Publications by authors named "Lorena Landuzzi"

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Genomic Profiling of Highly Aggressive Musculoskeletal Sarcomas Identifies Potential Therapeutic Targets: A Single-Center Experience.
Alessandro Parra, Emanuela Palmerini, Maria Antonella Laginestra, Cristina Ferrari, Stefania Cocchi, Lorena Landuzzi

Cancers (Basel)· December 2025

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Genomic profiling of a collection of patient-derived xenografts and cell lines identified ixabepilone as an active drug against chemo-resistant osteosarcoma.
Maria Cristina Manara, Francesca Bruzzese, Laura Formentini, Lorena Landuzzi, Laura Pazzaglia

J Exp Clin Cancer Res· July 2025

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Chondrosarcoma: New Molecular Insights, Challenges in Near-Patient Preclinical Modeling, and Therapeutic Approaches.
Lorena Landuzzi, Francesca Ruzzi, Pier-Luigi Lollini, Katia Scotlandi

Int J Mol Sci· February 2025

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Lipid rafts, caveolae, and epidermal growth factor receptor family: friends or foes?
Francesca Ruzzi, Chiara Cappello, Maria Sofia Semprini, Laura Scalambra, Stefania Angelicola, Lorena Landuzzi

Cell Commun Signal· October 2024

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CD99 contributes to the EWS::FLI1 transcriptome by specifically affecting FOXM1-targets involved in the G2/M cell cycle phase, thus influencing the Ewing sarcoma genetic landscape.
Michela Pasello, Maria Antonella Laginestra, Maria Cristina Manara, Lorena Landuzzi, Francesca Ruzzi

J Cell Commun Signal· September 2024

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Engagement of CD99 Activates Distinct Programs in Ewing Sarcoma and Macrophages.
Maria Cristina Manara, Cristina Manferdini, Camilla Cristalli, Marianna Carrabotta, Spartaco Santi, Lorena Landuzzi

Cancer Immunol Res· February 2024

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IL-1 Family Members in Bone Sarcomas.
Lorena Landuzzi, Francesca Ruzzi, Evelin Pellegrini, Pier-Luigi Lollini, Katia Scotlandi

Cells· January 2024

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Innovative Breakthroughs for the Treatment of Advanced and Metastatic Synovial Sarcoma.
Lorena Landuzzi, Maria Cristina Manara, Laura Pazzaglia, Pier-Luigi Lollini, Katia Scotlandi

Cancers (Basel)· July 2023

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Synovial Sarcoma Preclinical Modeling: Integrating Transgenic Mouse Models and Patient-Derived Models for Translational Research.
Lorena Landuzzi, Francesca Ruzzi, Pier-Luigi Lollini, Katia Scotlandi

Cancers (Basel)· January 2023

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ADK-VR2, a cell line derived from a treatment-naïve patient with fusion-positive primarily crizotinib-resistant NSCLC: a novel preclinical model for new drug development of ROS1-rearranged NSCLC.
Francesca Ruzzi, Stefania Angelicola, Lorena Landuzzi, Elena Nironi, Maria Sofia Semprini

Transl Lung Cancer Res· November 2022

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CRISPR/Cas9-mediated deletion of Interleukin-30 suppresses IGF1 and CXCL5 and boosts SOCS3 reducing prostate cancer growth and mortality.
Carlo Sorrentino, Luigi D'Antonio, Stefania Livia Ciummo, Cristiano Fieni, Lorena Landuzzi

J Hematol Oncol· October 2022

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Prevention and Therapy of Metastatic HER-2 Mammary Carcinoma with a Human Candidate HER-2 Virus-like Particle Vaccine.
Francesca Ruzzi, Arianna Palladini, Stine Clemmensen, Anette Strøbæk, Nicolaas Buijs, Lorena Landuzzi

Biomedicines· October 2022

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Lamin A and the LINC complex act as potential tumor suppressors in Ewing Sarcoma.
Francesca Chiarini, Francesca Paganelli, Tommaso Balestra, Cristina Capanni, Antonietta Fazio, Lorena Landuzzi

Cell Death Dis· April 2022

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Integrated Molecular Characterization of Patient-Derived Models Reveals Therapeutic Strategies for Treating CIC-DUX4 Sarcoma.
Marianna Carrabotta, Maria Antonella Laginestra, Giorgio Durante, Caterina Mancarella, Lorena Landuzzi

Cancer Res· February 2022

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Targeting CD99 Compromises the Oncogenic Effects of the Chimera EWS-FLI1 by Inducing Reexpression of Zyxin and Inhibition of GLI1 Activity.
Tommaso Balestra, Maria Cristina Manara, Maria Antonella Laginestra, Michela Pasello, Alessandra De Feo, Lorena Landuzzi

Mol Cancer Ther· January 2022

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Evolution of HER2-positive mammary carcinoma: HER2 loss reveals claudin-low traits in cancer progression.
Veronica Giusti, Francesca Ruzzi, Lorena Landuzzi, Marianna L Ianzano, Roberta Laranga

Oncogenesis· November 2021

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HER Tyrosine Kinase Family and Rhabdomyosarcoma: Role in Onset and Targeted Therapy.
Carla De Giovanni, Lorena Landuzzi, Arianna Palladini, Giordano Nicoletti, Patrizia Nanni

Cells· July 2021

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Ewing Sarcoma PDX Models.
Didier Surdez, Lorena Landuzzi, Katia Scotlandi, Maria Cristina Manara

Methods Mol Biol· April 2021

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Patient Derived Xenografts for Genome-Driven Therapy of Osteosarcoma.
Lorena Landuzzi, Maria Cristina Manara, Pier-Luigi Lollini, Katia Scotlandi

Cells· February 2021

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Early stability and late random tumor progression of a HER2-positive primary breast cancer patient-derived xenograft.
Lorena Landuzzi, Arianna Palladini, Claudio Ceccarelli, Sofia Asioli, Giordano Nicoletti

Sci Rep· January 2021

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IFN-γ and CD38 in Hyperprogressive Cancer Development.
Stefania Angelicola, Francesca Ruzzi, Lorena Landuzzi, Laura Scalambra, Francesco Gelsomino

Cancers (Basel)· January 2021

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Circulating miR34a levels as a potential biomarker in the follow-up of Ewing sarcoma.
Marika Sciandra, Alessandra De Feo, Alessandro Parra, Lorena Landuzzi, Pier-Luigi Lollini

J Cell Commun Signal· September 2020

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ROCK2 deprivation leads to the inhibition of tumor growth and metastatic potential in osteosarcoma cells through the modulation of YAP activity.
Cinzia Zucchini, Maria Cristina Manara, Camilla Cristalli, Marianna Carrabotta, Sara Greco, Lorena Landuzzi

J Exp Clin Cancer Res· December 2019

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Bioprofiling TS/A Murine Mammary Cancer for a Functional Precision Experimental Model.
Carla De Giovanni, Giordano Nicoletti, Lorena Landuzzi, Arianna Palladini, Pier-Luigi Lollini

Cancers (Basel)· November 2019

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Bone sarcoma patient-derived xenografts are faithful and stable preclinical models for molecular and therapeutic investigations.
Patrizia Nanni, Lorena Landuzzi, Maria Cristina Manara, Alberto Righi, Giordano Nicoletti

Sci Rep· August 2019

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