Publications by authors named "Lora Tucker"

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A "Prozone-Like" Effect Influences the Efficacy of the Monoclonal Antibody ABT-700 against the Hepatocyte Growth Factor Receptor.
Kedar S Vaidya, Anatol Oleksijew, Lora A Tucker, William N Pappano, Mark G Anderson

Pharmacology· July 2018

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ABBV-399, a c-Met Antibody-Drug Conjugate that Targets Both -Amplified and c-Met-Overexpressing Tumors, Irrespective of Pathway Dependence.
Jieyi Wang, Mark G Anderson, Anatol Oleksijew, Kedar S Vaidya, Erwin R Boghaert, Lora Tucker

Clin Cancer Res· February 2017

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Anti-c-Met monoclonal antibody ABT-700 breaks oncogene addiction in tumors with MET amplification.
Jieyi Wang, Liliane Goetsch, Lora Tucker, Qian Zhang, Alexandra Gonzalez

BMC Cancer· February 2016

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Genetic inhibition of the atypical kinase Wee1 selectively drives apoptosis of p53 inactive tumor cells.
William N Pappano, Qian Zhang, Lora A Tucker, Chris Tse, Jieyi Wang

BMC Cancer· June 2014

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Substituted 4-amino-1H-pyrazolo[3,4-d]pyrimidines as multi-targeted inhibitors of insulin-like growth factor-1 receptor (IGF1R) and members of ErbB-family receptor kinases.
Gary T Wang, Robert A Mantei, Robert D Hubbard, Julie L Wilsbacher, Qian Zhang, Lora Tucker

Bioorg Med Chem Lett· October 2010

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Imidazo[2,1-b]thiazoles: multitargeted inhibitors of both the insulin-like growth factor receptor and members of the epidermal growth factor family of receptor tyrosine kinases.
Steve D Fidanze, Scott A Erickson, Gary T Wang, Robert Mantei, Richard F Clark, Lora A Tucker

Bioorg Med Chem Lett· April 2010

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Reducing agent-mediated precipitation of high-abundance plasma proteins.
Scott E Warder, Lora A Tucker, Tamara J Strelitzer, Evelyn M McKeegan, Joseph L Meuth

Anal Biochem· April 2009

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Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases.
Robert D Hubbard, Nwe Y Bamaung, Steve D Fidanze, Scott A Erickson, Fabio Palazzo, Lora A Tucker

Bioorg Med Chem Lett· March 2009

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Discovery, identification, and characterization of candidate pharmacodynamic markers of methionine aminopeptidase-2 inhibition.
Scott E Warder, Lora A Tucker, Shaun M McLoughlin, Tamara J Strelitzer, Joseph L Meuth

J Proteome Res· November 2008

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Insulin-like growth factor-1 receptor and ErbB kinase inhibitor combinations block proliferation and induce apoptosis through cyclin D1 reduction and Bax activation.
Julie L Wilsbacher, Qian Zhang, Lora A Tucker, Robert D Hubbard, George S Sheppard

J Biol Chem· August 2008

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Correlation of tumor growth suppression and methionine aminopetidase-2 activity blockade using an orally active inhibitor.
Jieyi Wang, Lora A Tucker, Jason Stavropoulos, Qian Zhang, Yi-Chun Wang

Proc Natl Acad Sci U S A· February 2008

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Identification of Ras-related nuclear protein, targeting protein for xenopus kinesin-like protein 2, and stearoyl-CoA desaturase 1 as promising cancer targets from an RNAi-based screen.
Susan E Morgan-Lappe, Lora A Tucker, Xiaoli Huang, Qian Zhang, Aparna V Sarthy

Cancer Res· May 2007

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