Publications by authors named "Lon Smith"

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A Phase I Dose-Escalation and Dose-Expansion Study of FCN-437c, a Novel CDK4/6 Inhibitor, in Patients with Advanced Solid Tumors.
Amita Patnaik, Erika Hamilton, Yan Xing, Drew W Rasco, Lon Smith

Cancers (Basel)· October 2022

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A First-in-Human Phase I Study of OPB-111077, a Small-Molecule STAT3 and Oxidative Phosphorylation Inhibitor, in Patients with Advanced Cancers.
Anthony Tolcher, Keith Flaherty, Geoffrey I Shapiro, Jordan Berlin, Thomas Witzig, Lon Smith

Oncologist· June 2018

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Phase I Study of Pembrolizumab (MK-3475; Anti-PD-1 Monoclonal Antibody) in Patients with Advanced Solid Tumors.
Amita Patnaik, S Peter Kang, Drew Rasco, Kyriakos P Papadopoulos, Jeroen Elassaiss-Schaap, Lon Smith

Clin Cancer Res· October 2015

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Pharmacogenomic diversity of tamoxifen metabolites and estrogen receptor genes in Hispanics and non-Hispanic whites with breast cancer.
Leticia B A Rangel, Jodi L Taraba, Christopher R Frei, Lon Smith, Gladys Rodriguez

Breast Cancer Res Treat· December 2014

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Phase I first-in-human study of CUDC-101, a multitargeted inhibitor of HDACs, EGFR, and HER2 in patients with advanced solid tumors.
Toshio Shimizu, Patricia M LoRusso, Kyri P Papadopoulos, Amita Patnaik, Muralidhar Beeram, Lon S Smith

Clin Cancer Res· October 2014

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A phase 1b study of trametinib, an oral Mitogen-activated protein kinase kinase (MEK) inhibitor, in combination with gemcitabine in advanced solid tumours.
Jeffrey R Infante, Kyriakos P Papadopoulos, Johanna C Bendell, Amita Patnaik, Howard A Burris, Lon Smith

Eur J Cancer· June 2013

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The clinical effect of the dual-targeting strategy involving PI3K/AKT/mTOR and RAS/MEK/ERK pathways in patients with advanced cancer.
Toshio Shimizu, Anthony W Tolcher, Kyriakos P Papadopoulos, Muralidhar Beeram, Drew W Rasco, Lon S Smith

Clin Cancer Res· April 2012

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Gemcitabine plus nab-paclitaxel is an active regimen in patients with advanced pancreatic cancer: a phase I/II trial.
Daniel D Von Hoff, Ramesh K Ramanathan, Mitesh J Borad, Daniel A Laheru, Lon S Smith

J Clin Oncol· December 2011

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Cantuzumab mertansine in a three-times a week schedule: a phase I and pharmacokinetic study.
Jordi Rodon, Mitchell Garrison, Lisa A Hammond, Johann de Bono, Lon Smith

Cancer Chemother Pharmacol· October 2008

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Platelet-derived growth factor receptor inhibition and chemotherapy for castration-resistant prostate cancer with bone metastases.
Paul Mathew, Peter F Thall, Corazon D Bucana, William K Oh, Michael J Morris, Lon Smith

Clin Cancer Res· October 2007

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A randomized phase I and pharmacological trial of sequences of 1,3-bis(2-chloroethyl)-1-nitrosourea and temozolomide in patients with advanced solid neoplasms.
Lisa A Hammond, John R Eckardt, John G Kuhn, Stanton L Gerson, Tom Johnson, Lon Smith

Clin Cancer Res· March 2004

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Cantuzumab mertansine, a maytansinoid immunoconjugate directed to the CanAg antigen: a phase I, pharmacokinetic, and biologic correlative study.
Anthony W Tolcher, Leonel Ochoa, Lisa A Hammond, Amita Patnaik, Tam Edwards, Lon Smith

J Clin Oncol· January 2003

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