Publications by authors named "Loic Vincent"

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Erratum to: Aflibercept, a New Way to Target Angiogenesis in the Second Line Treatment of Metastatic Colorectal Cancer (mCRC).
Mario Scartozzi, Loic Vincent, Marielle Chiron, Stefano Cascinu

Target Oncol· February 2017

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Aflibercept, a New Way to Target Angiogenesis in the Second Line Treatment of Metastatic Colorectal Cancer (mCRC).
Mario Scartozzi, Loic Vincent, Marielle Chiron, Stefano Cascinu

Target Oncol· August 2016

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Concomitant Inhibition of PI3Kβ and BRAF or MEK in PTEN-Deficient/BRAF-Mutant Melanoma Treatment: Preclinical Assessment of SAR260301 Oral PI3Kβ-Selective Inhibitor.
Hélène Bonnevaux, Olivier Lemaitre, Loic Vincent, Mikhail N Levit, Fanny Windenberger

Mol Cancer Ther· July 2016

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Differential antitumor activity of aflibercept and bevacizumab in patient-derived xenograft models of colorectal cancer.
Marielle Chiron, Rebecca G Bagley, Jack Pollard, Parminder K Mankoo, Christophe Henry, Loïc Vincent

Mol Cancer Ther· June 2014

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Preparation and optimization of new 4-(2-(indolin-1-yl)-2-oxoethyl)-2-morpholinothiazole-5-carboxylic acid and amide derivatives as potent and selective PI3Kβ inhibitors.
Victor Certal, Frank Halley, Angela Virone-Oddos, Bruno Filoche-Rommé, Jean-Christophe Carry, Loic Vincent

Bioorg Med Chem Lett· March 2014

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Discovery and optimization of pyrimidone indoline amide PI3Kβ inhibitors for the treatment of phosphatase and tensin homologue (PTEN)-deficient cancers.
Victor Certal, Jean-Christophe Carry, Frank Halley, Angela Virone-Oddos, Fabienne Thompson, Loïc Vincent

J Med Chem· February 2014

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Preparation and optimization of new 4-(morpholin-4-yl)-(6-oxo-1,6-dihydropyrimidin-2-yl)amide derivatives as PI3Kβ inhibitors.
Victor Certal, Frank Halley, Angela Virone-Oddos, Fabienne Thompson, Bruno Filoche-Rommé, Loic Vincent

Bioorg Med Chem Lett· October 2012

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Discovery and optimization of new benzimidazole- and benzoxazole-pyrimidone selective PI3Kβ inhibitors for the treatment of phosphatase and TENsin homologue (PTEN)-deficient cancers.
Victor Certal, Frank Halley, Angela Virone-Oddos, Cécile Delorme, Andreas Karlsson, Loic Vincent

J Med Chem· May 2012

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Long-lasting enfuvirtide carrier pentasaccharide conjugates with potent anti-human immunodeficiency virus type 1 activity.
Thierry Huet, Olivier Kerbarh, Dominique Schols, Pascal Clayette, Cécile Gauchet, Loïc Vincent

Antimicrob Agents Chemother· January 2010

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The microtubule-targeting agent CA4P regresses leukemic xenografts by disrupting interaction with vascular cells and mitochondrial-dependent cell death.
Isabelle Petit, Matthias A Karajannis, Loic Vincent, Lauren Young, Jason Butler

Blood· February 2008

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In vivo-restricted and reversible malignancy induced by human herpesvirus-8 KSHV: a cell and animal model of virally induced Kaposi's sarcoma.
Agata D'Agostino Mutlu, Lucas E Cavallin, Loïc Vincent, Chiara Chiozzini, Pilar Eroles

Cancer Cell· March 2007

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VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche.
Rosandra N Kaplan, Rebecca D Riba, Stergios Zacharoulis, Anna H Bramley, Loïc Vincent

Nature· December 2005

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Combretastatin A4 phosphate induces rapid regression of tumor neovessels and growth through interference with vascular endothelial-cadherin signaling.
Loïc Vincent, Pouneh Kermani, Lauren M Young, Joseph Cheng, Fan Zhang, Heidi Bompais-Vincent

J Clin Invest· November 2005

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Simulated microgravity impairs leukemic cell survival through altering VEGFR-2/VEGF-A signaling pathway.
Loïc Vincent, Patricia Avancena, Joseph Cheng, Shahin Rafii, Sina Y Rabbany

Ann Biomed Eng· October 2005

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Adenovirus vector E4 gene regulates connexin 40 and 43 expression in endothelial cells via PKA and PI3K signal pathways.
Fan Zhang, Joseph Cheng, George Lam, David K Jin, Loïc Vincent

Circ Res· May 2005

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Fetal stromal-dependent paracrine and intracrine vascular endothelial growth factor-a/vascular endothelial growth factor receptor-1 signaling promotes proliferation and motility of human primary myeloma cells.
Loïc Vincent, David K Jin, Matthias A Karajannis, Koji Shido, Andrea T Hooper

Cancer Res· April 2005

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Neurotrophins promote revascularization by local recruitment of TrkB+ endothelial cells and systemic mobilization of hematopoietic progenitors.
Pouneh Kermani, Dahlia Rafii, David K Jin, Paul Whitlock, Wendy Schaffer, Loic Vincent

J Clin Invest· March 2005

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Elastin-derived peptides enhance angiogenesis by promoting endothelial cell migration and tubulogenesis through upregulation of MT1-MMP.
Arnaud Robinet, Abdel Fahem, Jean-Hubert Cauchard, Eric Huet, Loïc Vincent

J Cell Sci· January 2005

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Dose-dependent effect of dehydroepiandrosterone, but not of its sulphate ester, on angiogenesis.
Julia Varet, Loïc Vincent, Yvette Akwa, Pezhman Mirshahi, Agnès Lahary

Eur J Pharmacol· October 2004

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Vascular frontiers without borders: multifaceted roles of platelet-derived growth factor (PDGF) in supporting postnatal angiogenesis and lymphangiogenesis.
Loïc Vincent, Shahin Rafii

Cancer Cell· October 2004

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Efficacy of dendrimer-mediated angiostatin and TIMP-2 gene delivery on inhibition of tumor growth and angiogenesis: in vitro and in vivo studies.
Loïc Vincent, Julia Varet, Jean-Yves Pille, Heidi Bompais, Paule Opolon

Int J Cancer· June 2003

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Insights in the molecular mechanisms of the anti-angiogenic effect of an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase.
Loïc Vincent, Patricia Albanese, Heidi Bompais, Georges Uzan, Jean Pierre Vannier

Thromb Haemost· March 2003

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Cerivastatin, an inhibitor of 3-hydroxy-3-methylglutaryl coenzyme a reductase, inhibits endothelial cell proliferation induced by angiogenic factors in vitro and angiogenesis in in vivo models.
Loïc Vincent, Claudine Soria, Farrokh Mirshahi, Paule Opolon, Zohair Mishal

Arterioscler Thromb Vasc Biol· April 2002

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