Publications by authors named "Loren Runnels"

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The cytoplasmic domains of the CNNM family of transmembrane proteins modulate the ion channel-kinase TRPM7.
Sandra Tetteh, Pengyu Zong, Jianlin Feng, Emma L Lee, Namariq Al-Saadi, Loren W Runnels

J Biol Chem· November 2025

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TRPM7 channel activity promotes the pathogenesis of abdominal aortic aneurysms.
Pengyu Zong, Cindy X Li, Jianlin Feng, Zhichao Yue, Thushara Nethramangalath, Loren W Runnels

Nat Cardiovasc Res· February 2025

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AI decodes CNNM Na/Mg exchange.
Thushara Nethramangalath, Loren W Runnels

Structure· January 2025

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Structural insights into regulation of CNNM-TRPM7 divalent cation uptake by the small GTPase ARL15.
Luba Mahbub, Guennadi Kozlov, Pengyu Zong, Emma L Lee, Sandra Tetteh, Loren Runnels

Elife· July 2023

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Structural insights into regulation of TRPM7 divalent cation uptake by the small GTPase ARL15.
Luba Mahbub, Guennadi Kozlov, Pengyu Zong, Sandra Tetteh, Thushara Nethramangalath, Loren W Runnels

bioRxiv· January 2023

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Impact of Zinc Transport Mechanisms on Embryonic and Brain Development.
Jeremy Willekens, Loren W Runnels

Nutrients· June 2022

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CNNM proteins selectively bind to the TRPM7 channel to stimulate divalent cation entry into cells.
Zhiyong Bai, Jianlin Feng, Gijs A C Franken, Namariq Al'Saadi, Na Cai, Loren W Runnels

PLoS Biol· December 2021

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TRPM6 and TRPM7: Novel players in cell intercalation during vertebrate embryonic development.
Loren W Runnels, Yuko Komiya

Dev Dyn· August 2020

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Ca Signaling in Cardiac Fibroblasts and Fibrosis-Associated Heart Diseases.
Jianlin Feng, Maria K Armillei, Albert S Yu, Bruce T Liang, Loren W Runnels

J Cardiovasc Dev Dis· September 2019

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The kinase activity of the channel-kinase protein TRPM7 regulates stability and localization of the TRPM7 channel in polarized epithelial cells.
Na Cai, Liping Lou, Namariq Al-Saadi, Sandra Tetteh, Loren W Runnels

J Biol Chem· July 2018

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A Nonredundant Role for the TRPM6 Channel in Neural Tube Closure.
Yuko Komiya, Zhiyong Bai, Na Cai, Liping Lou, Namariq Al-Saadi, Loren W Runnels

Sci Rep· November 2017

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Mass Spectrometric Analysis of TRPM6 and TRPM7 Phosphorylation Reveals Regulatory Mechanisms of the Channel-Kinases.
Na Cai, Zhiyong Bai, Vikas Nanda, Loren W Runnels

Sci Rep· February 2017

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TRPM channels and magnesium in early embryonic development.
Yuko Komiya, Loren W Runnels

Int J Dev Biol· October 2016

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Hepatocystin is Essential for TRPM7 Function During Early Embryogenesis.
Jeffrey D Overton, Yuko Komiya, Courtney Mezzacappa, Kaushik Nama, Na Cai, Loren W Runnels

Sci Rep· December 2015

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Magnesium and embryonic development.
Yuko Komiya, Li-Ting Su, Hsiang-Chin Chen, Raymond Habas, Loren W Runnels

Magnes Res· February 2015

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Abnormal differentiation of dopaminergic neurons in zebrafish trpm7 mutant larvae impairs development of the motor pattern.
Amanda R Decker, Matthew S McNeill, Aaron M Lambert, Jeffrey D Overton, Yu-Chia Chen, Loren W Runnels

Dev Biol· February 2014

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Phosphatidylinositol 4,5-bisphosphate (PIP(2)) controls magnesium gatekeeper TRPM6 activity.
Jia Xie, Baonan Sun, Jianyang Du, Wenzhong Yang, Hsiang-Chin Chen, Loren W Runnels

Sci Rep· September 2013

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A key role for Mg(2+) in TRPM7's control of ROS levels during cell stress.
Hsiang-Chin Chen, Li-Ting Su, Omayra González-Pagán, Jeffrey D Overton, Loren W Runnels

Biochem J· August 2012

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Interferon-β signaling contributes to Ras transformation.
Yu-Chen Tsai, Sidney Pestka, Lu-Hai Wang, Loren W Runnels, Shan Wan

PLoS One· December 2011

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MIM regulates vertebrate neural tube closure.
Wei Liu, Yuko Komiya, Courtney Mezzacappa, Deepak K Khadka, Loren Runnels

Development· May 2011

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TRPM7 regulates polarized cell movements.
Li-Ting Su, Wei Liu, Hsiang-Chin Chen, Omayra González-Pagán, Raymond Habas, Loren W Runnels

Biochem J· March 2011

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TRPM7 regulates gastrulation during vertebrate embryogenesis.
Wei Liu, Li-Ting Su, Deepak K Khadka, Courtney Mezzacappa, Yuko Komiya, Loren W Runnels

Dev Biol· February 2011

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TRPM6 and TRPM7: A Mul-TRP-PLIK-cation of channel functions.
Loren W Runnels

Curr Pharm Biotechnol· January 2011

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Identification of a novel binding partner of phospholipase cβ1: translin-associated factor X.
Omozuanvbo R Aisiku, Loren W Runnels, Suzanne Scarlata

PLoS One· November 2010

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Blockade of TRPM7 channel activity and cell death by inhibitors of 5-lipoxygenase.
Hsiang-Chin Chen, Jia Xie, Zheng Zhang, Li-Ting Su, Lixia Yue, Loren W Runnels

PLoS One· June 2010

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