Publications by authors named "Lorey Smith"

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Ubiquitous expression of an activating mutation in the Pik3ca gene reprograms glucose and lipid metabolism in mice.
Sabrina Caiazzo, Matthew J Watt, Garron T Dodd, Jacqueline Bayliss, Helen Thomas, Lorey K Smith

PLoS One· May 2025

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Sensitivity to immune checkpoint inhibitors in BRAF/MEK inhibitor refractory melanoma.
Riyaben P Patel, Lydia Rui Jia Lim, Reem Saleh, Darius Schenk, Michael K Lee, Lorey Smith

J Immunother Cancer· May 2025

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The therapeutic potential of targeting minimal residual disease in melanoma.
Riyaben P Patel, Pretashini M Somasundram, Lorey K Smith, Karen E Sheppard, Grant A McArthur

Clin Transl Med· March 2023

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Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway.
Katherine M Hannan, Priscilla Soo, Mei S Wong, Justine K Lee, Nadine Hein, Lorey K Smith

Cell Rep· November 2022

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Inhibition of pyrimidine biosynthesis targets protein translation in acute myeloid leukemia.
Joan So, Alexander C Lewis, Lorey K Smith, Kym Stanley, Rheana Franich

EMBO Mol Med· July 2022

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Pharmacologic Reduction of Mitochondrial Iron Triggers a Noncanonical BAX/BAK-Dependent Cell Death.
Sylvain Garciaz, Andrew A Guirguis, Sebastian Müller, Fiona C Brown, Yih-Chih Chan, Lorey Smith

Cancer Discov· March 2022

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Adaptive translational reprogramming of metabolism limits the response to targeted therapy in BRAF melanoma.
Lorey K Smith, Tiffany Parmenter, Margarete Kleinschmidt, Eric P Kusnadi, Jian Kang

Nat Commun· March 2022

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Enhancing Adoptive Cell Transfer with Combination BRAF-MEK and CDK4/6 Inhibitors in Melanoma.
Peter Kar Han Lau, Carleen Cullinane, Susan Jackson, Rachael Walker, Lorey K Smith

Cancers (Basel)· December 2021

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Phenotypic Consequences of Fusions beyond Drug Resistance in High-Grade Serous Ovarian Cancer.
Kathleen I Pishas, Karla J Cowley, Ahwan Pandey, Therese Hoang, Jessica A Beach, Lorey K Smith

Cancers (Basel)· November 2021

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Metabolic Plasticity in Melanoma Progression and Response to Oncogene Targeted Therapies.
Arwa Alkaraki, Grant A McArthur, Karen E Sheppard, Lorey K Smith

Cancers (Basel)· November 2021

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Melanoma brain metastases that progress on BRAF-MEK inhibitors demonstrate resistance to ipilimumab-nivolumab that is associated with the Innate PD-1 Resistance Signature (IPRES).
Peter Kar Han Lau, Breon Feran, Lorey Smith, Arian Lasocki, Ramyar Molania, Kortnye Smith

J Immunother Cancer· October 2021

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Is resistance to targeted therapy in cancer inevitable?
Lorey K Smith, Karen E Sheppard, Grant A McArthur

Cancer Cell· August 2021

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CDK4/6 Inhibition Reprograms Mitochondrial Metabolism in BRAF Melanoma via a p53 Dependent Pathway.
Nancy T Santiappillai, Shatha Abuhammad, Alison Slater, Laura Kirby, Grant A McArthur, Lorey K Smith

Cancers (Basel)· January 2021

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Genome-wide RNAi screen for genes regulating glycolytic response to vemurafenib in BRAF melanoma cells.
Lorey K Smith, Tiffany Parmenter, Cathryn M Gould, Piyush B Madhamshettiwar, Karen E Sheppard

Sci Data· October 2020

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Obesity and the Impact on Cutaneous Melanoma: Friend or Foe?
Lorey K Smith, Shaghayegh Arabi, Emily J Lelliott, Grant A McArthur, Karen E Sheppard

Cancers (Basel)· June 2020

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Regulation of PRMT5-MDM4 axis is critical in the response to CDK4/6 inhibitors in melanoma.
Shatha AbuHammad, Carleen Cullinane, Claire Martin, Zoe Bacolas, Teresa Ward, Lorey K Smith

Proc Natl Acad Sci U S A· September 2019

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A Phenotypic High-Content Screening Assay to Identify Regulators of Membrane Protein Localization.
Lorey K Smith, Daniel W Thomas, Kaylene J Simpson, Patrick O Humbert

Assay Drug Dev Technol· October 2016

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Targeting metabolic reprogramming as a potential therapeutic strategy in melanoma.
Lorey K Smith, Aparna D Rao, Grant A McArthur

Pharmacol Res· May 2016

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Dissecting the role of polarity regulators in cancer through the use of mouse models.
Nathan J Gödde, Helen B Pearson, Lorey K Smith, Patrick O Humbert

Exp Cell Res· November 2014

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Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland.
Nathan J Godde, Julie M Sheridan, Lorey K Smith, Helen B Pearson, Kara L Britt

PLoS Genet· May 2014

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Discovery and analysis of consistent active sub-networks in cancers.
Raj K Gaire, Lorey Smith, Patrick Humbert, James Bailey, Peter J Stuckey

BMC Bioinformatics· September 2013

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