Publications by authors named "Louis Grenier"

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Discovery of a Selective Phosphoinositide-3-Kinase (PI3K)-γ Inhibitor (IPI-549) as an Immuno-Oncology Clinical Candidate.
Catherine A Evans, Tao Liu, André Lescarbeau, Somarajan J Nair, Louis Grenier

ACS Med Chem Lett· September 2016

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Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.
Martin R Tremblay, Marta Nevalainen, Somarajan J Nair, James R Porter, Alfredo C Castro, Louis Grenier

J Med Chem· November 2008

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Development of 17-allylamino-17-demethoxygeldanamycin hydroquinone hydrochloride (IPI-504), an anti-cancer agent directed against Hsp90.
Jens R Sydor, Emmanuel Normant, Christine S Pien, James R Porter, Jie Ge, Louis Grenier

Proc Natl Acad Sci U S A· November 2006

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Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.
Jie Ge, Emmanuel Normant, James R Porter, Janid A Ali, Marlene S Dembski, Louis Grenier

J Med Chem· July 2006

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Novel IKK inhibitors: beta-carbolines.
Alfredo C Castro, Luan C Dang, François Soucy, Louis Grenier, Hormoz Mazdiyasni

Bioorg Med Chem Lett· July 2003

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Protein-rich diet attenuates cyclosporin A-induced renal tubular damage in rats.
Marianne Pons, Isabelle Plante, Michel LeBrun, Pierrette Gourde, Marie Simard, Louis Grenier

J Ren Nutr· April 2003

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A Practical and Diastereoselective Synthesis of Ketomethylene Dipeptide Isosteres of the Type AAPsi[COCH(2)]Asp.
Robert Déziel, Raymond Plante, Valérie Caron, Louis Grenier, Montse Llinas-Brunet

J Org Chem· April 1996

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