Publications by authors named "Lorraine Springuel"

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The integrated stress response promotes B7H6 expression.
Akram Obiedat, Yoav Charpak-Amikam, Julie Tai-Schmiedel, Einat Seidel, Mohamed Mahameed, Lorraine Springuel

J Mol Med (Berl)· January 2020

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Overcoming Target Driven Fratricide for T Cell Therapy.
Eytan Breman, Benjamin Demoulin, Sophie Agaugué, Sebastien Mauën, Alexandre Michaux, Lorraine Springuel

Front Immunol· October 2019

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Chimeric Antigen Receptor-T Cells for Targeting Solid Tumors: Current Challenges and Existing Strategies.
Lorraine Springuel, Caroline Lonez, Bertrand Alexandre, Eric Van Cutsem, Jean-Pascal H Machiels

BioDrugs· October 2019

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Loss of mutL homolog-1 (MLH1) expression promotes acquisition of oncogenic and inhibitor-resistant point mutations in tyrosine kinases.
Lorraine Springuel, Elisabeth Losdyck, Pascale Saussoy, Béatrice Turcq, François-Xavier Mahon

Cell Mol Life Sci· December 2016

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Distinct Acute Lymphoblastic Leukemia (ALL)-associated Janus Kinase 3 (JAK3) Mutants Exhibit Different Cytokine-Receptor Requirements and JAK Inhibitor Specificities.
Elisabeth Losdyck, Tekla Hornakova, Lorraine Springuel, Sandrine Degryse, Olga Gielen

J Biol Chem· November 2015

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JAK kinase targeting in hematologic malignancies: a sinuous pathway from identification of genetic alterations towards clinical indications.
Lorraine Springuel, Jean-Christophe Renauld, Laurent Knoops

Haematologica· October 2015

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Cooperating JAK1 and JAK3 mutants increase resistance to JAK inhibitors.
Lorraine Springuel, Tekla Hornakova, Elisabeth Losdyck, Fanny Lambert, Emilie Leroy

Blood· December 2014

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Oncogenic JAK1 and JAK2-activating mutations resistant to ATP-competitive inhibitors.
Tekla Hornakova, Lorraine Springuel, Julien Devreux, Alexandra Dusa, Stefan N Constantinescu

Haematologica· June 2011

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