged APP mice by blocking Aβ aggregation.
Declan Williams, Bei Qi Yan, Hansen Wang, Logine Negm, Christopher Sackmann

Sci Rep· February 2023

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Immune Checkpoint Inhibition as Single Therapy for Synchronous Cancers Exhibiting Hypermutation: An IRRDC Study.
Jacob J Henderson, Anirban Das, Daniel A Morgenstern, Sumedha Sudhaman, Vanessa Bianchi, Logine Negm

JCO Precis Oncol· March 2022

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Upfront Adjuvant Immunotherapy of Replication Repair-Deficient Pediatric Glioblastoma With Chemoradiation-Sparing Approach.
Trisha Larkin, Anirban Das, Vanessa Bianchi, Sumedha Sudhaman, Jiil Chung, Logine Negm

JCO Precis Oncol· November 2021

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