Publications by authors named "Louis De Muynck"

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Complement dysregulation in human tauopathies.
Jacqui Nimmo, Samuel Keat, Louis De Muynck, B Paul Morgan

Brain Pathol· November 2025

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In vivo validation of novel non-invasive PHP.eB AAVs as a potential therapeutic approach for alpha-synucleinopathies.
Maria Fouka, Iraklis Tsakogias, Elena-Georgia Gialinaki, Athanasios Stavropoulos, Christiane Volbracht, Louis De Muynck

Acta Neuropathol Commun· September 2025

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Characterization of APOE Christchurch carriers in 455,306 UK Biobank participants.
Karen Y He, Ekaterina A Khramtsova, Alfredo Cabrera-Socorro, Yanfei Zhang, Shuwei Li, Louis De Muynck

Mol Neurodegener· November 2023

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Protein interactors of 3-O sulfated heparan sulfates in human MCI and age-matched control cerebrospinal fluid.
Andreia Ferreira, Evy Timmerman, An Staes, Marnik Vuylsteke, Louis De Muynck

Sci Data· March 2023

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The 3-O sulfation of heparan sulfate proteoglycans contributes to the cellular internalization of tau aggregates.
Andreia Ferreira, Ines Royaux, Jian Liu, Zhangjie Wang, Guowei Su, Louis De Muynck

BMC Mol Cell Biol· December 2022

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PIKfyve activity is required for lysosomal trafficking of tau aggregates and tau seeding.
Alberto Carpinteiro Soares, Andreia Ferreira, Jonas Mariën, Charlotte Delay, Edward Lee, Louis De Muynck

J Biol Chem· August 2021

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Differentially expressed genes in Alzheimer's disease highlighting the roles of microglia genes including OLR1 and astrocyte gene CDK2AP1.
Qingqin S Li, Louis De Muynck

Brain Behav Immun Health· May 2021

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Absence of Uptake and Prion-Like Spreading of Alpha-Synuclein and Tau After Intravitreal Injection of Preformed Fibrils.
Lien Veys, Jessie Van Houcke, Jeroen Aerts, Sophie Van Pottelberge, Michel Mahieu, Louis De Muynck

Front Aging Neurosci· January 2021

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Synthesis of 3--Sulfated Disaccharide and Tetrasaccharide Standards for Compositional Analysis of Heparan Sulfate.
Vijay Manohar Dhurandhare, Vijayakanth Pagadala, Andreia Ferreira, Louis De Muynck, Jian Liu

Biochemistry· September 2020

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RNA-Sequencing Highlights Inflammation and Impaired Integrity of the Vascular Wall in Brain Arteriovenous Malformations.
Allard J Hauer, Rachel Kleinloog, Fabrizio Giuliani, Gabriël J E Rinkel, Gerard A de Kort, Louis De Muynck

Stroke· January 2020

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Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
An Verheyen, Annick Diels, Joke Reumers, Kirsten Van Hoorde, Ilse Van den Wyngaert, Louis De Muynck

Stem Cell Reports· August 2019

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Genetically Engineered iPSC-Derived FTDP-17 MAPT Neurons Display Mutation-Specific Neurodegenerative and Neurodevelopmental Phenotypes.
An Verheyen, Annick Diels, Joke Reumers, Kirsten Van Hoorde, Ilse Van den Wyngaert, Louis De Muynck

Stem Cell Reports· August 2018

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Progranulin functions as a cathepsin D chaperone to stimulate axonal outgrowth in vivo.
Sander Beel, Matthieu Moisse, Markus Damme, Louis De Muynck, Wim Robberecht

Hum Mol Genet· August 2017

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Immunologic profiles of multiple sclerosis treatments reveal shared early B cell alterations.
James Dooley, Ine Pauwels, Dean Franckaert, Ide Smets, Josselyn E Garcia-Perez, Louis De Muynck

Neurol Neuroimmunol Neuroinflamm· August 2016

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RNA Sequencing Analysis of Intracranial Aneurysm Walls Reveals Involvement of Lysosomes and Immunoglobulins in Rupture.
Rachel Kleinloog, Bon H Verweij, Pieter van der Vlies, Patrick Deelen, Morris A Swertz, Louis de Muynck

Stroke· May 2016

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Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs.
Jie Jiang, Qiang Zhu, Tania F Gendron, Shahram Saberi, Melissa McAlonis-Downes, Louis De Muynck

Neuron· May 2016

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Restoration of progranulin expression rescues cortical neuron generation in an induced pluripotent stem cell model of frontotemporal dementia.
Susanna Raitano, Laura Ordovàs, Louis De Muynck, Wenting Guo, Ira Espuny-Camacho

Stem Cell Reports· January 2015

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The neurotrophic properties of progranulin depend on the granulin E domain but do not require sortilin binding.
Louis De Muynck, Sarah Herdewyn, Sander Beel, Wendy Scheveneels, Ludo Van Den Bosch

Neurobiol Aging· November 2013

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Progranulin does not affect motor neuron degeneration in mutant SOD1 mice and rats.
Sarah Herdewyn, Louis De Muynck, Ludo Van Den Bosch, Wim Robberecht, Philip Van Damme

Neurobiol Aging· October 2013

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Cellular effects of progranulin in health and disease.
Louis De Muynck, Philip Van Damme

J Mol Neurosci· November 2011

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Microglial upregulation of progranulin as a marker of motor neuron degeneration.
Thomas Philips, Louis De Muynck, Hoai Nguyen Thi Thu, Bea Weynants, Peter Vanacker

J Neuropathol Exp Neurol· December 2010

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Progranulin is neurotrophic in vivo and protects against a mutant TDP-43 induced axonopathy.
Angela S Laird, Annelies Van Hoecke, Louis De Muynck, Mieke Timmers, Ludo Van den Bosch

PLoS One· October 2010

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