Publications by authors named "Lothar Germeroth"

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Miniaturized CAR knocked onto CD3ε extends TCR function with CAR specificity under control of endogenous TCR signaling cascade.
Katrin Manske, Lisa Dreßler, Simon P Fräßle, Manuel Effenberger, Claudia Tschulik, Lothar Germeroth

J Immunol Methods· March 2024

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Activation-inducible CAR expression enables precise control over engineered CAR T cell function.
Simon P Fraessle, Claudia Tschulik, Manuel Effenberger, Vlad Cletiu, Maria Gerget, Lothar Germeroth

Commun Biol· June 2023

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Next generation automated traceless cell chromatography platform for GMP-compliant cell isolation and activation.
Sabine Radisch, Mateusz P Poltorak, Michaela Wagner, Vlad Cletiu, Christian Radisch, Lothar Germeroth

Sci Rep· April 2022

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Expamers: a new technology to control T cell activation.
Mateusz P Poltorak, Patricia Graef, Claudia Tschulik, Michaela Wagner, Vlad Cletiu, Lothar Germeroth

Sci Rep· October 2020

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A minority of T cells recognizing tumor-associated antigens presented in self-HLA can provoke antitumor reactivity.
Marthe C J Roex, Lois Hageman, Sabrina A J Veld, Esther van Egmond, Conny Hoogstraten, Lothar Germeroth

Blood· July 2020

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Generation and infusion of multi-antigen-specific T cells to prevent complications early after T-cell depleted allogeneic stem cell transplantation-a phase I/II study.
Marthe C J Roex, Peter van Balen, Lothar Germeroth, Lois Hageman, Esther van Egmond

Leukemia· March 2020

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The simultaneous isolation of multiple high and low frequent T-cell populations from donor peripheral blood mononuclear cells using the major histocompatibility complex I-Streptamer isolation technology.
Marthe C J Roex, Lois Hageman, Matthias T Heemskerk, Sabrina A J Veld, Ellis van Liempt, Lothar Germeroth

Cytotherapy· April 2018

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Generation of high-avidity, WT1-reactive CD8+ cytotoxic T cell clones with anti-leukemic activity by streptamer technology.
Antje Tunger, Rebekka Wehner, Malte von Bonin, Denise Kühn, Falk Heidenreich, Lothar Germeroth

Leuk Lymphoma· May 2017

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Longitudinal analyses of leukemia-associated antigen-specific CD8 T cells in patients after allogeneic stem cell transplantation.
Elke Rücker-Braun, Cornelia S Link, Maria Schmiedgen, Antje Tunger, Petra Vizjak, Lothar Germeroth

Exp Hematol· November 2016

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Flow cytometry-based TCR-ligand Koff -rate assay for fast avidity screening of even very small antigen-specific T cell populations ex vivo.
Magdalena Nauerth, Christian Stemberger, Fabian Mohr, Bianca Weißbrich, Matthias Schiemann, Lothar Germeroth

Cytometry A· September 2016

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Antigen-specific TIL therapy for melanoma: A flexible platform for personalized cancer immunotherapy.
Sander Kelderman, Bianca Heemskerk, Lorenzo Fanchi, Daisy Philips, Mireille Toebes, Lothar Germeroth

Eur J Immunol· June 2016

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Selection of adenovirus-specific and Epstein-Barr virus-specific T cells with major histocompatibility class I streptamers under Good Manufacturing Practice (GMP)-compliant conditions.
Christine Freimüller, Julia Stemberger, Michaela Artwohl, Lothar Germeroth, Volker Witt

Cytotherapy· July 2015

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Clinical-scale isolation of 'minimally manipulated' cytomegalovirus-specific donor lymphocytes for the treatment of refractory cytomegalovirus disease.
Marcus Odendahl, G Ulrich Grigoleit, Halvard Bönig, Michael Neuenhahn, Julia Albrecht, Lothar Germeroth

Cytotherapy· September 2014

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Lowest numbers of primary CD8(+) T cells can reconstitute protective immunity upon adoptive immunotherapy.
Christian Stemberger, Patricia Graef, Marcus Odendahl, Julia Albrecht, Georg Dössinger, Lothar Germeroth

Blood· July 2014

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Novel serial positive enrichment technology enables clinical multiparameter cell sorting.
Christian Stemberger, Stefan Dreher, Claudia Tschulik, Christine Piossek, Jeannette Bet, Lothar Germeroth

PLoS One· August 2012

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Adoptive transfer and selective reconstitution of streptamer-selected cytomegalovirus-specific CD8+ T cells leads to virus clearance in patients after allogeneic peripheral blood stem cell transplantation.
Anita Schmitt, Torsten Tonn, Dirk H Busch, Götz Ulrich Grigoleit, Hermann Einsele, Lothar Germeroth

Transfusion· March 2011

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Multimer staining of cytomegalovirus phosphoprotein 65-specific T cells for diagnosis and therapeutic purposes: a comparative study.
Junxia Yao, Clemens Bechter, Markus Wiesneth, Georg Härter, Marlies Götz, Lothar Germeroth

Clin Infect Dis· May 2008

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Reversible HLA multimers (Streptamers) for the isolation of human cytotoxic T lymphocytes functionally active against tumor- and virus-derived antigens.
Julia Neudorfer, Burkhard Schmidt, Katharina M Huster, Florian Anderl, Matthias Schiemann, Lothar Germeroth

J Immunol Methods· March 2007

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Potent inhibition of angiogenesis by D,L-peptides derived from vascular endothelial growth factor receptor 2.
Christine Piossek, Karl-Heinz Thierauch, Jens Schneider-Mergener, Rudolf Volkmer-Engert, Martin F Bachmann, Lothar Germeroth

Thromb Haemost· September 2003

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