Publications by authors named "Loren Denlinger"

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High airway TSLP in asthma associates with type 2 inflammation, mucus plugging and airway remodeling.
Kritika Khanna, Monica Tang, Nathan D Jackson, Mats W Johansson, Eugene R Bleecker, Loren C Denlinger

J Allergy Clin Immunol· December 2025

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Proteomic Analysis of Asthma Airway Inflammation after Allergen Challenge: A Heterogeneous Response.
Mats W Johansson, Stephane Esnault, Robert J Millikin, John W Steill, Kristine E Lee, Loren C Denlinger

Am J Respir Crit Care Med· August 2025

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α-Antitrypsin Gene Variation Associates With Asthma Exacerbations and Related Health Care Utilization.
Victor E Ortega, Vickram Tejwani, Abhishek Kumar Shrivastav, Sara Pasha, Joe G Zein, Loren Denlinger

J Allergy Clin Immunol Pract· July 2025

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Clinical and Biological Features of a Thickened Basement Membrane Zone in Asthma.
Clarus Leung, Monica Tang, Walter E Finkbeiner, Mats W Johansson, Loren C Denlinger

Am J Respir Crit Care Med· May 2025

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Mitochondrial DNA copy number variation in asthma risk, severity, and exacerbations.
Weiling Xu, Yun Soo Hong, Bo Hu, Suzy A A Comhair, Allison J Janocha, Loren C Denlinger

J Allergy Clin Immunol· April 2025

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Type 1 Immune Responses Related to Viral Infection Influence Corticosteroid Response in Asthma.
John V Fahy, Nathan D Jackson, Satria P Sajuthi, Elmar Pruesse, Camille M Moore, Loren Denlinger

Am J Respir Crit Care Med· February 2025

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A method for MRI-guided bronchoscopy to identify obstructed airway segments.
David G Mummy, Marrissa J McIntosh, Katherine J Carey, Shannon Kehoe, Stephane Esnault, Loren C Denlinger

Physiol Rep· February 2025

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Development of an asthma health-care burden score as a measure of severity and predictor of remission in SARP III and U-BIOPRED: results from two major longitudinal asthma cohorts.
Joe G Zein, Nazanin Zounemat-Kerman, Ian M Adcock, Bo Hu, Amy Attaway, Loren C Denlinger

Lancet Respir Med· January 2025

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Serum cAMP levels are increased in patients with asthma.
Steven S An, Gaoyuan Cao, Kwangmi Ahn, Jordan Lee, Dae Young Jung, Loren Denlinger

J Clin Invest· January 2025

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Eosinophil-Epithelial Cell Interactions in Asthma.
Breanne N Steffan, Elizabeth A Townsend, Loren C Denlinger, Mats W Johansson

Int Arch Allergy Immunol· November 2024

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Utility of eosinophil peroxidase as a biomarker of eosinophilic inflammation in asthma.
Monica Tang, Annabelle R Charbit, Mats W Johansson, Nizar N Jarjour, Loren C Denlinger

J Allergy Clin Immunol· September 2024

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Comparison of Asthma Phenotypes in Severe Asthma Cohorts (SARP, U-BIOPRED, ProAR and COREA) From 4 Continents.
So-Young Park, Stephen Fowler, Dominic E Shaw, Ian M Adcock, Ana R Sousa, Loren Denlinger

Allergy Asthma Immunol Res· July 2024

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A Novel Air Trapping Segment Score Identifies Opposing Effects of Obesity and Eosinophilia on Air Trapping in Asthma.
Clarus Leung, Monica Tang, Brendan K Huang, Sean B Fain, Eric A Hoffman, Loren C Denlinger

Am J Respir Crit Care Med· May 2024

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A common polymorphism in the Intelectin-1 gene influences mucus plugging in severe asthma.
Jamie L Everman, Satria P Sajuthi, Maude A Liegeois, Nathan D Jackson, Erik H Collet, Loren C Denlinger

Nat Commun· May 2024

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Protein-Protein interactive networks identified in bronchoalveolar lavage of severe compared to nonsevere asthma.
Annette T Hastie, Andrew C Bishop, Mohammad S Khan, Eugene R Bleecker, Mario Castro, Loren C Denlinger

Clin Exp Allergy· April 2024

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Persistent mucus plugs in proximal airways are consequential for airflow limitation in asthma.
Brendan K Huang, Brett M Elicker, Travis S Henry, Kimberly G Kallianos, Lewis D Hahn, Loren C Denlinger

JCI Insight· February 2024

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Mitochondrial DNA Copy Number Variation in Asthma Risk, Severity, and Exacerbations.
Weiling Xu, Yun Soo Hong, Bo Hu, Suzy A A Comhair, Allison J Janocha, Loren C Denlinger

medRxiv· December 2023

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Development and Dynamic Responsiveness of the Acute Asthma Exacerbation Survey in Patients With Moderate to Severe Disease.
Scott A Laurenzo, Elizabeth A Townsend, Nicole M Lane Starr, Lori J Wollet, Mario Castro, Loren C Denlinger

J Allergy Clin Immunol Pract· November 2023

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Investigations of a combination of atopic status and age of asthma onset identify asthma subphenotypes.
Huashi Li, Mario Castro, Loren C Denlinger, Serpil C Erzurum, John V Fahy

J Asthma· October 2023

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Genetic analyses of chr11p15.5 region identify - associated with asthma-related phenotypes.
Xingnan Li, Huashi Li, Stephanie A Christenson, Mario Castro, Loren C Denlinger

J Asthma· October 2023

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P2X signaling influences the production of pro-resolving and pro-inflammatory lipid mediators in alveolar macrophages derived from individuals with asthma.
Elizabeth A Townsend, Arturo Guadarrama, Lei Shi, Elon Roti Roti, Loren C Denlinger

Am J Physiol Lung Cell Mol Physiol· October 2023

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Comparison of hyperpolarized He-MRI, CT based parametric response mapping, and mucus scores in asthmatics.
Katherine J Carey, Peter Hotvedt, David G Mummy, Kristine E Lee, Loren C Denlinger

Front Physiol· August 2023

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Imaging Regional Airway Involvement of Asthma: Heterogeneity in Ventilation, Mucus Plugs and Remodeling.
Mark L Schiebler, Nanae Tsuchiya, Andrew Hahn, Sean Fain, Loren Denlinger

Adv Exp Med Biol· July 2023

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Clinical Trial Design Innovations for Precision Medicine in Asthma.
Salman Siddiqui, Elin Haf Davies, Majid Afshar, Loren C Denlinger

Adv Exp Med Biol· July 2023

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Bronchial epithelial cell transcriptional responses to inhaled corticosteroids dictate severe asthmatic outcomes.
Scott P Ginebaugh, Matthias Hagner, Anuradha Ray, Serpil C Erzurum, Suzy A A Comhair, Loren C Denlinger

J Allergy Clin Immunol· June 2023

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