Publications by authors named "Louis Lello"

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Efficient blockLASSO for polygenic scores with applications to all of us and UK Biobank.
Timothy G Raben, Louis Lello, Erik Widen, Stephen D H Hsu

BMC Genomics· March 2025

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Correspondence on "Clinical utility of polygenic risk scores for embryo selection: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG)" by Grebe et al.
Erik Widen, Louis Lello, Jennifer Eccles, Diego Marin, Nathan R Treff

Genet Med· August 2024

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Biobank-scale methods and projections for sparse polygenic prediction from machine learning.
Timothy G Raben, Louis Lello, Erik Widen, Stephen D H Hsu

Sci Rep· July 2023

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Scientific refutation of ESHG statement on embryo selection.
Laurent Christian Asker Melchior Tellier, Nathan Robert Treff, Stephen Dao Hui Hsu, Louis Lello, Erik Widen

Eur J Hum Genet· March 2023

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Sibling variation in polygenic traits and DNA recombination mapping with UK Biobank and IVF family data.
Louis Lello, Maximus Hsu, Erik Widen, Timothy G Raben

Sci Rep· January 2023

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Polygenic Health Index, General Health, and Pleiotropy: Sibling Analysis and Disease Risk Reduction.
Erik Widen, Louis Lello, Timothy G Raben, Laurent C A M Tellier, Stephen D H Hsu

Sci Rep· October 2022

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From Genotype to Phenotype: Polygenic Prediction of Complex Human Traits.
Timothy G Raben, Louis Lello, Erik Widen, Stephen D H Hsu

Methods Mol Biol· April 2022

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Embryo Screening for Polygenic Disease Risk: Recent Advances and Ethical Considerations.
Laurent C A M Tellier, Jennifer Eccles, Nathan R Treff, Louis Lello, Simon Fishel

Genes (Basel)· July 2021

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Machine Learning Prediction of Biomarkers from SNPs and of Disease Risk from Biomarkers in the UK Biobank.
Erik Widen, Timothy G Raben, Louis Lello, Stephen D H Hsu

Genes (Basel)· June 2021

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PREIMPLANTATION GENETIC TESTING: Preimplantation genetic testing for polygenic disease risk.
Nathan R Treff, Diego Marin, Louis Lello, Stephen Hsu, Laurent C A M Tellier

Reproduction· November 2020

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Sibling validation of polygenic risk scores and complex trait prediction.
Louis Lello, Timothy G Raben, Stephen D H Hsu

Sci Rep· August 2020

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Genetic architecture of complex traits and disease risk predictors.
Soke Yuen Yong, Timothy G Raben, Louis Lello, Stephen D H Hsu

Sci Rep· July 2020

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Preimplantation Genetic Testing for Polygenic Disease Relative Risk Reduction: Evaluation of Genomic Index Performance in 11,883 Adult Sibling Pairs.
Nathan R Treff, Jennifer Eccles, Diego Marin, Edward Messick, Louis Lello

Genes (Basel)· June 2020

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Author Correction: Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer.
Louis Lello, Timothy G Raben, Soke Yuen Yong, Laurent C A M Tellier, Stephen D H Hsu

Sci Rep· November 2019

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Genomic Prediction of 16 Complex Disease Risks Including Heart Attack, Diabetes, Breast and Prostate Cancer.
Louis Lello, Timothy G Raben, Soke Yuen Yong, Laurent C A M Tellier, Stephen D H Hsu

Sci Rep· October 2019

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Validation of concurrent preimplantation genetic testing for polygenic and monogenic disorders, structural rearrangements, and whole and segmental chromosome aneuploidy with a single universal platform.
Nathan R Treff, Raymond Zimmerman, Elan Bechor, Jeff Hsu, Bhavini Rana, Louis Lello

Eur J Med Genet· August 2019

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Complex-Trait Prediction in the Era of Big Data.
Gustavo de Los Campos, Ana Ines Vazquez, Stephen Hsu, Louis Lello

Trends Genet· October 2018

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Accurate Genomic Prediction of Human Height.
Louis Lello, Steven G Avery, Laurent Tellier, Ana I Vazquez, Gustavo de Los Campos

Genetics· October 2018

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