Publications by authors named "Louis DiDone"

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Antifungal Phenothiazines: Optimization, Characterization of Mechanism, and Modulation of Neuroreceptor Activity.
Marhiah C Montoya, Louis DiDone, Richard F Heier, Marvin J Meyers, Damian J Krysan

ACS Infect Dis· April 2018

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The Celecoxib Derivative AR-12 Has Broad-Spectrum Antifungal Activity In Vitro and Improves the Activity of Fluconazole in a Murine Model of Cryptococcosis.
Kristy Koselny, Julianne Green, Louis DiDone, Justin P Halterman, Annette W Fothergill

Antimicrob Agents Chemother· December 2016

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Complex Haploinsufficiency-Based Genetic Analysis of the NDR/Lats Kinase Cbk1 Provides Insight into Its Multiple Functions in Candida albicans.
Sarah Saputo, Kaitlyn L Norman, Thomas Murante, Brooke N Horton, Jacinto De La Cruz Diaz, Louis DiDone

Genetics· July 2016

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Structure-activity relationships for the antifungal activity of selective estrogen receptor antagonists related to tamoxifen.
Arielle Butts, Jennifer A Martin, Louis DiDone, Erin K Bradley, Mitchell Mutz

PLoS One· April 2016

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Antitumor/Antifungal Celecoxib Derivative AR-12 is a Non-Nucleoside Inhibitor of the ANL-Family Adenylating Enzyme Acetyl CoA Synthetase.
Kristy Koselny, Julianne Green, Lacey Favazzo, Virginia E Glazier, Louis DiDone

ACS Infect Dis· April 2016

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A High Throughput Screening Assay for Anti-Mycobacterial Small Molecules Based on Adenylate Kinase Release as a Reporter of Cell Lysis.
Lauren Forbes, Katherine Ebsworth-Mojica, Louis DiDone, Shao-Gang Li, Joel S Freundlich

PLoS One· March 2016

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High-Throughput Screen in Identifies a Novel Molecular Scaffold That Inhibits Cell Wall Integrity Pathway Signaling.
Kate Hartland, Jun Pu, Michelle Palmer, Sivaraman Dandapani, Philip N Moquist, Louis DiDone

ACS Infect Dis· January 2016

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Estrogen receptor antagonists are anti-cryptococcal agents that directly bind EF hand proteins and synergize with fluconazole in vivo.
Arielle Butts, Kristy Koselny, Yeissa Chabrier-Roselló, Camile P Semighini, Jessica C S Brown, Louis DiDone

mBio· February 2014

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A repurposing approach identifies off-patent drugs with fungicidal cryptococcal activity, a common structural chemotype, and pharmacological properties relevant to the treatment of cryptococcosis.
Arielle Butts, Louis DiDone, Kristy Koselny, Bonnie K Baxter, Yeissa Chabrier-Rosello

Eukaryot Cell· February 2013

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Adenylate kinase release as a high-throughput-screening-compatible reporter of bacterial lysis for identification of antibacterial agents.
Anna C Jacobs, Louis Didone, Jennielle Jobson, Madeline K Sofia, Damian Krysan

Antimicrob Agents Chemother· January 2013

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Cryptococcus neoformans phosphoinositide-dependent kinase 1 (PDK1) ortholog is required for stress tolerance and survival in murine phagocytes.
Yeissa Chabrier-Roselló, Kimberly J Gerik, Kristy Koselny, Louis DiDone, Jennifer K Lodge

Eukaryot Cell· January 2013

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A novel assay of biofilm antifungal activity reveals that amphotericin B and caspofungin lyse Candida albicans cells in biofilms.
Louis DiDone, Duana Oga, Damian J Krysan

Yeast· August 2011

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Identification, in vitro activity and mode of action of phosphoinositide-dependent-1 kinase inhibitors as antifungal molecules.
Bonnie K Baxter, Louis DiDone, Duana Ogu, Stanford Schor, Damian J Krysan

ACS Chem Biol· May 2011

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Extracellular secretion of overexpressed glycosylphosphatidylinositol-linked cell wall protein Utr2/Crh2p as a novel protein quality control mechanism in Saccharomyces cerevisiae.
Kelly A Miller, Louis DiDone, Damian J Krysan

Eukaryot Cell· November 2010

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A high-throughput assay of yeast cell lysis for drug discovery and genetic analysis.
Louis DiDone, Thomas Scrimale, Bonnie K Baxter, Damian J Krysan

Nat Protoc· June 2010

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Antifungal activity of tamoxifen: in vitro and in vivo activities and mechanistic characterization.
Kristy Dolan, Sara Montgomery, Bradley Buchheit, Louis Didone, Melanie Wellington

Antimicrob Agents Chemother· August 2009

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The unfolded protein response is induced by the cell wall integrity mitogen-activated protein kinase signaling cascade and is required for cell wall integrity in Saccharomyces cerevisiae.
Thomas Scrimale, Louis Didone, Karen L de Mesy Bentley, Damian J Krysan

Mol Biol Cell· January 2009

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A high-throughput screening assay for small molecules that disrupt yeast cell integrity.
Damian J Krysan, Louis Didone

J Biomol Screen· August 2008

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