Publications by authors named "Lonnie Shea"

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Limitations in PPARα-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells.
Anne C Lietzke, Emily M Walker, Elizabeth Bealer, Kelly Crumley, Jessica King, Lonnie D Shea

Nat Commun· December 2025

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Gamma Irradiation of Poly(lactide-co-glycolide) Scaffolds Reduces the Mechanical Stability and Function of Islet Grafts in Diabetic Nonhuman Primates.
Jessica L King, Christopher Spencer, Richard Youngblood, Kelly Crumley, Elizabeth Bealer, Lonnie D Shea

Biotechnol Bioeng· December 2025

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Pre-Culture of Scaffolds with Vasculogenic Cells Improves Stem Cell-Derived β Cell Transplantation.
Kelly M Crumley, Elizabeth J Bealer, Nicholas G Schott, Jan P Stegemann, Lonnie D Shea

Tissue Eng Part A· November 2025

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Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles.
Jeffrey A Ma, Sophia M Orbach, Kate V Griffin, Kathryn Kang, Yining Zhang, Lonnie D Shea

Mol Oncol· October 2025

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Exendin-4 enhances insulin-positive phenotype of human pluripotent stem cell-derived β cells during transplantation.
Kelly M Crumley, Elizabeth J Bealer, Anne C Lietzke, Scott A Soleimanpour, Lonnie D Shea

Mol Ther· October 2025

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Nanoparticle and epothilone D combinatorial intervention improves motor performance and regeneration in chronic cervical spinal cord injury.
Sarah E Hocevar, Brian C Ross, Samantha R Schwartz, Brooke M Smiley, Brian J Cummings, Lonnie D Shea

Neurotherapeutics· October 2025

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Limitations in PPAR⍺-dependent mitochondrial programming restrain the differentiation of human stem cell-derived β cells.
Anne C Lietzke, Emily M Walker, Elizabeth Bealer, Kelly Crumley, Jessica King, Lonnie D Shea

bioRxiv· August 2025

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Early nanoparticle intervention preserves motor function following cervical spinal cord injury.
Sarah E Hocevar, Brian C Ross, Yinghao Wang, Cecelia R Crowther, Samantha R Schwartz, Lonnie D Shea

Bioeng Transl Med· July 2025

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Engineering immunity using metabolically active polymeric nanoparticles.
Kate V Griffin, Michael N Saunders, Costas A Lyssiotis, Lonnie D Shea

Trends Biotechnol· June 2025

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Anti-TNF-α antisense-oligonucleotide-conjugated PLG nanoparticles protect transplanted islets.
Elizabeth J Bealer, Namit Padgaonkar, Kelly Crumley, Eiji Saito, Zoe Beekman, Lonnie D Shea

Mol Ther Methods Clin Dev· June 2025

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Design Principles of an Engineered Metastatic Niche for Monitoring of Cancer Progression.
Guillermo Escalona, Ramon Ocadiz-Ruiz, Jeffrey A Ma, Ian A Schrack, Brian C Ross, Lonnie D Shea

Biotechnol Bioeng· March 2025

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Allergen-Encapsulating Nanoparticles Reprogram Pathogenic Allergen-Specific Th2 Cells to Suppress Food Allergy.
Michael N Saunders, Laila M Rad, Laura A Williams, Jeffrey J Landers, Russell R Urie, Lonnie D Shea

Adv Healthc Mater· February 2025

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Engineered immunological niche directs therapeutic development in models of progressive multiple sclerosis.
Laila M Rad, Kevin R Hughes, Sydney N Wheeler, Joseph T Decker, Sophia M Orbach, Lonnie D Shea

Proc Natl Acad Sci U S A· February 2025

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Detecting metastatic potential of cancer through longitudinal vasculature imaging of biomaterial scaffold using non-invasive photoacoustic microscopy and optical coherence tomography.
Zhanpeng Xu, Guillermo Escalona, Ian Schrack, Wei Zhang, Tianqu Zhai, Lonnie D Shea

Theranostics· January 2025

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Longitudinal Monitoring of T cell Dynamics in Metastatic Breast Cancer via a Remote Diagnostic Implant.
Ian A Schrack, Rebecca S Pereles, Brian C Ross, Jeffrey A Ma, Russell R Urie, Lonnie D Shea

Immunomedicine· December 2024

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Polymer scaffolds delineate healthy from diseased states at sites distal from the pancreas in two models of type 1 diabetes.
Jessica L King, Russell R Urie, Aaron H Morris, Laila Rad, Elizabeth Bealer, Lonnie D Shea

Biotechnol Bioeng· November 2024

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Immunotherapy with biodegradable nanoparticles encapsulating the oligosaccharide galactose-alpha-1,3-galactose enhance immune tolerance against alpha-gal sensitization in a murine model of alpha-gal syndrome.
Michael N Saunders, Claudia M Rival, Mahua Mandal, Kayla Cramton, Laila M Rad, Lonnie D Shea

Front Allergy· August 2024

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Dynamic Transcriptional Programs During Single NK Cell Killing: Connecting Form to Function in Cellular Immunotherapy.
Joseph T Decker, Matthew S Hall, Devak Nanua, Sophia M Orbach, Jyotirmoy Roy, Lonnie D Shea

Cell Mol Bioeng· June 2024

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Engineered Immunologic Niche Monitors Checkpoint Blockade Response and Probes Mechanisms of Resistance.
Ravi M Raghani, Russell R Urie, Jeffrey A Ma, Guillermo Escalona, Ian A Schrack, Lonnie D Shea

Immunomedicine· June 2024

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Biomarkers from subcutaneous engineered tissues predict acute rejection of organ allografts.
Russell R Urie, Aaron Morris, Diana Farris, Elizabeth Hughes, Chengchuan Xiao, Lonnie D Shea

Sci Adv· May 2024

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Engineering nanoparticle therapeutics for food allergy.
Laila M Rad, Gabriel Arellano, Joseph R Podojil, Jessica J O'Konek, Lonnie D Shea

J Allergy Clin Immunol· March 2024

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Multichannel bridges and NSC synergize to enhance axon regeneration, myelination, synaptic reconnection, and recovery after SCI.
Usha Nekanti, Pooja S Sakthivel, Atena Zahedi, Dana A Creasman, Rebecca A Nishi, Lonnie D Shea

NPJ Regen Med· March 2024

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Human Breast Cancer Cell Lines Differentially Modulate Signaling from Distant Microenvironments, Which Reflects Their Metastatic Potential.
Ramon Ocadiz-Ruiz, Joseph T Decker, Kate Griffin, Zoey M Tan, Nishant K Domala, Lonnie D Shea

Cancers (Basel)· February 2024

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Grand Challenges at the Interface of Engineering and Medicine.
Shankar Subramaniam, Metin Akay, Mark A Anastasio, Vasudev Bailey, David Boas, Lonnie D Shea

IEEE Open J Eng Med Biol· February 2024

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An engineered niche delineates metastatic potential of breast cancer.
Sophia M Orbach, Christian Y DeVaull, Elizabeth J Bealer, Brian C Ross, Jacqueline S Jeruss, Lonnie D Shea

Bioeng Transl Med· January 2024

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